Health Via Modern Nutrition with Dr. Latt Mansor - New Study Claims Ketones INCREASE Inflammation - Why the Results Are Misleading || Research Roundup

New Study Claims Ketones INCREASE Inflammation - Why the Results Are Misleading || Research Roundup

04/15/19 • 8 min

Health Via Modern Nutrition with Dr. Latt Mansor

Wait...hasn't ketones been shown to reduce inflammation in prior studies?

When a new study researched the effects ketones have on inflammation, the results were opposite to what everyone expected...including the researchers themselves.

The paper was published in the Journal of Molecular Nutrition and Food Research, and the research group that carried out the work were led by Dr Jonathan Little at the University of British Columbia.

Rather than inhibiting the inflammatory response through BHB’s (a ketone body) actions on the NLRP3 inflammasome, the researchers found that activity of several immune markers was higher when people had consumed ketones.

It can be easy to jump to conclusions and state that "Exogenous Ketones = Increased Inflammation"...as the title of the paper acutely suggests.

Dr. Brianna Stubbs tackles this study and provides further, necessary nuance on how the experiment was conducted, why the results may actually be more positive than negative, and why this development warrants future research.

Referenced Studies:
1. https://onlinelibrary.wiley.com/doi/full/10.1002/mnfr.201801171
2. https://www.ncbi.nlm.nih.gov/pubmed/30239561

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Wait...hasn't ketones been shown to reduce inflammation in prior studies?

When a new study researched the effects ketones have on inflammation, the results were opposite to what everyone expected...including the researchers themselves.

The paper was published in the Journal of Molecular Nutrition and Food Research, and the research group that carried out the work were led by Dr Jonathan Little at the University of British Columbia.

It can be easy to jump to conclusions and state that "Exogenous Ketones = Increased Inflammation"...as the title of the paper acutely suggests.

Referenced Studies:
1. https://onlinelibrary.wiley.com/doi/full/10.1002/mnfr.201801171
2. https://www.ncbi.nlm.nih.gov/pubmed/30239561

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SAVE 50% OFF GO CUBES: https://www.hvmn.com/pod

(offer ends April 19th, 2019)

Take a short survey that will help us improve the podcast and be entered in a HVMN Ketone giveaway: https://go.hvmn.com/podcastsurvey

Previous Episode

Metabolic Syndrome: Criteria, Causes, & How to REVERSE IT || #108 ft. Ivor Cummins

Metabolic syndrome. It’s a term we throw out all the time on this podcast. It’s about time we have an episode to specifically define metabolic syndrome, why we should care, and what we can do about it.

To help do this, we have none other than Ivor Cummins, aka The Fat Emperor, on the podcast today. Cut from a similar cloth as folks like Dave Feldman and host Geoffrey Woo, Ivor comes from a professional background in engineering, therefore applying an engineers mindset and problem solving to the field of nutrition and metabolic health.

After spending 30 years in corporate technical leadership positions, Ivor is now the Chief Program Officer for Irish Heart Disease Awareness (IHDA). Ivor regularly speaks at well-known health and medical conferences around the world on the same stage as professors and doctors.

In this episode, you'll discover:

1. What the criteria is for diagnosing metabolic syndrome, what the root causes are, and how to reverse it through lifestyle changes.

2. What a CAC (Coronary artery calcium) scan is and how calcium is a good direct marker for cardiovascular disease

3. The nuances of different types of fats (saturated, unsaturated, polyunsaturated, and trans fats).

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Next Episode

mTor Signaling & Cell Growth: Targeting via Ketogenic Diet & Intermittent Fasting || #109 ft. Dr. Keith Baar

mTor...mechanistic target of rapamycin. What is it?

We reference mTor frequently on our podcast, particularly when we discuss fasting or keto and their potential for extending health & lifespan.

mTor is a pathway that helps controls cell growth. In the most simplest terms: When you have high mTor activation, you promote growth in the body. When you have low mTor activation, you promote repair and maintenance.

mTor is sensitive to the nutrients we consume (especially protein and carbohydrate), so by controlling our diet, we can control mTor. This is an exciting area because a lot of people think mTor plays a role for longevity & metabolism. The ketogenic diet and intermittent fasting are natural ways to target & regulate your mTor.

Dr. Keith Baar, a professor of Physiology at the UC Davis Medical School, is an expert on mTor and muscle growth. This is a valuable conversation for anyone interested in mTor and strategies to control it, and why non-tissue specific approaches like rapamycin might have problems.

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(offer ends April 19th, 2019)

Take a short survey that will help us improve the podcast and be entered in a HVMN Ketone giveaway: https://go.hvmn.com/podcastsurvey