
Orally Available Peptides With Kyal Van Der Leest
10/17/24 • 80 min
In this conversation, Lisa Tamati interviews Kyal Van Der Leest, a naturopath and formulator from Lvlup Health.
Kyal shares his personal journey, which began with his mother's cancer diagnosis, leading him to study nutrition and explore alternative therapies. The discussion covers the impact of hyperbaric oxygen therapy, the role of peptides in health, and the importance of quality sourcing in supplements.
Kyal also delves into the significance of zonulin in gut health and the effects of chronic inflammation on aging. In this conversation, Lisa Tamati and Kyal from LVLUP Health delve into the complexities of chronic inflammation, neuroprotective peptides, and the importance of effective detoxification strategies.
They discuss the role of liposomal delivery in enhancing peptide absorption, the significance of creatine and guanidinoacetic acid for brain health, and the intricate nature of methylation.
They also talk about liver health, detoxification pathways, binders, mold toxicity, the important of having strong barrier function in the gut and the blood brain barrier and cutting edge ingredients and molecules and peptides like:
- dihexa
- selank
- bpc-157
- TB500 fragments
- p21
- tudca
- binders
- globe artichoke
- NACET
- Guanoacetic acid
- Larozotike
- tribuytrin
- GHK-cu
- calcium d-glucarate
- and more
The conversation also touches on the challenges of research in natural supplements, the health implications of mould exposure, and the necessity of hormonal balance through proper testing and supplementation.
Takeaways:
- Kyal's journey into health began with his mother's cancer diagnosis.
- Hyperbaric oxygen therapy can be beneficial in cancer treatment.
- Peptides are naturally occurring compounds that have significant health benefits.
- Quality sourcing of peptides is crucial to avoid contaminants.
- Zonulin plays a key role in gut permeability and health.
- Chronic inflammation is linked to accelerated aging.
- Kyal emphasizes the importance of a metabolic approach to health.
- Innovative formulations can simplify health protocols for patients.
- The blood-brain barrier is critical for overall health.
- Understanding the connection between gut health and brain health is essential. Chronic inflammation markers provide insights into systemic health.
- Neuroprotective peptides can significantly enhance brain function.
- Liposomal delivery systems improve the bioavailability of peptides.
- Innovative products are emerging for neuroregeneration.
- Creatine and guanidinoacetic acid are vital for brain energy.
- Methylation processes are complex and require careful management.
- Supporting liver detoxification pathways is essential for health.
- Research on natural supplements is often limited and underfunded.
- Mould exposure can lead to serious health issues.
- Detoxification requires a comprehensive approach, not just diet.
Website: www.lvluphealth.com
Instagram: @lvluphealth
BIO
Kyal is a qualified Nutritionist and Naturopath with an obsession for health, fitness, functional medicine and human optimisation! Having worked in Health Food Stores, Gyms and Medical Clinics, Kyal has always been in the health field and has seen almost everything there is to see from varing perspectives - performance in the Gym, general health in the supplement store, and chronic illness at the medical clinic. Using this experience and his passion for supplementation and wellness, Kyal formulates LVLUP's products to serve very distinct purposes. Using only ingredients that scientifically and mechanistically makes sense, and what he knows WORKS from self-trial and self-experimentation so you can get the results that you pay for and expect!
Personalised Health Optimisation Consulting with Lisa Tamati
Lisa offers solution focused coaching sessions to help you find the right answers to your challenges.
Topics Lisa can help with:
Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach.
She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking.
She has extensive knowledge on such therapies as hyperbaric oxygen, intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional medicine testing.
Testing Options
- Comprehensive Thyroid testing
- DUTCH Hormone testi...
In this conversation, Lisa Tamati interviews Kyal Van Der Leest, a naturopath and formulator from Lvlup Health.
Kyal shares his personal journey, which began with his mother's cancer diagnosis, leading him to study nutrition and explore alternative therapies. The discussion covers the impact of hyperbaric oxygen therapy, the role of peptides in health, and the importance of quality sourcing in supplements.
Kyal also delves into the significance of zonulin in gut health and the effects of chronic inflammation on aging. In this conversation, Lisa Tamati and Kyal from LVLUP Health delve into the complexities of chronic inflammation, neuroprotective peptides, and the importance of effective detoxification strategies.
They discuss the role of liposomal delivery in enhancing peptide absorption, the significance of creatine and guanidinoacetic acid for brain health, and the intricate nature of methylation.
They also talk about liver health, detoxification pathways, binders, mold toxicity, the important of having strong barrier function in the gut and the blood brain barrier and cutting edge ingredients and molecules and peptides like:
- dihexa
- selank
- bpc-157
- TB500 fragments
- p21
- tudca
- binders
- globe artichoke
- NACET
- Guanoacetic acid
- Larozotike
- tribuytrin
- GHK-cu
- calcium d-glucarate
- and more
The conversation also touches on the challenges of research in natural supplements, the health implications of mould exposure, and the necessity of hormonal balance through proper testing and supplementation.
Takeaways:
- Kyal's journey into health began with his mother's cancer diagnosis.
