Bloody Minded
Bloody Minded Crew
Baffled by blood? Confused by coags? Traumatised by TTP? Planning on quitting medical school because you've just finished haem block? Join the registrars of the Bloody Minded Crew as they tour the world of haematology one topic at at a time while procrastinating from their day jobs.
Your time is precious, so to maximise your return we look at each topic at a variety of levels so you can tailor your learning. Check out more at www.bloodyminded.com.au
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Top 10 Bloody Minded Episodes
Goodpods has curated a list of the 10 best Bloody Minded episodes, ranked by the number of listens and likes each episode have garnered from our listeners. If you are listening to Bloody Minded for the first time, there's no better place to start than with one of these standout episodes. If you are a fan of the show, vote for your favorite Bloody Minded episode by adding your comments to the episode page.
07/16/24 • 35 min
Echis carinatus, Daboia russelii, Uxyuranus scullatellas. Never has so much been owed by so many humans to so few... snakes. In this split episode, For the first time the Bloody Minded Crew is delighted to welcome guests! Join our coagulation experts Dr Maeve Crowley and Kent Chapman for a tour of the wonderful world of exotic clotting times.
This episode was so big we split it in half! In Part 2 of this episode we step out of the lab and chat with consultant haematologist Dr Maeve Crowley about the clinical uses of snake based testing and the subtleties of lupus anticoagulant testing.
Timestamps
1:43 - Introductions
05:07 - The DRVVT
06:57 - LA Testing in Practice
09:00 - Mixing Studies
13:33 - Testing and Anticoagulation
19:27 - Significant LAs
21:20 - RAPS, TRAPS and Decision Making in LA
27:20 - Taipan and Echis Times
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
Episode 0 - Introductions
Bloody Minded
05/14/24 • 4 min
Optional Introductions - Skip to Episode 1 if you're after content
We're excited to launch Bloody Minded - a haematology podcast for those who want an extra little drop of knowledge no matter where you are in your medical journey. Learn a little bit about your hosts and how we'll be formatting this show
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
08/13/24 • 28 min
Haemolysis? Do I really hapto send off more tests? This is reticulous! Now you know what a red cell is - lets learn about how they can break down. Join us as we explore what your boss actually wanted you to do when they asked for a haemolysis screen, and about Cale's deep seated distrust of hepatologists.
Timestamps
2:30 - Haemolysis - what is it (good for?)
7:58 - Reticulocytes? What a reticulous name for a cell
9:36 - LDH - Nick will talk about biochemistry here, I'm SORRY okay?
11:36 - Bilirubin feat. Gilbert - winner of the 2015 Triple J's Hottest 100
16:10 - Haptoglobin (with apologies to my anaesthetist friends)
20:32 - Who is DAT?
23:49 - Haemolysis screen recap - click here when med reg is impatient
27:35 - Take home messages!
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
Episode 7 - In the Lab: Factor Assays
Bloody Minded
06/25/24 • 34 min
One step, two step, red step, blue step! Get stuck in to assessing factor levels in this episode looking at the differences between one and two step factor assays, the basis of chromogenic testing and how to resolve discrepancies between different methods.
Timestamps:
01:33 Intro to Factor Assays
04:33 One-Stage Assays
09:33 Historical Diversion - What's an IU?
15:28 Factor VIII levels
17:15 Two-Stage Assays
21:31 Resolving Discrepancies
25:24 FXIII Assays
32:32 Summary
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
08/20/24 • 30 min
“It’s Test. Coombs Test. And I like my erythrocytes shaken, not stirred.” Return the lab (where some of the Bloody Minded Crew truly belong) and uncover the secrets of the most important test in haemolysis - the Direct Antiglobulin Test. Learn to whisper its secrets and it can guide you to identifying the true culprit behind these broken red cells.
Timestamps:
0:57 - Coombs Noir
2:05 - Naming History
4:32 - DAT in the Lab
11:52 - Doing a DAT - Exam Version
14:35 - Eluates (Briefly)
15:45 - False Positives & Negatives
18:24 - When to DAT?
21:55 - Distilling the DAT - Interpretation
25:38 - DAT-Vanced Topics
29:24 - Takehome Points
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
09/17/24 • 36 min
MAHA TMA Gandhi once said a cell for a cell makes the whole body anaemic, or something along those lines. There’s so much more to DAT negative haemolysis than just DIC. Get out those buckets and put your sorting hats on - it’s time to go where detective Coombs never dared to and look over the DAT negative haemolytic processes.
