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Metagenics Institute Podcast

Metagenics Institute Podcast

Metagenics

Welcome to the Metagenics Institute Podcast where Healthcare Practitioners can hear innovative, cutting-edge information from leading experts from around the world. Join your host, Nathan Rose, to explore the latest evidence in Natural Health, challenge and debunk industry myths and offer practical, tangible, clinical tools which will transform your practice.
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Top 10 Metagenics Institute Podcast Episodes

Goodpods has curated a list of the 10 best Metagenics Institute Podcast episodes, ranked by the number of listens and likes each episode have garnered from our listeners. If you are listening to Metagenics Institute Podcast for the first time, there's no better place to start than with one of these standout episodes. If you are a fan of the show, vote for your favorite Metagenics Institute Podcast episode by adding your comments to the episode page.

Metagenics Institute Podcast - The role of MCAS in the gut, brain and beyond with Tania Dempsey
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01/31/21 • 71 min

As an expert in mast cell activation syndrome (MCAS), Dr Tania Dempsey, imparts priceless information regarding the nature and treatment of this insidious condition. Among many insights, Dr Dempsey explains how to distinguish histamine intolerance from MCAS, the impact of this condition on gastrointestinal health, as well as views on the connection between COVID-19 and MCAS. Importantly, Dr Dempsey draws on years of experience to provide advice on the identification and management of MCAS.

Dr. Dempsey is Board Certified in Internal Medicine and a Diplomate of the American Board of Integrative and Holistic Medicine. She has served as an attending physician at a large multi-specialty medical practice in White Plains, NY, and since opened AIM Centre for Personalised Medicine.

*Highlights *

  • What is MCAS and how prevalent is it? (6:30)
  • Examining the connection between gut health and MCAS (13:00)
  • Histamine intolerance versus MCAS (21:30)
  • Why a personalised diet is important (27:00)
  • MCAS and COVID-19 (38:20)
  • How to spot MCAS (47:20)
  • Stabilising mast cells and avoiding triggers (53:00)

**Useful links and resources:

Follow Metagenics on Instagram here -
https://www.instagram.com/metagenics_anz/

Or on Facebook - https://www.facebook.com/metagenics

Website: https://www.drtaniadempsey.com/
LinkedIn: AIM Centre for Personalised Medicine - https://www.linkedin.com/company/armonk-integrative-medicine#:~:text=Tania%20Tyles%20Dempsey%2C%20MD%2C%20founder,Dr.
Twitter account: https://twitter.com/drtaniadempsey?lang=en

Paper Tania mentions: Afrin LB, Weinstock LB, Molderings GJ. Covid-19 hyperinflammation and post-Covid-19 illness may be rooted in mast cell activation syndrome. Int J Infect Dis. 2020;100:327-332. doi:10.1016/j.ijid.2020.09.016

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529115/

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Metagenics Institute Podcast - The Biological Drivers of Long COVID with Dr Amy Proal
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11/07/22 • 70 min

*The information in this podcast is intended for Healthcare Practitioners.

Long COVID – its highly prevalent, often includes debilitating symptoms and there is currently no consensus on what is driving the syndrome.

Cue Dr Amy Proal. Dr Proal is a microbiologist and CEO of Polybio Research Foundation, and she is driven to elucidate the pathophysiology of long COVID.

In this episode Dr Proal discusses the new science on the biological drivers of long COVID, outlining the evidence for the ‘persistent SARS-CoV-2 reservoir’ hypothesis of long COVID. Further, Dr Proal explains the nefarious mechanisms SARS-CoV-2 has on suppressing immunity, synergising with pathobionts and potentially wreaking havoc on neurological circuits, all of which can help explain long COVID symptomatology such as chronic inflammation, hypercoagulability, sickness behaviour and dysautonomia. The podcast explores spike proteins, co-infections, dysbiosis, vagal nerve dysfunction and more to paint a comprehensive picture of this condition.

To conclude, Nathan and Dr Proal discuss potential therapeutic targets and cast an eye to the future on Dr Proal’s current collaboration with world-leading researchers on long COVID.

