The role of MCAS in the gut, brain and beyond with Tania Dempsey

01/31/21 • 71 min

As an expert in mast cell activation syndrome (MCAS), Dr Tania Dempsey, imparts priceless information regarding the nature and treatment of this insidious condition. Among many insights, Dr Dempsey explains how to distinguish histamine intolerance from MCAS, the impact of this condition on gastrointestinal health, as well as views on the connection between COVID-19 and MCAS. Importantly, Dr Dempsey draws on years of experience to provide advice on the identification and management of MCAS.

Dr. Dempsey is Board Certified in Internal Medicine and a Diplomate of the American Board of Integrative and Holistic Medicine. She has served as an attending physician at a large multi-specialty medical practice in White Plains, NY, and since opened AIM Centre for Personalised Medicine.

*Highlights *

What is MCAS and how prevalent is it? (6:30)
Examining the connection between gut health and MCAS (13:00)
Histamine intolerance versus MCAS (21:30)
Why a personalised diet is important (27:00)
MCAS and COVID-19 (38:20)
How to spot MCAS (47:20)
Stabilising mast cells and avoiding triggers (53:00)

**Useful links and resources:

Follow Metagenics on Instagram here -
https://www.instagram.com/metagenics_anz/

Or on Facebook - https://www.facebook.com/metagenics

Website: https://www.drtaniadempsey.com/
LinkedIn: AIM Centre for Personalised Medicine - https://www.linkedin.com/company/armonk-integrative-medicine#:~:text=Tania%20Tyles%20Dempsey%2C%20MD%2C%20founder,Dr.
Twitter account: https://twitter.com/drtaniadempsey?lang=en

Paper Tania mentions: Afrin LB, Weinstock LB, Molderings GJ. Covid-19 hyperinflammation and post-Covid-19 illness may be rooted in mast cell activation syndrome. Int J Infect Dis. 2020;100:327-332. doi:10.1016/j.ijid.2020.09.016

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529115/

*Highlights *

What is MCAS and how prevalent is it? (6:30)
Examining the connection between gut health and MCAS (13:00)
Histamine intolerance versus MCAS (21:30)
Why a personalised diet is important (27:00)
MCAS and COVID-19 (38:20)
How to spot MCAS (47:20)
Stabilising mast cells and avoiding triggers (53:00)

**Useful links and resources:

Follow Metagenics on Instagram here -
https://www.instagram.com/metagenics_anz/

Or on Facebook - https://www.facebook.com/metagenics

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529115/

Previous Episode

The Science Behind Medicinal Cannabis with Jason Wilson

Science educator, Jason Wilson is the host of The Curious About Cannabis Podcast which answers questions about the world’s most controversial plant – Cannabis. In this episode, Wilson provides an in-depth history lesson on Cannabinoid science, as well as the use of Cannabis extracts for medicinal purposes and the future of Cannabis research.

Highlights:

Jason’s journey to Cannabinoid research (1:30)
A history lesson on Cannabinoid science (14:00)
Examining endocannabinoid derangement and supplementation with phytocannabinoids (36:00)
The entourage effect (45:00)
Lesser known and emerging cannabinoids (55:00)
Medicinal cannabis (1:02:00)
Directions for future research (1:14:00)

Useful links and resources:

Follow Metagenics on Instagram here -
https://www.instagram.com/metagenics_anz/

Or on Facebook - https://www.facebook.com/metagenics

If you are a Healthcare Practitioner in Australia or New Zealand, keep up latest industry news and events by joining our private Practitioner Only Facebook Group - https://www.facebook.com/groups/MetagenicsAU

Jason Wilson’s book – Curious About Cannabis: A Scientific Introduction to the World's Most Controversial Plant - https://www.cacpodcast.com/book.html#/

Next Episode

Reversing Your Epigenetic Age with Kara Fitzgerald

Kara Fitzgerald and her research team were the first to demonstrate potential reversal of biological age in humans by targeting methylation. In their study, the prescribed program included multiple components with documented mechanistic activity on epigenetic pathways. Tune in to hear the details of her research and learn how to influence your epigenetics.
Dr. Kara Fitzgerald has a doctorate of naturopathic medicine, and has been published in numerous peer-reviewed journals. She is on faculty at the Institute for Functional Medicine, and is an Institute for Functional Medicine Certified Practitioner. She regularly lectures internationally for several organizations and is in private practice in Sandy Hook, Connecticut.

Highlights
What motivated Kara to move into epigenetic research? (2:30)
Introduction to epigenetic clocks (9:00)
What positively impacts our epigenetics? (24:00)
Kara details her research (30:00)
Methylation adaptogens (35:00)
Kara’s hopes for future research (45:00)

*Useful Links and Resources *
https://www.drkarafitzgerald.com/

For Kara’s list of methylation adaptogens and links to her books: https://www.drkarafitzgerald.com/professionals/methylation-diet-lifestyle/

Kara’s research - https://www.researchgate.net/publication/342929824_Reversal_of_Epigenetic_Age_with_Diet_and_Lifestyle_in_a_Pilot_Randomized_Clinical_Trial

Research links: https://www.drkarafitzgerald.com/professionals/research-news-ideas/

My DNA age - https://www.mydnage.com/

HK Epitherapeutics - http://www.hkgepitherapeutics.com/

About Moshe Szyf - http://www.hkgepitherapeutics.com/about/moshe-szyf/

Metagenics Congress - https://metagenicsinstitute.com.au/congress-2021