- Hyperbaric oxygen therapy can be beneficial in cancer treatment.
- Peptides are naturally occurring compounds that have significant health benefits.
- Quality sourcing of peptides is crucial to avoid contaminants.
- Zonulin plays a key role in gut permeability and health.
- Chronic inflammation is linked to accelerated aging.
- Kyal emphasizes the importance of a metabolic approach to health.
- Innovative formulations can simplify health protocols for patients.
- The blood-brain barrier is critical for overall health.
- Understanding the connection between gut health and brain health is essential. Chronic inflammation markers provide insights into systemic health.
- Neuroprotective peptides can significantly enhance brain function.
- Liposomal delivery systems improve the bioavailability of peptides.
- Innovative products are emerging for neuroregeneration.
- Creatine and guanidinoacetic acid are vital for brain energy.
- Methylation processes are complex and require careful management.
- Supporting liver detoxification pathways is essential for health.
- Research on natural supplements is often limited and underfunded.
- Mould exposure can lead to serious health issues.
- Detoxification requires a comprehensive approach, not just diet.
Website: www.lvluphealth.com
Instagram: @lvluphealth
BIO
Kyal is a qualified Nutritionist and Naturopath with an obsession for health, fitness, functional medicine and human optimisation! Having worked in Health Food Stores, Gyms and Medical Clinics, Kyal has always been in the health field and has seen almost everything there is to see from varing perspectives - performance in the Gym, general health in the supplement store, and chronic illness at the medical clinic. Using this experience and his passion for supplementation and wellness, Kyal formulates LVLUP's products to serve very distinct purposes. Using only ingredients that scientifically and mechanistically makes sense, and what he knows WORKS from self-trial and self-experimentation so you can get the results that you pay for and expect!
Personalised Health Optimisation Consulting with Lisa Tamati
Lisa offers solution focused coaching sessions to help you find the right answers to your challenges.
Topics Lisa can help with:
Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach.
She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking.
She has extensive knowledge on such therapies as hyperbaric oxygen, intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional medicine testing.
Testing Options
- Comprehensive Thyroid testing
- DUTCH Hormone testi...
Previous Episode

Healing The Brain: A holistic Approach With Georgia Ferris
In this episode, Lisa Tamati discusses the complexities of brain injuries with her manager, Georgia Ferris. They explore various types of brain injuries, including traumatic and non-traumatic causes, and the importance of recognizing past injuries that may affect current health. The conversation delves into diagnostic methods, the role of nutrition, particularly the benefits of a ketogenic diet, and the significance of peptides and hyperbaric oxygen therapy in rehabilitation. Lisa emphasizes the need for lifestyle changes, including exercise and sleep hygiene, to support brain health and recovery
Takeaways
- Brain injuries can be traumatic or non-traumatic, affecting many aspects of health.
- Many people may not recognize past brain injuries that impact their current health.
- Diagnostic methods for brain injuries include scans and hormone testing.
- Nutrition plays a crucial role in brain rehabilitation, with a focus on whole foods.
- The ketogenic diet can provide an alternative energy source for the brain.
- Peptides are emerging as a significant treatment for brain recovery.
- Hyperbaric oxygen therapy can reduce inflammation and promote healing.
- Lifestyle changes, including exercise and sleep, are vital for brain health.
- Environmental toxins can contribute to neuroinflammation and brain injuries.
- A holistic approach is necessary for effective brain injury recovery.
Personalised Health Optimisation Consulting with Lisa Tamati
Lisa offers solution focused coaching sessions to help you find the right answers to your challenges.
Topics Lisa can help with:
Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach.
She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking.
She has extensive knowledge on such therapies as hyperbaric oxygen, intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional medicine testing.
Testing Options
- Comprehensive Thyroid testing
- DUTCH Hormone testing
- Adrenal Testing
- Organic Acid Testing
- Microbiome Testing
- Cell Blueprint Testing
- Epigenetics Testing
- DNA testing
- Basic Blood Test analysis
- Heavy Metals
- Nutristat
- Omega 3 to 6 status
and more
Lisa and her functional medicine colleagues in the practice can help you navigate the confusing world of health and medicine .
She can also advise on the latest research and where to get help if mainstream medicine hasn't got the answers you are searching for whatever the challenge you are facing from cancer to gut issues, from depression and anxiety, weight loss issues, from head injuries to burn out to hormone optimisation to the latest in longevity science. Book your consultation with Lisa
Join our Patron program and support the show
Pushing the Limits' has been free to air for over 8 years. Providing leading edge information to anyone who needs it. But we need help on our mission.
Please join our patron community and get exclusive member benefits (more to roll out later this year) and support this educational platform for the price of a coffee or two
You can join by going to Lisa's Patron Community
Or if you just want to support Lisa with a "coffee" go to
https://www.buymeacoffee.com/LisaT to donate $3
Lisa’s Anti-Aging and Longevity Supplements
Lisa has spent years curating a very specialized range of exclusive longevity, health optimizing supplements from leading scientists, researchers and companies all around the world.
