
Exploring Anti-aging & Integrative Medicine: Hormones, Thyroid Health, Brain Injuries, and More with Dr. Bill Clearfield
08/01/24 • 93 min
Join us in this enlightening episode as we sit down with Dr. Bill Clearfield from Clearfield Medical Group to explore the intricacies of integrative medicine. Dr. Clearfield shares his expert insights on a range of topics, including hormone health, thyroid disorders, brain injuries, the potential of methylene blue, low-dose naltrexone, and the impacts of COVID-19 and long COVID. Whether you're seeking to understand hormone replacement therapy or looking for effective treatments for long COVID, this episode is packed with valuable information.
Topics Covered:Hormones
- The role of hormones in maintaining overall health and well-being
- Benefits and risks of hormone replacement therapy for both men and women
- Differences and advantages of bioidentical hormones versus synthetic hormones
- Common hormonal imbalances and how they are addressed in practice
Thyroid Health
- Common thyroid disorders and their impact on overall health
- Key thyroid function tests for accurate diagnosis
- Influence of thyroid health on weight management and metabolism
- Natural or integrative approaches to managing thyroid conditions
Brain Injuries
- Latest advancements in the treatment of traumatic brain injuries (TBI)
- Importance of neuroplasticity in the recovery from brain injuries and methods to enhance it
- Integrative therapies recommended for brain injury recovery
Methylene Blue
- Explanation of methylene blue and its primary medical uses
- Current evidence on methylene blue's effectiveness in treating viral infections
- Potential use of methylene blue to support brain health and cognitive function
Low Dose Naltrexone (LDN)
- Overview of low dose naltrexone and conditions it can help manage
- Mechanism of action of LDN and its therapeutic effects
- Success stories or case studies where LDN has made a significant impact
General Topics
- Differences and benefits of integrative medicine compared to conventional medicine
- Approach to patient care to ensure personalized and effective treatment
- Future trends in medicine and healthcare that excite Dr. Clearfield
- Clearfield Medical Group
- Dr. Bill Clearfield's LinkedIn
- Follow Dr. Clearfield on Facebook
- Learn More About Integrative Medicine
BIO
With 33 years of medical experience, Reno, Nevada physician, William Clearfield, D.O. of the Clearfield Medical Group provides patients with successful treatment plans that benefit their health conditions and boost their overall quality of life.
Emphasizing diet, exercise and a healthy lifestyle, Dr. Clearfield was the “go to” guy when other physicians, even specialists at NYU and the University of Pennsylvania were baffled, in his adopted hometown of Wilkes-Barre, Pa.
Dr. Clearfield graduated from the College of Osteopathic Medicine and Surgery, now Des Moines University, in 1978. He interned at Metropolitan Hospital in downtown Philadelphia and followed that up with a residency in Obstetrics and Gynecology and Family Medicine.
In 1984 he tested and successfully implemented one of the first individualized computer generated diet programs (on an Apple IIc no less) and instituted the Medifast Protein Sparing Modified Weight Loss program at Nesbitt Memorial Hospital in Kingston, Pa.
In 1990, a curious combination of family events, a cousin who, after ten years of fertility issues, became pregnant after three sessions, and a chance encounter with a ninety-year-old practitioner from the Peoples Republic of China, on a trip back home, led him to UCLA’s Medical Acupuncture Physicians training.
Dr. C. took to acupuncture quickly, becoming the second medical doctor in the Wilkes, Barre-Scranton area to offer acupuncture in his practice. He became. Elected to the board of directors as the education director of the American Academy of Medical Acupuncture in 1992, Dr. C began a student with experienced acupuncturists which continue to this day.
After election as the Secretary of the American Academy of Medical Acupuncture in 1994, Dr. C obtained his most prized academic degree. The secretary of the AAMA signed the diplomas earned in that session. In short, Dr. Clearfield signed his diploma!
His 1992 treatise “Celestial Stems-5 Element Diet an...
Join us in this enlightening episode as we sit down with Dr. Bill Clearfield from Clearfield Medical Group to explore the intricacies of integrative medicine. Dr. Clearfield shares his expert insights on a range of topics, including hormone health, thyroid disorders, brain injuries, the potential of methylene blue, low-dose naltrexone, and the impacts of COVID-19 and long COVID. Whether you're seeking to understand hormone replacement therapy or looking for effective treatments for long COVID, this episode is packed with valuable information.