Useful Links

Proal AD, VanElzakker MB. Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Contribute to Persistent Symptoms. Front Microbiol. 2021;12:698169. Published 2021 Jun 23. doi:10.3389/fmicb.2021.698169

https://pubmed.ncbi.nlm.nih.gov/34248921/

https://polybio.org/

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Metagenics Institute Podcast - Brain-gut Therapies with GI Psychologist Dr Megan Riehl
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08/15/22 • 46 min

*The information in this podcast is intended for Healthcare Practitioners.

Dr. Megan Riehl is one of only a small number of specialists in the world who practices as a Gastrointestinal Psychologist. She is the Clinical Director of the GI Behavioural Health Program at the University of Michigan, offering comprehensive treatment options for people suffering disorders of gut-brain interaction (DGBI), such as irritable bowel syndrome (IBS). Whilst a great deal of attention in natural medicine is paid to how the gut affects brain function, in this episode, Dr Reihl highlights how the brain can have a profound effect on GI function.

Dr Riehl describes how gastrointestinal (GI) conditions can be better understood and managed by transitioning our framework from a mechanistic model to a biopsychosocial model. She discusses the connection between factors such as early life stress, catastrophising and symptom hypervigilance with the incidence and severity of IBS. Dr Riehl walks listeners through several brain-gut strategies and therapies from self-care to practitioner-guided therapy. Learn about the efficacy of cognitive behvioural therapy (CBT) and gut-directed hypnosis for DGBI and discover several digital tools that practitioners can consider. To finish, the conversation turns to another area Dr Riehl is passionate about – screening and managing disordered eating that is linked to, or can develop from, DGBI. Tune into an episode jammed packed with clinical pearls!

Useful Links

Dr Riehl’s diaphragmatic breathing tutorial - https://www.youtube.com/watch?v=UB3tSaiEbNY

Nerva gut-directed hypnosis app - https://www.mindsethealth.com/hypnotherapy/nerva

ROME Foundation - https://theromefoundation.org/

GI On Demand - https://giondemand.com/

Jagielski CH, Riehl ME. Behavioral Strategies for Irritable Bowel Syndrome: Brain-Gut or Gut-Brain? Gastroenterol Clin North Am. 2021 Sep;50(3):581-593. doi: 10.1016/j.gtc.2021.03.006. Epub 2021 Jun 25. PMID: 34304789. https://pubmed.ncbi.nlm.nih.gov/34304789/

Riehl ME, Scarlata K. Understanding Disordered Eating Risks in Patients with Gastrointestinal Conditions. J Acad Nutr Diet. 2022 Mar;122(3):491-499. doi: 10.1016/j.jand.2021.03.001. Epub 2021 Apr 20. PMID: 33893063. https://pubmed.ncbi.nlm.nih.gov/33893063/

Call out to those who may be interested in participating in an endometriosis study: https://www.nicm.edu.au/research/clinical_trials/endometriosis_study

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Metagenics Institute Podcast - A Functional Approach to Gut Health with Dr Datis Kharrazian
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10/18/21 • 57 min

Datis Kharrazian is a Harvard Medical School trained and award-winning clinical research scientist, academic professor, and world-renowned functional medicine health care provider. He develops evidence-based models to treat autoimmune, neurological, and unidentified chronic diseases with non-pharmaceutical applications. His clinical models of evidence-based medicine are used by several academic institutions and thousands of health care providers throughout the world.

The Kharrazian Institute was developed as an educational institute focused on teaching clinical practice models to healthcare professionals that are interested in nutrition, dietary, and lifestyle approaches to help improve the lives of patients suffering from chronic conditions.

In this episode, Dr. Kharrazian shares his clinical wisdom regarding the management of gastrointestinal health. The conversation ranges from the role of traumatic brain injury in digestive disorders to his approach to assessing and treating gut conditions. This makes for highly valuable content for healthcare professionals, especially those practicing functional medicine.

