Pushing The Limits

In this eye-opening episode, we dive deep into the world of post-concussion syndrome (PCS) and brain health with Dr. Mark Allen of Cognitive FX, a leading expert in brain repair. PCS affects millions worldwide, yet many are left frustrated with lingering symptoms like brain fog, fatigue, and headaches. Dr. Allen shares his groundbreaking approach that combines the latest in neuroscience with a holistic, multidisciplinary method to treat and heal the brain.

Key topics include:

• Why Functional MRI (fMRI) is a Game Changer: How it identifies hidden brain dysfunction and tailors treatments to individual needs.
• Integrated Healing Strategies: From vestibular rehabilitation and neuromuscular therapy to high-intensity interval training (HIIT) programs designed for the brain.
• Cognitive and Sensory Therapy: Rewiring the brain through targeted cognitive tasks and sensory integration work.
• The Role of Neurointegration and Occupational Therapy: Enhancing brain-body connections for long-term recovery.
• Timely Treatment vs. Old Injuries: Why starting treatment early yields the best results, but even years-old injuries can still benefit significantly from intervention.

Dr. Allen explains how this multifaceted approach not only addresses symptoms but helps restore overall brain function, enabling patients to return to their lives with clarity, focus, and vitality.

Whether you're dealing with a recent injury or have struggled with PCS for years, this episode is a must-watch for anyone seeking answers and actionable solutions.

🤝 Connect with Dr. Mark Allen: Learn more about Dr. Mark Allen's expertise in cognitive rehabilitation and neuroplasticity by visiting his website. Explore his latest insights and groundbreaking approaches to improving brain health and function.

🌐 Website: cognitivefxusa.com BIO

Co-Founder, Neuroscientist

Mark D. Allen earned a PhD in Cognitive Science at Johns Hopkins University with post-doctoral training in Cognitive Neuroscience and Functional Neuroimaging at the University of Washington. As a cofounder, Dr. Allen developed the scientific foundation and technological innovations that make treatment at Cognitive Fx unique and exceptional. Dr. Allen is a pioneer in the development of fMRI for use in clinical settings.

Significant scientific contributions include the development of neuroimaging biomarkers for post-concussion diagnosis and treatment and theoretical work in the pathophysiology of chronic post-concussion symptoms. Specifically, his research led to the discovery of the key role of neurovascular coupling dysfunction in post-concussion syndrome. Significant clinical contributions include fMRI patient assessment based on individual neuroanatomy analysis—he has performed over 10,000 such assessments to date.

Additional clinical contributions include the development of a unique high intensity interval training protocol of cardiovascular exercise that targets restoration of neuronal function and cerebrovascular responsivity. Most recently, Dr, Allen has co-engineered a machine learning-based program for functional neuroanatomical discovery, and highly advanced fMRI analysis techniques which provide a more reliable and standardized method of fMRI analysis on concussion patients.

🎯 Personalised Health Optimisation Consulting with Lisa Tamati

Lisa offers solution focused coaching sessions to help you find the right answers to your challenges.

📌 Topics Lisa can help with:

Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach.

She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking.

She has extensive knowledge on such therapies as hyperbaric oxygen, intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional medicine testing.

🔬 Testing Options

• Comprehensive Thyroid testing
• DUTCH Hormone testing
• Adrenal Testing
• Organic Acid Testing
• Microbiome Testing
• Cell Blueprint Testing
• Epigenetics Testing
• DNA testing
• Basic Blood Test analysis
• Heavy Metals
• Nutristat
• Omega 3 to 6 status

and more

Lisa and her functional medicine colleagues in the practice can help you navigate the confusing world of health and medicine .

She can also advise on the latest research and where to get help if mainstream medicine hasn't got the answers you are searching for whatever the challenge you are facing from cancer to gut issues, from depression and anxiety, weight loss ...

In this conversation, Lisa Tamati interviews Kyal Van Der Leest, a naturopath and formulator from Lvlup Health.

Kyal shares his personal journey, which began with his mother's cancer diagnosis, leading him to study nutrition and explore alternative therapies. The discussion covers the impact of hyperbaric oxygen therapy, the role of peptides in health, and the importance of quality sourcing in supplements.

Kyal also delves into the significance of zonulin in gut health and the effects of chronic inflammation on aging. In this conversation, Lisa Tamati and Kyal from LVLUP Health delve into the complexities of chronic inflammation, neuroprotective peptides, and the importance of effective detoxification strategies.

They discuss the role of liposomal delivery in enhancing peptide absorption, the significance of creatine and guanidinoacetic acid for brain health, and the intricate nature of methylation.