Topics Covered:Hormones
- The role of hormones in maintaining overall health and well-being
- Benefits and risks of hormone replacement therapy for both men and women
- Differences and advantages of bioidentical hormones versus synthetic hormones
- Common hormonal imbalances and how they are addressed in practice
Thyroid Health
- Common thyroid disorders and their impact on overall health
- Key thyroid function tests for accurate diagnosis
- Influence of thyroid health on weight management and metabolism
- Natural or integrative approaches to managing thyroid conditions
Brain Injuries
- Latest advancements in the treatment of traumatic brain injuries (TBI)
- Importance of neuroplasticity in the recovery from brain injuries and methods to enhance it
- Integrative therapies recommended for brain injury recovery
Methylene Blue
- Explanation of methylene blue and its primary medical uses
- Current evidence on methylene blue's effectiveness in treating viral infections
- Potential use of methylene blue to support brain health and cognitive function
Low Dose Naltrexone (LDN)
- Overview of low dose naltrexone and conditions it can help manage
- Mechanism of action of LDN and its therapeutic effects
- Success stories or case studies where LDN has made a significant impact
General Topics
- Differences and benefits of integrative medicine compared to conventional medicine
- Approach to patient care to ensure personalized and effective treatment
- Future trends in medicine and healthcare that excite Dr. Clearfield
- Clearfield Medical Group
- Dr. Bill Clearfield's LinkedIn
- Follow Dr. Clearfield on Facebook
- Learn More About Integrative Medicine
BIO
With 33 years of medical experience, Reno, Nevada physician, William Clearfield, D.O. of the Clearfield Medical Group provides patients with successful treatment plans that benefit their health conditions and boost their overall quality of life.
Emphasizing diet, exercise and a healthy lifestyle, Dr. Clearfield was the “go to” guy when other physicians, even specialists at NYU and the University of Pennsylvania were baffled, in his adopted hometown of Wilkes-Barre, Pa.
Dr. Clearfield graduated from the College of Osteopathic Medicine and Surgery, now Des Moines University, in 1978. He interned at Metropolitan Hospital in downtown Philadelphia and followed that up with a residency in Obstetrics and Gynecology and Family Medicine.
In 1984 he tested and successfully implemented one of the first individualized computer generated diet programs (on an Apple IIc no less) and instituted the Medifast Protein Sparing Modified Weight Loss program at Nesbitt Memorial Hospital in Kingston, Pa.
In 1990, a curious combination of family events, a cousin who, after ten years of fertility issues, became pregnant after three sessions, and a chance encounter with a ninety-year-old practitioner from the Peoples Republic of China, on a trip back home, led him to UCLA’s Medical Acupuncture Physicians training.
Dr. C. took to acupuncture quickly, becoming the second medical doctor in the Wilkes, Barre-Scranton area to offer acupuncture in his practice. He became. Elected to the board of directors as the education director of the American Academy of Medical Acupuncture in 1992, Dr. C began a student with experienced acupuncturists which continue to this day.
After election as the Secretary of the American Academy of Medical Acupuncture in 1994, Dr. C obtained his most prized academic degree. The secretary of the AAMA signed the diplomas earned in that session. In short, Dr. Clearfield signed his diploma!
His 1992 treatise “Celestial Stems-5 Element Diet an...
Previous Episode

Unlocking The Healing Potential Of Aloe Polysaccharides With Dr John Lewis
In this episode, we sit down with Dr. John Lewis, a leading expert in nutritional research and the therapeutic potential of Aloe polysaccharides. Dr. Lewis shares insights from his groundbreaking studies on Alzheimer's disease, multiple sclerosis (MS), and the broader impacts of Aloe polysaccharides on immune function and brain health.
Key Topics Discussed
- Understanding Aloe Polysaccharides
- What are Aloe polysaccharides?
- How are they extracted and formulated for nutritional supplements?
- Research on Alzheimer's Disease and Multiple Sclerosis
- Overview of Dr. Lewis's studies on Alzheimer's disease and MS.
- Impact of Aloe polysaccharides on cognitive function and disease progression.
- Immune System Modulation
- Effects of Aloe polysaccharides on CD4 to CD8 ratios.
- Regulation of key cytokines: TNF-alpha, VEGF, and BDNF.
- Balancing TH1 and TH2 responses.
- Brain Care Formulation
- Detailed discussion on the Brain Care formulation developed by Dr. Lewis.
- Clinical results and patient outcomes.
- Challenges in Nutritional Research
- Funding difficulties for nutritional and supplement research.
- Issues with the pharmacological model of placebo-controlled randomized double-blind trials.
- Why this model is challenging for evaluating supplements and nutritional interventions.
- Future Directions and Innovations
- Potential future applications of Aloe polysaccharides in other health conditions.
- Innovations in nutritional research methodologies.
Key Takeaways
- Aloe Polysaccharides: Naturally occurring compounds with significant therapeutic potential, particularly in modulating immune function and supporting brain health.
- Clinical Research: Dr. Lewis's studies highlight the positive effects of Aloe polysaccharides on Alzheimer's disease, MS, and overall immune health.
- Nutritional Research Challenges: The current pharmacological model of clinical trials poses challenges for the study of supplements, necessitating new research approaches.
Research References
- Studies on Alzheimer's disease and Aloe polysaccharides: Positive impacts on cognitive function and disease markers.
- Research on MS: Aloe polysaccharides and their role in managing symptoms and progression.
- Immune modulation: Detailed findings on CD4/CD8 ratios, cytokines (TNF-alpha, VEGF, BDNF), and TH1/TH2 balance.
