Episode 5 - In the Lab: Thrombin Time, Fibrinogen and Anti-Xa assays
06/11/24 • 36 min
To infinXa and beyond! Let go of your veXation and eXalt our eXacting approach to coagulation testing. You'll know eXactly what you need for your eXams as long as they ask you about anti-Xa testing, thrombin times, fibrinogen and absolutely nothing else.
Timestamps
0:00 - Introductions
2:40 - Thombin Time - Lab
5:45 - Thrombin Time - Clinical
9:24 - Thrombin Time - Variants
11:06 - Anti-Xa Intro
14:53 - Anti-Xa - Lab
19:04 - Anti-Xa - Clinical
25:21 - Santa-Clauss (Fibrinogen)
30:20 - Cases
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
To infinXa and beyond! Let go of your veXation and eXalt our eXacting approach to coagulation testing. You'll know eXactly what you need for your eXams as long as they ask you about anti-Xa testing, thrombin times, fibrinogen and absolutely nothing else.
Timestamps
0:00 - Introductions
2:40 - Thombin Time - Lab
5:45 - Thrombin Time - Clinical
9:24 - Thrombin Time - Variants
11:06 - Anti-Xa Intro
14:53 - Anti-Xa - Lab
19:04 - Anti-Xa - Clinical
25:21 - Santa-Clauss (Fibrinogen)
30:20 - Cases
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
Previous Episode
Episode 4 - Forever Alone: The Isolated Prolonged aPTT
Being alone can be difficult - and we would know! How should we think about a long aPTT when the rest of the coag screen looks normal? Join Bloody Minded crew as we learn how to tackle this surprisingly common (and surprisingly tricky) problem.
Timestamps
00:00 - Introductions
02:21 - aPTT Revision
03:59 - A case
08:04 - Testing for heparins
10:10 - Back to the case
11:10 - DOACs and the aPTT
12:34 - Mid Episode Recap
13:32 - What if not heparin?
16:56 - Mixing studies
21:11 - PT Mixing
23:01 - Case returns
24:17 - Summary
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
Next Episode
Episode 6 - In the Lab: Lupus Anticoagulants
Finding your coagulation knowledge "LAC-ing"? Do you also hate things that were named terribly and thrive on pedantry? This week we pop the hood on that most mysterious of lab tests - the lupus anticoagulant. Listen to this episode again in 12 weeks time for an authentic lupus anticoagulant experience.
Timestamps:
02:10 - Introducing the LAC
04:47 - What's in a name - nomenclature issues
07:06 - LACs and the APTT
11:31 - Testing for Lupus Anticoagulants
16:55 - LAC testing and anticoagulation
18:15 - Short Pre-Exam Cram Summary
20:10 - Hexagons are Bestagons
22:44 - Clinical Segue
28:00 - Some clinical features of APLS
31:51 - Episode Summary
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
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