They also talk about liver health, detoxification pathways, binders, mold toxicity, the important of having strong barrier function in the gut and the blood brain barrier and cutting edge ingredients and molecules and peptides like:

• dihexa
• selank
• bpc-157
• TB500 fragments
• p21
• tudca
• binders
• globe artichoke
• NACET
• Guanoacetic acid
• Larozotike
• tribuytrin
• GHK-cu
• calcium d-glucarate
• and more

The conversation also touches on the challenges of research in natural supplements, the health implications of mould exposure, and the necessity of hormonal balance through proper testing and supplementation.

Takeaways:

• Kyal's journey into health began with his mother's cancer diagnosis.
• Hyperbaric oxygen therapy can be beneficial in cancer treatment.
• Peptides are naturally occurring compounds that have significant health benefits.
• Quality sourcing of peptides is crucial to avoid contaminants.
• Zonulin plays a key role in gut permeability and health.
• Chronic inflammation is linked to accelerated aging.
• Kyal emphasizes the importance of a metabolic approach to health.
• Innovative formulations can simplify health protocols for patients.
• The blood-brain barrier is critical for overall health.
• Understanding the connection between gut health and brain health is essential. Chronic inflammation markers provide insights into systemic health.
• Neuroprotective peptides can significantly enhance brain function.
• Liposomal delivery systems improve the bioavailability of peptides.
• Innovative products are emerging for neuroregeneration.
• Creatine and guanidinoacetic acid are vital for brain energy.
• Methylation processes are complex and require careful management.
• Supporting liver detoxification pathways is essential for health.
• Research on natural supplements is often limited and underfunded.
• Mould exposure can lead to serious health issues.
• Detoxification requires a comprehensive approach, not just diet.

Website: www.lvluphealth.com

Instagram: @lvluphealth

BIO

Kyal is a qualified Nutritionist and Naturopath with an obsession for health, fitness, functional medicine and human optimisation! Having worked in Health Food Stores, Gyms and Medical Clinics, Kyal has always been in the health field and has seen almost everything there is to see from varing perspectives - performance in the Gym, general health in the supplement store, and chronic illness at the medical clinic. Using this experience and his passion for supplementation and wellness, Kyal formulates LVLUP's products to serve very distinct purposes. Using only ingredients that scientifically and mechanistically makes sense, and what he knows WORKS from self-trial and self-experimentation so you can get the results that you pay for and expect!

Personalised Health Optimisation Consulting with Lisa Tamati

Lisa offers solution focused coaching sessions to help you find the right answers to your challenges.

Topics Lisa can help with:

Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach.

She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking.

She has extensive knowledge on such therapies as hyperbaric oxygen, intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional medicine testing.

Testing Options

• Comprehensive Thyroid testing
• DUTCH Hormone testi...

In this weeks episode, world renown Vitamin E researcher and also GG researcher, author and founder of American River Nutrition is today's illustrious guest, Dr Barrie Tan.

The information you will learn from todays episode - if you take it onboard, will indeed change your life, longevity and health for the better so this is a must listen to podcast with actionable insights and incredible clinical research behind it.

What you will learn:

• Who is Dr. Barrie Tan?.
• What is Vitamin E - Tocotrienol?
• What is GG?
• What is the difference between tocotrienol and GG?
• What is the difference between tocotrienol and tocopherol?
• Which annatto should you take?
• What is the link between CoQ10 and statins and GG.
• What is the link between GG and testosterone?
• Why should you take MK-4 and GG?...

Tocotrienols roles in bone density

Tocotrienols roles in Non alcoholic fatty liver disease, pre diabetes, diabetes, cardiovascular disease

Tocotrienols role in fighting various cancer types

GG's role in bone density, muscle synthesis, coenzyme Q10 absorption and much much more.

website https://barrietan.com/ Riverside Nutrition his manufacturing company - The research mentioned in this show is available at https://americanrivernutrition.com/

If you want to get GG, Tocotrienols or Coqnol (Coenzyme Q10 with GG), you can reach us out directly through our email [email protected] and we can organize that.

BIO

A scientist first and foremost, Dr. Tan earned his Ph.D. in chemistry/biochemistry from the University of Otago, New Zealand, and spent several years as a professor at UMass. Dr. Tan has committed himself to the research and development of phytonutrients — natural compounds found in plants that reduce and slow chronic disorders.

Dr. Barrie Tan is hailed as a trailblazer and the world's foremost expert on vitamin E, credited with discovering tocotrienol in three major natural sources and geranylgeraniol, an essential nutrient with implications for sports and active nutrition. A scientist first and foremost, Dr. Tan earned his Ph.D. in Chemistry/Biochemistry from the University of Otago, New Zealand and spent several years as a professor at UMass. Today, his research focuses on lipid-soluble nutrients that reduce and slow chronic conditions.

