Bloody Minded
Bloody Minded Crew
Baffled by blood? Confused by coags? Traumatised by TTP? Planning on quitting medical school because you've just finished haem block? Join the registrars of the Bloody Minded Crew as they tour the world of haematology one topic at at a time while procrastinating from their day jobs.
Your time is precious, so to maximise your return we look at each topic at a variety of levels so you can tailor your learning. Check out more at www.bloodyminded.com.au
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Top 10 Bloody Minded Episodes
Goodpods has curated a list of the 10 best Bloody Minded episodes, ranked by the number of listens and likes each episode have garnered from our listeners. If you are listening to Bloody Minded for the first time, there's no better place to start than with one of these standout episodes. If you are a fan of the show, vote for your favorite Bloody Minded episode by adding your comments to the episode page.
07/16/24 • 35 min
Echis carinatus, Daboia russelii, Uxyuranus scullatellas. Never has so much been owed by so many humans to so few... snakes. In this split episode, For the first time the Bloody Minded Crew is delighted to welcome guests! Join our coagulation experts Dr Maeve Crowley and Kent Chapman for a tour of the wonderful world of exotic clotting times.
This episode was so big we split it in half! In Part 2 of this episode we step out of the lab and chat with consultant haematologist Dr Maeve Crowley about the clinical uses of snake based testing and the subtleties of lupus anticoagulant testing.
Timestamps
1:43 - Introductions
05:07 - The DRVVT
06:57 - LA Testing in Practice
09:00 - Mixing Studies
13:33 - Testing and Anticoagulation
19:27 - Significant LAs
21:20 - RAPS, TRAPS and Decision Making in LA
27:20 - Taipan and Echis Times
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
03/18/25 • 37 min
Perfectly balanced, as all things should be. All that blood doesn’t just arrive when you snap your fingers together. The REALITY is you need the TIME and SPACE to thaw that frozen plasma and the strength of MIND to keep all the components in the right ratios. Only the chosen few with the POWER of transfusion medicine and the SOUL of the laboratory can direct the most immense of transfusions - the massive transfusion. Listen to this episode and maybe you can run the GAUNTLET of the MTP.
Timestamps:
0:53 - Get ready for MASSIVE. TRANSFUSION. PROTOCOL.
1:45 - What is an MTP?
4:10 - A bleedy example
7:11 - Activating the MTP
8:52 - Consent in MTPs
11:16 - MTP packs
12:27 - Crossing plasma groups
15:30 - 1:1:1 Transfusion
17:29 - Whole Blood Transfusion
19:49 - Acidosis
22:21 - Hypothermia
23:14 - Hypocalcaemia
25:12 - Resus Associated Coagulopathy
25:49 - DIC
26:58 - Trauma Induced Coagulopathy
29:19 - Summary of Resuscitative Endpoints
31:05 - Viscoelastic testing
33:12 - Factor Concentrates
34:55 - Take home messages
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
Episode 0 - Introductions
Bloody Minded
05/14/24 • 4 min
Optional Introductions - Skip to Episode 1 if you're after content
We're excited to launch Bloody Minded - a haematology podcast for those who want an extra little drop of knowledge no matter where you are in your medical journey. Learn a little bit about your hosts and how we'll be formatting this show
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
04/01/25 • 54 min
IVIG & Rituximab – both involve Antibodies – and both can lead to infusion reactions that you may be called to as a junior doctor. But where do these antibodies even come from? Why are we even giving these treatments? What are you meant to do when called to review the patient? Head back to the wards, get your cheese ready and welcome back consultant haematologist Dr Alison Chandler to the pod to teach us about infusion reactions
Timestamps:
0:53 - Yes, Nick is having a stroke
3:58 - Intro to IVIg and Rituximab
5:22 - What is IVIg?
6:46 - Where does IVIg come from
9:54 - Types of IVIg
13:58 - Indications for IVIg
19:17 - Administering IVIg
21:28 - Acute IVIg reactions
29:47 - Delayed IVIg reactions
32:31 - IVIg summary
33:36 - Intro to Rituximab
35:39 - Indications for Rituximab
40:45 - Rituximab Reactions
50:29 - Rituximab Summary
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
03/25/25 • 35 min
Keen to augment your blood transfusion game but confused as to when, where and why? Join the Bloody Minded boffins as we cover all the major modifications to blood products you can order. More importantly, why you should and sometimes shouldn't bother ordering them. Have a sensible conversation with your blood bank after you listen to this episode.
Timestamps:
00:58 - How the blood bank actually works
04:03 - Aged Products
07:30 - Frozen Cells
10:32 - Transfusing the Bombay phenotype
12:10 - Leukodepletion
13:57 - CMV negative
19:17 - Irradiated units
19:52 - TA-GVHD
27:58 - HLA Matching
32:46 - Take home messages
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
08/13/24 • 28 min
Haemolysis? Do I really hapto send off more tests? This is reticulous! Now you know what a red cell is - lets learn about how they can break down. Join us as we explore what your boss actually wanted you to do when they asked for a haemolysis screen, and about Cale's deep seated distrust of hepatologists.