Dr. John Lewis provides compelling evidence on the health benefits of Aloe polysaccharides and underscores the need for innovative research methodologies in nutritional science. This episode offers valuable insights for anyone interested in the intersection of nutrition, immune function, and brain health.Connect with Dr. John Lewis
- Website: Dr. John Lewis Nutrition
If you want to get Daily Brain Care visit our online curated range of cutting edge longevity and anti-aging supplements at
BIO
John E. Lewis, Ph.D. is the Founder and President of Dr Lewis NutritionTM.
Dr. John E. Lewis has spent most of his career developing a unique approach as someone who "walks the walk" through all of his combined professional and personal experiences to attaining optimal health through nutrition, dietary supplements, and exercise. Throughout his research career, he has evaluated many different nutritional approaches to enhancing well-being, particularly for brain health, immune function, and counteracting aging. He can separate fact from fiction regarding how to utilize nutrition and dietary supplements to help you achieve and maintain optimal health. If you need a trusted source of information, products, and services, then look no further than Dr. Lewis and how he can help you achieve your health-related goals.
Professional Career
Dr. Lewis is past full-time Associate Professor in the Department of Psychiatry and Behavioral Sciences at the University of Miami Miller School of Medicine and the Founder and President of Dr Lewis NutritionTM. He is a Diplomate, Faculty Member, and Advisor of the Medical Wellness Association. He has been the principal investigator of over 30 different studies on human health in his research career. During that time, he either directly raised or indirectly s...
Next Episode

Introducing 1-MNA: The New Longevity Molecule With Lisa Tamati
In this episode, we delve into a revolutionary longevity molecule that you might not have heard of before: 1-MNA. If you're interested in staying younger longer and if you want to maintain your energy and vitality then this is an episode for you.
Perhaps you have read the groundbreaking book by Dr David Sinclair "Lifespan" where he talks about NAD and how crucial it is for the body and how it can help upregulate sirtuin genes (longevity genes) and help you maintain your cellular health and energy. We are now 4 years on we have more data, studies and information to share in this arena.
Perhaps you have been trying to improve your NAD metabolism, taking NMN (nicotinamide mononucleotide) or NR (nicotinamide riboside), and upregulating sirtuin genes, if you have then you need to hear this.
We'll explore the intricacies of NAD pathways, the role of key enzymes, and why simply supplementing with NAD precursors may not be the best holistic approach and how we can improve on that approach to anti-aging
Key Points Discussed:
- Introduction to NAD Metabolism:
- Overview of previous episodes on NAD metabolism with experts like Professor Joseph Baur, Dr. Elizabeth Yurth from the Boulder Longevity Institute, and Dr. Elena Seranova.
- Importance of understanding the complexities of NAD pathways beyond the basics.
- Understanding 1-MNA:
- Explanation of 1-MNA and its role in controlling NAD levels by blocking the enzyme NNMT (Nicotinamide N-methyltransferase).
- The dangers of upregulating NNMT, which degrades NAD and can lead to various health issues.
- Key Enzymes in NAD Metabolism:
- Discussion on the salvage pathway and two critical enzymes that degrade NAD.
- Importance of regulating NNMT to prevent its deleterious effects, particularly in senescent cells, cancer cells, and fat cells.
- Benefits of 1-MNA
- How 1-MNA can help maintain a balanced NAD metabolism by inhibiting NNMT.
- Potential benefits for conditions like schizophrenia, neurodegeneration, liver diseases, and cancer.
- Research and Studies:
- Overview of studies showing the positive effects of 1-MNA on post-COVID conditions, inflammation, and mitochondrial function.
- Insights from animal studies on 1-MNA's protective effects against metabolic disorders.
- Practical Applications:
- Recommendations for integrating 1-MNA into supplement regimens, especially for those taking NMN or NR.
- Potential benefits for various conditions, including obesity, metabolic syndrome, cardiac disease, liver disease, cancer risk, long COVID, and fatigue.
- Balancing NAD Levels:
- Importance of maintaining NAD levels for energy production, DNA repair, neurotransmitter health, and longevity.
- The role of NAD as a redox molecule and the balance between NAD+ and NADH.
- Conclusion:
- Encouragement to explore further research on NNMT and its impact on health.
- Final thoughts on the potential of 1-MNAas a crucial supplement for maintaining NAD balance and promoting longevity.
References and Links:
- Boulder Longevity Institute: https://boulderlongevity.com/
- SSRP Institute: https://ssrpinstitute.org/
- Studies on NNMT and related conditions: Research
- If you enjoyed this episode, please give it a like, share, and subscribe to the YouTube channel.
- Tune in weekly for more interviews with top doctors and scientists on health optimization and longevity.
If you want to start supplementing with 1-MNA to support your own healthy aging journey, to upregulate your NAD metabolism, support sirtuin genes and prevent the overexpression of the deleterious NNMT Enzyme you can buy it here: 1-MNA and use code NAD to get $25 off your first order
- Stay up-to-date with the latest research and evolve with the science to optimize your health and longevity. See you in the next episode!
Personalised Health Optimisation Consulting with Lisa Tamati
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