*Highlights *

  • A functional approach to gut conditions (6:20)
  • Traumatic brain injury and the gut-brain-axis (18:00)
  • Approaching autoimmune digestive disorders (27:00)
  • Correcting gut health from North to South (32:30)
  • Examining intestinal permeability (37:30)
  • The importance of microbiome diversity (44:00)
  • About the Kharrazian Institute (52:00)

Useful links

Dr Datis Kharrazian website: https://drknews.com/

The Kharrazian Institute: https://kharrazianinstitute.com/

Paper - Reaction of Human Monoclonal Antibodies to SARS-CoV-2 Proteins With Tissue Antigens: Implications for Autoimmune Diseases - https://www.frontiersin.org/articles/10.3389/fimmu.2020.617089/full

Other citations for Dr Kharrazian - https://scholar.google.com/citations?user=y2wtigwAAAAJ&hl=en

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Metagenics Institute Podcast - Research Update: PCOS with Professor Elisabet Stener-Victorin
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08/09/21 • 56 min

In this episode, Professor Elisabet Stener-Victorin from Karolinska Institute in Stockholm, shares understandings regarding the aetiology of polycystic ovarian syndrome (PCOS) according to the latest research. As a researcher, Elisabet and her team hope to uncover underlying causes of the disease, with the aim of finding better treatments in future. Interestingly, 20 genetic variations have been identified as well as links between androgen exposure in foetal life and epigenetic changes. Tune in to hear more from Professor Stener-Victorin.

*Highlights *

  • Potential causes of PCOS (3:00)
  • Insights from Elisabet’s research (15:30)
  • How excess androgens in utero impact both genders (23:00)
  • What causes elevated androgen exposure in utero? (30:00)
  • Inflammation – a cause or consequence of PCOS? (37:00)
  • Is the microbiome playing a role in PCOS? (39:30)
  • The influence of electro-acupuncture on PCOS (42:30)
  • Therapeutics on the horizon (52:00)

Useful links and resources

Recent publications

  1. Risal, S., et al. Prenatal androgen exposure and transgenerational susceptibility to polycystic ovary syndrome. Nature medicine 25, 1894-1904 (2019).
  2. Risal S. , et al. Prenatal androgen exposure causes a sexually dimorphic transgenerational increase in offspring susceptibility to anxiety disorders. Transl Psychiatry. 2021 Jan 13;11(1):45. doi: 10.1038/s41398-020-01183-9.PMID: 33441551
  3. Stener-Victorin, E., et al. Animal models to understand the etiology and pathophysiology of polycystic ovary syndrome. Endocr Rev (2020).
  4. Stener-Victorin, E and Deng, Q. Epigenetic inheritance of polycystic ovary syndrome - challenges and opportunities for treatment Nat Rev Endocrinol. 2021 Jul 7. doi: 10.1038/s41574-021-00517-x. Online ahead of print.PMID: 34234312
  5. Stener-Victorin E, Deng Q. Transmission of Polycystic Ovary Syndrome via Epigenetic Inheritance. Trends Mol Med. 2021 Jun 11:S1471-4914(21)00129-5. doi: 10.1016/j.molmed.2021.05.005. Online ahead of print.PMID: 34127396
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Metagenics Institute Podcast - Redefining Adrenal Fatigue with Dr Thomas Guilliams
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04/04/17 • 49 min

Since 1996 Dr Thomas Guilliams has spent his time studying the mechanisms and actions of natural-based therapies, and is an expert in the therapeutic uses of nutritional supplements. He has invested much of his time studying epidemiological data and clinical research to help him develop evidence-based nutritional solutions that enhance the efficacy of nutritional therapies in clinical practice. Dr Guilliams teaches at the University Of Wisconsin School Of Pharmacy, where he holds an appointment as a Clinical Instructor; and at the University Of Minnesota School Of Pharmacy and is a faculty member of the Fellowship in Anti-aging Regenerative and Functional Medicine (A4M). Thomas has spent years looking into the mechanisms of stress and the hypothalamic pituitary adrenal axis (HPA) dysfunction and is the author of several books on the topic of chronic disease prevention. More recently he has authored a useful reference book outlining the effects of stress and the HPA axis, focusing on clinically relevant advances in the understanding of the stress response system.

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Metagenics Institute Podcast - The Science of Longevity with Dr Tommy Wood
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12/01/20 • 90 min

Dr Tommy Wood earned his medical degree at the University of Oxford, and subsequently completed PhD in physiology and neuroscience at the University of Oslo. Currently, he holds academic positions at the University of Washington and Institute for Human and Machine Cognition. One of Dr Wood’s research interests is developing easily-accessible methods with which to track human health, performance, and longevity. In this episode, Dr Wood shares a plethora of information regarding the science of longevity, including patterns in ageing, determining biological age, and importantly, whether specific ingredients can increase longevity.