Timestamps
2:42 - Approach to DAT negatives - main categories
4:53 - Intrinsic Bucket 1: Membrane disorders
16:16 - Intrinsic Bucket 2: Enzyme disorders
18:51 - Intrinsic Bucket 3: Haemoglobin disorders
24:05 - Extrinsic Bucket 1: Microangiopathies
26:54 - Extrinsic Bucket 2: Infections
28:07 - Extrinsic Bucket 3: "Macroangiopathies"
30:58 - Extrinsic Bucket 4: Liver stuff
34:07 - Take home messages
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
Episode 22 - B is for B-Cell | Immunology 101
Bloody Minded
11/05/24 • 35 min
A is for Antibody. B is for B-cell. C is for Cryoglobul... wait no we’ve covered that already. If you struggle to tell your thymus from an isthmus, can’t see the humour in humoural immunity and think a bursa is just some fancy elbow cushion then THIS is the episode for you. Join the Bloody Minded Crew as they dust off their undergraduate immunology degrees, get back to the classroom and cover the foundations of the immune system in preparation for tackling our upcoming malignant diseases.
Timestamps
3:43 - The Immune System
4:50 - The Spleen
5:36 - The Thymus
6:19 - The Lymph Nodes
8:19 - The Innate Immune System
13:16 - The Adaptive Immune System
16:56 - VDJ recombination
21:21 - MHC/HLA
24:54 - Antibodies!
27:42 - Class switching
28:58 - The purpose of Plasma Cells
30:33 - An immune response - start to finish
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
Episode 34 - On the Wards: I would do anything for blood – but I won’t do that | Transfusion Reactions
Bloody Minded
02/04/25 • 62 min
Do you fear – The Power of Blood? Have you been warned – You can’t Hurry Blood? Today we tackle all the ways Blood (and love) can go wrong. . . and how to manage it on the wards.
Too cryptic? Join Bloody Minded's own consultant haematologist Dr Alison Chandler and the rest of the Bloody Minded Crew as we cover the many and varied reactions patients can have when you try and fix that haemoglobin level on the ward.
Timestamps
00:53 - 3-4 nerds chatting about nonsense
03:37 - Your first transfusion reaction
05:08 - What is a transfusion reaction?
5:52 - Categorising transfusion reactions
7:26 - Acute febrile reactions
17:20 - Summary of acute febrile reactions
17:45 - Acute non-febrile transfusion reactions
22:11 - Workup and management of an acute reaction
37:44 - Delayed febrile reactions
50:08 - Delayed non-febrile reactions
53:46 - Summaries
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
Episode 20 - TMI about TLAs | TTP & PNH with Dr Hsu
Bloody Minded
10/08/24 • 43 min
Tired of listening to the three of us? Why not listen to an actual expert!? Today we're joined by Dr Danny Hsu, consultant haematologist, clinical lead of Immune Haematology & Therapeutic Apheresis at Liverpool Hospital, THANZ council member and all around top bloke to dig down into the nitty gritty of TTP and PNH.
Any question you might have about these conditions Dr Hsu is your go to. Sadly we didn't ask him every question you might have, but he certainly came up with incredible answers to the ones we asked of him.
Timestamps
1:15 - Intro to Dr Danny Hsu!
7:19 - Getting into nonmalignant haem
9:55 - TTP in practice
14:03 - Intricacies of TTP diagnosis
25:15 - Managing TTP in the the longer term
28:55 - PNH chat!
38:57 - Final words and outro
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
01/07/25 • 54 min
Thankfully, it's time for an actual expert to join us again on Bloody Minded! We are thrilled to be sitting down and chatting with A/Prof. Tracy King, Myeloma CNC from RPA Hospital in Sydney, Co-Founder and past president of the HSANZ Nursing Group. From convenient treatment schedulers to the side effects we should be thinking more about to many ideas to improve clinical practice, this is a veritable hour of power worth diving into.
TIMESTAMPS
2:23 - Intro to Tracy King
3:30 - A Nightingale Sang in Hammersmith Square
5:22 - How did you get into myeloma nursing?
9:35 - If not nursing, what?
10:50 - What is a CNC?
14:12 - Nursing expertise in myeloma - best supportive care
16:57 - The most asked questions
19:54 - Strategies to manage complex regimens
23:13 - MyeTxScheduler - A Godsend
26:37 - What do we miss, what should we be asking more?
28:21 - The crux of communication issues
29:33 - "What matters to you today"
29:49 - Patient advocacy groups
32:04 - Steroid side effects - there's just so much dex...
35:37 - M protein variations - how to see the forest for the trees
38:22 - Time toxicity
45:44 - Quality of life assessment tools
49:35 - How to get started in advocacy/education/further work?
51:57 - Organisations - find your tribe
Also we promised to link MyeTx here so have at it
https://rego.interact.technology/myetx/#/main
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
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FAQ
How many episodes does Bloody Minded have?
Bloody Minded currently has 37 episodes available.
What topics does Bloody Minded cover?
The podcast is about Life Sciences, Med School, Medicine, Podcasts, Education, Science and Foam.
What is the most popular episode on Bloody Minded?
The episode title 'Episode 11 - What is Blood ft. Erythrocytes | Haematopoiesis & Haematinics Overview' is the most popular.
What is the average episode length on Bloody Minded?
The average episode length on Bloody Minded is 37 minutes.
How often are episodes of Bloody Minded released?
Episodes of Bloody Minded are typically released every 7 days.
When was the first episode of Bloody Minded?
The first episode of Bloody Minded was released on May 14, 2024.
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