Timestamps
2:30 - Haemolysis - what is it (good for?)
7:58 - Reticulocytes? What a reticulous name for a cell
9:36 - LDH - Nick will talk about biochemistry here, I'm SORRY okay?
11:36 - Bilirubin feat. Gilbert - winner of the 2015 Triple J's Hottest 100
16:10 - Haptoglobin (with apologies to my anaesthetist friends)
20:32 - Who is DAT?
23:49 - Haemolysis screen recap - click here when med reg is impatient
27:35 - Take home messages!
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
Episode 7 - In the Lab: Factor Assays
Bloody Minded
06/25/24 • 34 min
One step, two step, red step, blue step! Get stuck in to assessing factor levels in this episode looking at the differences between one and two step factor assays, the basis of chromogenic testing and how to resolve discrepancies between different methods.
Timestamps:
01:33 Intro to Factor Assays
04:33 One-Stage Assays
09:33 Historical Diversion - What's an IU?
15:28 Factor VIII levels
17:15 Two-Stage Assays
21:31 Resolving Discrepancies
25:24 FXIII Assays
32:32 Summary
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
08/20/24 • 30 min
“It’s Test. Coombs Test. And I like my erythrocytes shaken, not stirred.” Return the lab (where some of the Bloody Minded Crew truly belong) and uncover the secrets of the most important test in haemolysis - the Direct Antiglobulin Test. Learn to whisper its secrets and it can guide you to identifying the true culprit behind these broken red cells.
Timestamps:
0:57 - Coombs Noir
2:05 - Naming History
4:32 - DAT in the Lab
11:52 - Doing a DAT - Exam Version
14:35 - Eluates (Briefly)
15:45 - False Positives & Negatives
18:24 - When to DAT?
21:55 - Distilling the DAT - Interpretation
25:38 - DAT-Vanced Topics
29:24 - Takehome Points
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
09/17/24 • 36 min
MAHA TMA Gandhi once said a cell for a cell makes the whole body anaemic, or something along those lines. There’s so much more to DAT negative haemolysis than just DIC. Get out those buckets and put your sorting hats on - it’s time to go where detective Coombs never dared to and look over the DAT negative haemolytic processes.
Timestamps
2:42 - Approach to DAT negatives - main categories
4:53 - Intrinsic Bucket 1: Membrane disorders
16:16 - Intrinsic Bucket 2: Enzyme disorders
18:51 - Intrinsic Bucket 3: Haemoglobin disorders
24:05 - Extrinsic Bucket 1: Microangiopathies
26:54 - Extrinsic Bucket 2: Infections
28:07 - Extrinsic Bucket 3: "Macroangiopathies"
30:58 - Extrinsic Bucket 4: Liver stuff
34:07 - Take home messages
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
01/07/25 • 54 min
Thankfully, it's time for an actual expert to join us again on Bloody Minded! We are thrilled to be sitting down and chatting with A/Prof. Tracy King, Myeloma CNC from RPA Hospital in Sydney, Co-Founder and past president of the HSANZ Nursing Group. From convenient treatment schedulers to the side effects we should be thinking more about to many ideas to improve clinical practice, this is a veritable hour of power worth diving into.
TIMESTAMPS
2:23 - Intro to Tracy King
3:30 - A Nightingale Sang in Hammersmith Square
5:22 - How did you get into myeloma nursing?
9:35 - If not nursing, what?
10:50 - What is a CNC?
14:12 - Nursing expertise in myeloma - best supportive care
16:57 - The most asked questions
19:54 - Strategies to manage complex regimens
23:13 - MyeTxScheduler - A Godsend
26:37 - What do we miss, what should we be asking more?
28:21 - The crux of communication issues
29:33 - "What matters to you today"
29:49 - Patient advocacy groups
32:04 - Steroid side effects - there's just so much dex...
35:37 - M protein variations - how to see the forest for the trees
38:22 - Time toxicity
45:44 - Quality of life assessment tools
49:35 - How to get started in advocacy/education/further work?
51:57 - Organisations - find your tribe
Also we promised to link MyeTx here so have at it
https://rego.interact.technology/myetx/#/main
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
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FAQ
How many episodes does Bloody Minded have?
Bloody Minded currently has 42 episodes available.
What topics does Bloody Minded cover?
The podcast is about Life Sciences, Med School, Medicine, Podcasts, Education, Science and Foam.
What is the most popular episode on Bloody Minded?
The episode title 'Episode 11 - What is Blood ft. Erythrocytes | Haematopoiesis & Haematinics Overview' is the most popular.
What is the average episode length on Bloody Minded?
The average episode length on Bloody Minded is 37 minutes.
How often are episodes of Bloody Minded released?
Episodes of Bloody Minded are typically released every 7 days.
When was the first episode of Bloody Minded?
The first episode of Bloody Minded was released on May 14, 2024.
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