*Highlights *

  • The fascination with extending the lifespan (5:00)
  • Looking to the Blue Zones (8:30)
  • The biomarkers of ageing (15:50)
  • Determining your biological age (21:00)
  • Biological drivers of ageing (31:40)
  • Diving into caloric restriction (38:00)
  • Macronutrients for health and longevity (55:00)
  • Ingredients to improve longevity (75:00)

Useful links and resources: e.g:
For more Metagenics follow us on Instagram https://www.instagram.com/metagenics_anz/
If you're a Healthcare Practitioner in Australia or New Zealand, join our private Facebook group https://www.facebook.com/groups/MetagenicsAU

Follow Dr Tommy Wood on Instagram here - https://www.instagram.com/drtommywood/
Genetic testing providers Tommy Wood mentions:
Elysium - https://www.elysiumhealth.com/en-us/index
Chronomics - https://www.chronomics.com/dna

Paper – Li J, Bonkowski MS, Moniot S, Zhang D, Hubbard BP, Ling AJ, Rajman LA, Qin B, Lou Z, Gorbunova V, Aravind L, Steegborn C, Sinclair DA. A conserved NAD+ binding pocket that regulates protein-protein interactions during aging. Science. 2017 Mar 24;355(6331):1312-1317. doi: 10.1126/science.aad8242. PMID: 28336669

Link: https://pubmed.ncbi.nlm.nih.gov/28336669/
Paper – Newman S. Supercentenarians and the oldest old are concentrated into regions with no birth certificates and short lifespans. 2019 Jul. doi: 10.1101/704080

Link - https://www.researchgate.net/publication/334497888_Supercentenarians_and_the_oldest-old_are_concentrated_into_regions_with_no_birth_certificates_and_short_lifespans

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Metagenics Institute Podcast - Leaky Gut - Concept or Clinical Entity? A Lesson from Dr Eamonn Quigley
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11/03/20 • 43 min

In this episode, Nathan had the honour of discussing intestinal permeability and ‘leaky gut’ with renowned gastroenterologist, Dr Eamonn Quigley. He is internationally known for his research on gastrointestinal motility disorders, neurogastroenterology and the gut microbiome and has published more than 800 peer-reviewed articles, reviews, editorials, book chapters and case reports. Quigley is past president of the American College of Gastroenterology and the World Gastroenterology Organisation. His current responsibilities include, but are not limited to, the David M. Underwood Chair of Medicine in Digestive Disorders, Head of Gastroenterology and Hepatology at Houston Methodist Hospital, and Professor of Medicine at both the Institute of Academic Medicine and Weill Cornwell Medical College.

*Highlights *

  • Debunking the gut barrier (6:00)
  • Evaluating tests to assess gut permeability (12:40)
  • Does targeting paracellular permeability improve disease? (22:00)
  • The role of the gut microbiome (29:20)
  • Maintaining the gut barrier (33:10)

Useful links and resources: e.g:
Follow Metagenics on Instagram here -
https://www.instagram.com/metagenics_anz/

Or on Facebook - https://www.facebook.com/metagenics

Keep up withthe latest industry news and events by joining our private Practitioner Only Facebook Group - https://www.facebook.com/groups/MetagenicsAU

Article: Quigley EMM, 2016 – ‘Leaky gut - concept or clinical entity?’ - https://pubmed.ncbi.nlm.nih.gov/26760399/
Article: Camilleri M, 2019 – ‘Leaky gut: mechanisms, measurement and clinical implications in humans’ - https://pubmed.ncbi.nlm.nih.gov/31076401/
Article: Zuo L, Kuo WT, Turner JR - Tight Junctions as Targets and Effectors of Mucosal Immune Homeostasis - https://pubmed.ncbi.nlm.nih.gov/32304780/

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*The information in this podcast is intended for Healthcare Practitioners.

