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Bloody Minded

Bloody Minded

Bloody Minded Crew

Baffled by blood? Confused by coags? Traumatised by TTP? Planning on quitting medical school because you've just finished haem block? Join the registrars of the Bloody Minded Crew as they tour the world of haematology one topic at at a time while procrastinating from their day jobs.
Your time is precious, so to maximise your return we look at each topic at a variety of levels so you can tailor your learning. Check out more at www.bloodyminded.com.au

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Top 10 Bloody Minded Episodes

Goodpods has curated a list of the 10 best Bloody Minded episodes, ranked by the number of listens and likes each episode have garnered from our listeners. If you are listening to Bloody Minded for the first time, there's no better place to start than with one of these standout episodes. If you are a fan of the show, vote for your favorite Bloody Minded episode by adding your comments to the episode page.

Help! After a disastrous 3 way ward swap you now have to cover the haem ward as an intern in... 45 minutes time. If only there were some way you could get a crash course on everything you might need to know. Well are you in luck today! Join our new guest host Dr Alison Chandler for a whole new subtype of episodes, our new "On the Wards" series.These are for those new interns and residents who have been drafted to cover the dreaded haem wards and need to prepare all the practical day to day things.
On this inaugural On The Wards episode we'll cover the haematology ward round, how to read a haematology note and plan for some planned admissions. Keep an eye out for these every so often in between our conventional topics.
Timestamps
1:09 - Who is Dr Alison Chandler?
3:43 - What makes haem scary?
8:20 - Three top tips for haem JMOs
14:34 - The haem ward round - letters and numbers!
27:50 - Always look at the blood count
34:08 - Planned admissions
38:02 - Extra things to do on haem

Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

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MAHA TMA Gandhi once said a cell for a cell makes the whole body anaemic, or something along those lines. There’s so much more to DAT negative haemolysis than just DIC. Get out those buckets and put your sorting hats on - it’s time to go where detective Coombs never dared to and look over the DAT negative haemolytic processes.
Timestamps
2:42 - Approach to DAT negatives - main categories
4:53 - Intrinsic Bucket 1: Membrane disorders
16:16 - Intrinsic Bucket 2: Enzyme disorders
18:51 - Intrinsic Bucket 3: Haemoglobin disorders
24:05 - Extrinsic Bucket 1: Microangiopathies
26:54 - Extrinsic Bucket 2: Infections
28:07 - Extrinsic Bucket 3: "Macroangiopathies"
30:58 - Extrinsic Bucket 4: Liver stuff
34:07 - Take home messages

Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

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Do you have a FLAER for the exotic? All at sea without your GPI-anchor? Come on a deep dive into the world of paroxysmal nocturnal haemoglobinuria - which isn’t really a disease of haemolysis at all but hey we're putting it here anyway and you can't stop us
Timestamps
1:46 - What is PNH? Baby don't hurt me...
4:48 - Signs and Symptoms
7:27 - Pathophysiology
11:27 - Diagnosis
17:04 - Managing Pretty Not Happy Blood

Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

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Bloody Minded - Episode 0 - Introductions
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05/14/24 • 4 min

Optional Introductions - Skip to Episode 1 if you're after content
We're excited to launch Bloody Minded - a haematology podcast for those who want an extra little drop of knowledge no matter where you are in your medical journey. Learn a little bit about your hosts and how we'll be formatting this show

Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

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Is there a glow surrounding your red cells? Things feeling heated in your reticuloendothelial system? An antibody to keep your bed warm at night? We don’t know where this is going either but grab a coconut and hop in the pool because we are excited to welcome you back with a chat about warm autoimmune haemolysis!
Timestamps
00:57 - Introduction & Case
05:08 - wAIHA - What is it?
07:04 - Reminder about the RES
08:35 - Surface Targets & Drugs
11:45 - Brief Mid-Ep Summary
13:05 - Causes
22:30 - Treatment
26:20 - Misc Points & Episode Summary

Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

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Have you been spending too much time outside of the lab lately? So have we! Come with us on a whirlwind tour through the high altitudes of thermal amplitudes, the chilly depths of cold agg titres, the bright lights of EMA testing, the flocculated wetlands of unstable haemoglobins (don’t ask) and more! All from the safety of the lab, of course. We don’t go outside.
Timestamps
2:14 - Cold agglutinin testing
8:05 - PCH (Pretty Cool Haem)/Donath-Landsteiner testing
14:52 - G6PD testing
23:25 - Unstable Haemoglobin testing
28:55 - Take homes

Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

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It’s Test. Coombs Test. And I like my erythrocytes shaken, not stirred.” Return the lab (where some of the Bloody Minded Crew truly belong) and uncover the secrets of the most important test in haemolysis - the Direct Antiglobulin Test. Learn to whisper its secrets and it can guide you to identifying the true culprit behind these broken red cells.
Timestamps:
0:57 - Coombs Noir
2:05 - Naming History
4:32 - DAT in the Lab
11:52 - Doing a DAT - Exam Version
14:35 - Eluates (Briefly)
15:45 - False Positives & Negatives
18:24 - When to DAT?
21:55 - Distilling the DAT - Interpretation
25:38 - DAT-Vanced Topics
29:24 - Takehome Points

Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

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Bloody Minded - Episode 22 - B is for B-Cell | Immunology 101
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11/05/24 • 35 min

A is for Antibody. B is for B-cell. C is for Cryoglobul... wait no we’ve covered that already. If you struggle to tell your thymus from an isthmus, can’t see the humour in humoural immunity and think a bursa is just some fancy elbow cushion then THIS is the episode for you. Join the Bloody Minded Crew as they dust off their undergraduate immunology degrees, get back to the classroom and cover the foundations of the immune system in preparation for tackling our upcoming malignant diseases.
Timestamps
3:43 - The Immune System
4:50 - The Spleen
5:36 - The Thymus
6:19 - The Lymph Nodes
8:19 - The Innate Immune System
13:16 - The Adaptive Immune System
16:56 - VDJ recombination
21:21 - MHC/HLA
24:54 - Antibodies!
27:42 - Class switching
28:58 - The purpose of Plasma Cells
30:33 - An immune response - start to finish

Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

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Haemolysis? Do I really hapto send off more tests? This is reticulous! Now you know what a red cell is - lets learn about how they can break down. Join us as we explore what your boss actually wanted you to do when they asked for a haemolysis screen, and about Cale's deep seated distrust of hepatologists.
Timestamps
2:30 - Haemolysis - what is it (good for?)
7:58 - Reticulocytes? What a reticulous name for a cell
9:36 - LDH - Nick will talk about biochemistry here, I'm SORRY okay?
11:36 - Bilirubin feat. Gilbert - winner of the 2015 Triple J's Hottest 100
16:10 - Haptoglobin (with apologies to my anaesthetist friends)
20:32 - Who is DAT?
23:49 - Haemolysis screen recap - click here when med reg is impatient
27:35 - Take home messages!

Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

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Ordered something you shouldn’t have and accidentally found a paraprotein again? Shame on you, but now you have to do something with it. Maybe you were genuinely suspicious for myeloma. If incidentally discovered lab findings are leaving you smouldering, this is the episode for you!
Join Nick, Cale and Bashar as they chat about the spectrum of plasma cell dyscrasias, and cover the precursor conditions MGUS and Smouldering Myeloma.
Timestamps
2:53 - What is a paraprotein?
5:56 - The heavy chain component
9:40 - The spectrum of plasma cell disorders
10:12 - MGUS
11:33 - How common is MGUS?
15:24 - You've found a paraprotein - what next?
17:38 - IMWG MGUS Criteria
19:47 - Mayo Score for Risk Stratification
22:25 - Serum free light chain ratio
24:25 - Bence Jones proteins
26:21 - Smouldering myeloma
27:30 - IMWG Smouldering myeloma criteria
29:16 - Risk of progression to MM

Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

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FAQ

How many episodes does Bloody Minded have?

Bloody Minded currently has 24 episodes available.

What topics does Bloody Minded cover?

The podcast is about Life Sciences, Med School, Medicine, Podcasts, Education, Science and Foam.

What is the most popular episode on Bloody Minded?

The episode title 'Episode 11 - What is Blood ft. Erythrocytes | Haematopoiesis & Haematinics Overview' is the most popular.

What is the average episode length on Bloody Minded?

The average episode length on Bloody Minded is 32 minutes.

How often are episodes of Bloody Minded released?

Episodes of Bloody Minded are typically released every 7 days.

When was the first episode of Bloody Minded?

The first episode of Bloody Minded was released on May 14, 2024.

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