Dr. Tan is credited with discovering a form of vitamin E called tocotrienol from three major sources: palm, rice, and annatto — a natural dye and food coloring derived from the seeds of the achiote tree, known for its potential health benefits, including antioxidant and antimicrobial properties. Editor of two prestigious books on tocotrienol and founder of the International Tocotrienol Conference, Dr. Tan was dubbed the "Tocotrienol King" by Dr. Stephen Sinatra, a highly respected and sought-after cardiologist.

Dr. Tan has held roles of Chief Scientific Officer and Scientific Board Member for multinational organizations. His career includes periods working in association with the US Armed Forces and a Prince of Thailand. He has successfully launched multiple businesses in the nutrition industry and owns an array of patents and intellectual property, keeping him at the forefront of scientific innovation.

He is an internationally celebrated and sought-after speaker, having presented at multiple respected conferences in the field including; IFT, ADA, ASN, IHS, A4M, NPA, AACR, ICIM, IAOMT, and the Academy of Nutrition and Dietetics.

Dr. Tan is currently the President of American River Nutrition, a natural health R&D company he started with his wife, Elizabeth, in 1998. Described as a scientific pioneer, his mission is simple: improve the everyday health of people's lives through the rigorous application of DeltaGold® – the first-ever tocopherol-free tocotrienol product extracted from annatto, and the most potent form of vitamin E in existence today.

As for links, we'd love to give people a free copy of his eBook The Truth About Vitamin E which can be found at https://barrietan.com/book/ using code: Pushing The Limits

Personalised Health Optimisation Consulting with Lisa Tamati

Lisa offers solution focused coaching sessions to help you find the right answers to your challenges.

Topics Lisa can help with:

Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach.

She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking.

She has extensive knowledge on such therapies as hyperbaric oxygen, intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional me...

In this fascinating first instalment of a three-part series, we dive deep into the groundbreaking world of telomere science with Dr. Bill Andrews, a pioneering researcher in the field of ageing and longevity. Known for his revolutionary work on telomeres and their role in cellular aging, Dr. Andrews shares insights into how his research is paving the way for the ultimate goal: curing aging.

Dr. Andrews, the founder of Sierra Sciences, has dedicated his life to understanding the root causes of ageing at the molecular level. This episode covers the basics of telomeres, the science behind their shortening, and why maintaining telomere length is essential for longevity and disease prevention.

Key Discussion Points:

1. What Are Telomeres?
   • Telomeres are protective caps at the ends of chromosomes that safeguard our genetic material during cell division.
   • As we age, telomeres shorten, leading to cellular dysfunction and ageing.
2. Why Telomeres Matter in Aging:
   • Telomere shortening is a major driver of ageing and age-related diseases.
   • Dr. Andrews explains the link between telomeres and cellular senescence, inflammation, and chronic illnesses.
3. Dr. Bill Andrews' Mission:
   • The story behind Sierra Sciences, a biotechnology company dedicated to discovering drugs that activate the telomerase enzyme.
   • Telomerase can rebuild and lengthen telomeres, potentially reversing cellular aging.
4. The Science of Telomerase Activation:
   • Current progress in identifying compounds that safely activate telomerase.
   • Challenges and breakthroughs in the quest to develop anti-ageing therapies.
5. Ethics and Implications of Curing Aging:
   • Dr. Andrews discusses the societal, ethical, and philosophical implications of extending human lifespan.
   • Addressing misconceptions about anti-ageing science.

What You Will Learn:

• The fundamental role of telomeres in ageing and disease.
• How telomerase activation could revolutionise health and longevity.
• The current state of telomere research and its future potential.
• The challenges and ethical questions surrounding anti-ageing technologies.

Don’t miss the next episode in this series, where Dr. Andrews delves deeper into telomerase activation and the latest breakthroughs in curing aging. Subscribe to "Pushing the Limits" and share this episode with anyone passionate about health, science, and longevity!

Bio:

Dr. Bill Andrews is a molecular biologist, inventor, and renowned expert in the field of telomere science. He has over three decades of experience in biotech, including significant contributions to telomerase research. Dr. Andrews holds over 50 U.S. patents related to telomerase activation and has authored numerous scientific papers. Through his work at Sierra Sciences, he aims to unlock the secrets of human longevity and help people live healthier, longer lives.

As a scientist, athlete, and executive, Bill continually pushes the envelope and challenges convention. He has been featured in Popular Science, The Today Show, and numerous documentaries on the topic of life extension including, most recently, the movie The Immortalists in which he co-stars with Dr. Aubrey de Grey.