This is an unprecedented collection. The stuff Lisa wanted for her family but couldn't get in NZ that’s what it’s in her range. Lisa is constantly researching and interviewing the top scientists and researchers in the world to get you the best cutting edge supplements to optimize your life.
Subscribe to our popular Youtube channel
with over 600 videos, millions of views, a number of full length documentaries, and much more. You don't want to miss out on all the great content on our Lisa's youtube channel.
Order Lisa's Books
Lisa has published 5 books: Running Hot, Running to Extremes, Relentless, What your oncologist isn't telling you...
Next Episode

Unlocking The Secrets Of Metabolic Health With DAHLIA4 With Professor Alex Tups
In this conversation, Professor Alex Tups discusses his extensive research on metabolic regulation, focusing on the roles of leptin and insulin in the brain. He shares insights into the discovery of butane, a compound found in the Dahlia flower, and its potential to improve blood sugar regulation and combat neuroinflammation. The discussion highlights the importance of diet, gut health, and the synergistic effects of flavonoids in promoting overall well-being. Professor Tups emphasizes the need for further research and clinical trials to validate the benefits of his findings. In this conversation, Alexander Tups and Lisa Tamati discuss the journey of research from the lab to market, focusing on the supplement Dahlia 4 and its potential impact on health, particularly in relation to metabolic dysregulation and neuroinflammation. They explore the importance of consumer awareness regarding supplements, the role of circadian rhythms in health, and the need for proactive health measures. The discussion emphasizes the unique mechanism of Dahlia 4 in targeting brain inflammation and its implications for conditions like Alzheimer's disease.
Takeaways:
- Leptin and insulin play crucial roles in metabolic regulation.
- Neuroinflammation is a key factor in insulin resistance.
- Dahlia4 is a supplement derived from the Dahlia flower.
- Flavonoids can have synergistic effects on health.
- Diet and gut health significantly impact overall well-being.
- Research shows potential for reversing pre-diabetes.
- Oral hygiene is linked to brain health.
- Clinical trials are ongoing for Dahlia 4's effectiveness.
- The brain is a master organ in regulating metabolism.
- Natural compounds can have varying effects on health. The importance of feedback from users to improve health products.
- Research must translate into real-world applications for maximum impact.
- Basic research is crucial for developing new drugs and supplements.
- Supplements can be brought to market faster than traditional drugs.
- Consumer awareness is key in choosing effective supplements.
- Metabolic dysregulation is a growing concern for aging populations.
- Neuroinflammation may be addressed with targeted supplements.
- Regular eating patterns can support circadian rhythms and metabolic health.
- Dahlia4 targets brain inflammation, offering a unique approach.
- Proactive health measures can mitigate risks of chronic diseases.
If you would like to try DAHLIA4 you can now find it in our range at www.lisatamati.com Dahlia4
BIO
Alexander Tups pursued his academic journey in Biology, initially studying at the Heinrich Heine University of Duesseldorf and the Philipps University of Marburg. He earned a Diploma in Biology at the latter institution, focusing on Animal Physiology, Genetics, and Developmental Biology. He further advanced his education through a Marie Curie and Boehringer Ingelheim Fonds Scholarship, undertaking a Ph.D. at the Rowett Research Institute, one of the UK's leading nutrition research centres and the Philipps University of Marburg. In 2005 he graduated with "summa cum laude (highest distinction) " for his research on the neuroendocrine mechanism that regulates seasonal body weight. Following his Ph.D., Alexander Tups served as a postdoctoral fellow at the University of Otago from 2006-2008. In recognition of his potential, he received a prestigious junior group leader grant in nutrition research from the German Ministry of Education and Research in 2007, amounting to €1,500,000. This grant allowed him to establish an independent research group called 'neuronal nutrition physiology' at the Philipps University of Marburg, where he explored the impact of nutrient sensing in the brain on the regulation of body weight and glucose homeostasis as one of the youngest independent group leaders in Germany. From 2012-2014 in addition to his group leader role he was Head of Department for Animal Physiology at this institution before he was appointed at the University of Otago in 2014 in Physiology. Throughout his career, Alex Tups has contributed significantly to his field, publishing 48 peer reviewed research papers, the vast majority as lead author. His research has contributed to our understanding of how the brain controls body weight and blood sugar levels. His work has been internationally recognized with notable awards, such as the Michael Harbuz Price in neuroendocrine research in the UK in 2009, the Ernst and Berta Sharrer Award in Germany in 2014, the Commercialisation Researcher Award at Otago University in 2023 and the Research Excellence Price by the Physiological Society of New Zealand in 2023. Alexander revie...If you like this episode you’ll love
Episode Comments
Generate a badge
Get a badge for your website that links back to this episode
<a href="https://goodpods.com/podcasts/pushing-the-limits-398827/orally-available-peptides-with-kyal-van-der-leest-76489294"> <img src="https://storage.googleapis.com/goodpods-images-bucket/badges/generic-badge-1.svg" alt="listen to orally available peptides with kyal van der leest on goodpods" style="width: 225px" /> </a>
Copy