What if you could measure and improve your emotional fitness with an inexpensive wearable device and a free app? In this episode, we talk to Dr Paul Zak, a pioneer in the neuroscience of immersion and happiness, who has developed a groundbreaking technology that can do just that.
In this episode, you will learn:

• What is immersion and why is it important for our well-being and performance?

• How does immersion relate to dopamine and oxytocin, two key neurotransmitters that regulate our attention and emotions?

• How can you use Dr Zak’s technology to measure your immersion and psychological safety, and prevent or manage low mood and low energy?

Dr Paul Zak has spent the past two decades searching for signals within the brain to predict what brain’s value and if people will take action. This quest has resulted in discovering neuroscience that uncovered keys to happiness and joy, and more recently, potential clinical benefits in predicting low mood and burnout. In this episode, Paul describes his mapping of what he has dubbed ‘immersion’ – a unique neurological state of engagement that has tremendous predictive power and emerging clinical utility.

Don’t miss this fascinating conversation with Dr Paul Zak, who will share his insights and stories from his decades of research on the brain and happiness. Subscribe to the Metagenics Institute Podcast today and get ready to be immersed in the science of immersion.

Useful links:

Merritt SH, Krouse M, Alogaily RS, Zak PJ. Continuous Neurophysiologic Data Accurately Predict Mood and Energy in the Elderly. Brain Sci. 2022;12(9):1240. Published 2022 Sep 14. doi:10.3390/brainsci12091240

Immersion: The Science of the Extraordinary and the Source of Happiness

• Launch of Tuesday App

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Metagenics Institute Podcast - Psychedelics for Mental Health

Psychedelics for Mental Health

Metagenics Institute Podcast

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04/26/21 • 39 min

In this episode, Nathan sits down with Tania de Jong and Dr Alana Roy from Mind Medicine Australia to discuss the use of psychedelics for mental health. Mind Medicine Australia (MMA) is a charity that seeks to alleviate the suffering caused by mental illness in Australia through expanding the treatment options available to medical practitioners and their patients. MMA are focused on the development of safe and effective psychedelic-assisted therapies to cure a range of mental illnesses.

*Highlights *
Types of psychedelics (6:00)
How psychedelics exert beneficial effects (8:30)
What the research is telling us (12:00)
What a session involves (20:00)
A discussion regarding psychedelic safety (25:50)
Accessibility of psychedelic medicines (31:00)
Mind Medicine Australia initiatives (33:00)
Certificate in Psychedelic-Assisted Therapies (CPAT) (36:00)

*Useful Links and Resources: eg: *

Follow Metagenics on Instagram - @metagenics_anz

https://mindmedicineaustralia.org.au/

For a Certificate in Psychedelic-Assisted Therapies -https://mindmedicineaustralia.org.au/certificate-in-psychedelic-assisted-therapies-cpat/

Link to the International Summit on Psychedelic Therapies - https://mindmedicineaustralia.org.au/international-summit-on-psychedelic-therapies/

Watch this animation to find out why psychedelic-assisted psychotherapy needs to be available to those who are suffering - https://www.youtube.com/watch?v=VSO8UTQvYUw

Link to news in this space - https://mindmedicineaustralia.org/news/

Psychiatrist Dr Paul Fitzgerald’s recent short article on the urgent need for innovation in this space - https://medium.com/@pbfitzgerald/the-challenges-of-depression-treatment-in-2020-abd74269764

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FAQ

How many episodes does Metagenics Institute Podcast have?

Metagenics Institute Podcast currently has 104 episodes available.

What topics does Metagenics Institute Podcast cover?

The podcast is about Health & Fitness, Alternative Health, Natural Health, Healthy Living, Podcasts and Science.

What is the most popular episode on Metagenics Institute Podcast?

The episode title 'How Immersion Can Improve Your Mood, Energy and Performance with Dr Paul J. Zak' is the most popular.

What is the average episode length on Metagenics Institute Podcast?

The average episode length on Metagenics Institute Podcast is 57 minutes.

How often are episodes of Metagenics Institute Podcast released?

Episodes of Metagenics Institute Podcast are typically released every 21 days.

When was the first episode of Metagenics Institute Podcast?

The first episode of Metagenics Institute Podcast was released on Nov 18, 2016.

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