Bill has been a medical researcher in biotech since 1981, focusing on cancer, heart disease, and inflammation research, though his passion has always been ageing. In the early-to-mid 1990s, while at Geron Corporation, Bill led the research to discover both the RNA and protein components of the human enzyme called telomerase. This enzyme is responsible for preventing telomeres from shortening in human reproductive cells, and this is why our children are born younger than we are even though they come from our old cells. Inducing this enzyme to lengthen telomeres in all our cells, not just our reproductive cells, to reverse aging and declining health due to aging, is the principal goal of Sierra Sciences and Sierra Holdings.

Website: https://sierrasci.com/

The Immortalists Movie: https://theimmortalists.com/watch/

Best Choice Medicine petition, that you can sign today: https://www.bestchoicemedicine.com/

🎯 Personalised Health Optimisation Consulting with Lisa Tamati

Lisa offers solution focused coaching sessions to help you find the right answers to your challenges.

📌 Topics Lisa can help with:

Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach.

She is a qualified Ph360 Epigenetics coach and a clinician with The...

Welcome back to the second part of the Aevum Labs Series on Immune Health!

In this episode, we sit down with Dr. Elizabeth Yurth, founder of the Boulder Longevity Institute, to explore the fascinating world of immunosenescence—the ageing of the immune system—and its connection to inflammaging, chronic inflammation that accelerates aging. Dr. Yurth explains how the decline of our immune system not only affects our resilience to infections but also plays a pivotal role in the development of chronic diseases, neurodegeneration, and overall cellular decline.

We dive into how gut health, immune health, and cellular health are deeply interconnected, with 70–80% of our immune system residing in and around the gut. Learn how chronic systemic inflammation and gut permeability can break down your immune defenses and how you can turn back the clock on immune ageing.

We also introduce our exciting new product developed in conjunction with Dr Yurth as a scientific advisor, from Aevum Labs—Rejuvenate—which is specifically designed to target immune decline, support cellular health, and reduce chronic inflammation. Dr. Yurth explains how the ingredients in Rejuvenate help restore immune vitality, protect brain health, and improve gut barrier integrity.

Key Topics Discussed:

• What is immunosenescence? Understanding how and why our immune system declines with age.
• The link between chronic systemic inflammation (inflammaging) and ageing—why targeting inflammation is essential for longevity.
• The gut-immune connection: Why 70–80% of your immune system resides in the gut and how gut health affects brain health and systemic inflammation.
• Practical strategies to combat immune aging, from diet and lifestyle interventions to cutting-edge supplements.

🧬✨The Role of Rejuvenate in Fighting Immunosenescence and Inflammaging

💡Shop Now: Re:juvenate Pro by Aevum Labs

💡Find Out More: Aevum Labs Website | Aevum Labs Instagram

Rejuvenate, the flagship product from Aevum Labs, is formulated to help slow the decline of the immune system by addressing chronic inflammation, improving gut barrier health, and supporting cellular repair.

🌱 Key Ingredients and Their Benefits:

1. Immune Defense Protein (IDP) – Produced by Quantec, this innovative bioactive protein has powerful immune-modulating properties. IDP works to restore and strengthen the gut barrier, which is critical for maintaining immune balance. It also reduces gut inflammation and supports a healthy gut microbiome, which in turn improves immune resilience. Listen here to learn more about IDP: Dr Rod Claycomb co-founder of Quantec Ltd
2. Immunel® (Concentrated Colostrum) – Sourced from Sterling Technology, Immunel is a concentrated colostrum extract rich in natural immune peptides and growth factors. These components stimulate immune activity and help rejuvenate the aging immune system, providing rapid immune support.
3. Carnosic Acid (Rosemary Extract) – A potent antioxidant and neuroprotective compound that reduces inflammation and oxidative stress. Carnosic acid also supports brain health, helping to protect against age-related cognitive decline while reducing systemic inflammation.
4. Kawakawa (Piper excelsum) – A traditional New Zealand medicinal plant, kawakawa is known for its anti-inflammatory and gut-soothing properties. It supports gut barrier health, reduces chronic inflammation, and promotes overall immune balance.

🌱 How Rejuvenate Supports Whole-Body Health

• Cellular Health: Reduces oxidative stress and inflammation, promoting cellular repair and longevity.
• Gut Health: Strengthens the gut barrier and balances the microbiome, reducing gut permeability (leaky gut) and inflammation.
• Immune Health: Supports both the innate and adaptive immune system, helping restore immune balance and preventing chronic immune fatigue.
• Brain Health: Carnosic acid and immune-modulating peptides help protect against neuroinflammation and support cognitive function.

🌱 Why Immune Health Matters for Longevity

Dr. Yurth emphasiaes that immune health is the foundation of longevity. By reducing systemic inflammation and restoring immune resilience, you can not only extend your lifespan but also improve your healthspan—ensuring your later years are vibrant and disease-free.

Don’t miss this deep dive into the science of aging and immune optimisation! Learn how cutting-edge ...