Health Hackd Podcast

Technology addiction has escalated over the past several years, as cell phones and apps have become more versatile, but it's become especially apparent during 2020. And like most addictions, our tech addiction is not without consequences. While we are more digitally connected than we've ever been, we are lonelier than ever. Deleterious tech usage has made us emotionally, physically, and relationally sick.
But there is a cure to the loneliness that technology often brings: human relationships. Personal relationships (not "likes" on social media) are just as vital to our personal health as diet and exercise.
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Resources:

• Tech usage statistics
• The Social Dilemma documentary
• Irresistible: The Rise of Addictive Technology and the Business of Keeping Us Hooked by Adam Alter
• Loneliness and health: potential mechanisms
• Social support and health: a review of physiological processes potentially underlying links to disease outcomes
• Social Relationships and Mortality Risk: A Meta-analytic Review
• Social relationships, sleep quality, and interleukin-6 in aging women

Disclaimer: This podcast is not intended to provide medical advice, diagnosis or treatment. The products, information, services and other content provided on and through this podcast, including information that may be provided in the show notes (directly or via linking to third-party sites), are provided for informational purposes only. Please consult with your physician or other healthcare professional regarding any medical or health-related diagnosis or treatment options.

"Winter is coming, we know what's coming with it."
In addition to the seasonal flu this winter, we are faced with another threat to our health that attempts to compromise our immune system. Fortunately, research has shown a multitude of ways we can strengthen our immunity and reduce the severity infections, bacteria, and viruses.
Evidence surrounding the role of Vitamin D in immune health continues to mount. Today, we can a look at what makes this vitamin so special, and why it's particularly important during the winter months. In anticipation of this, we can begin strengthening our body's natural defense system today, so when we face these threats, we are ready.
So prepare yourselves, because winter is coming...
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Resources:

• Vitamin D Metabolism Flowchart
• Vitamin D supplementation could possibly improve clinical outcomes of patients infected with Coronavirus-2019 (COVID- 2019)
• Vitamin D insufficiency is prevalent in severe COVID-19
• Patterns of COVID-19 Mortality and Vitamin D: An Indonesian Study
• Vitamin D deficiency and insufficiency among US adults: prevalence, predictors and clinical implications
• Vitamin D Toxicity in Adults: A Case Series from an Area with Endemic Hypovitaminosis D
• Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren
• Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data
• The vitamin D–antimicrobial peptide pathway and its role in protection against infection
• Effect of calcifediol treatment and best available therapy versus best available therapy on intensive care unit admission and mortality among patients hospitalized for COVID-19: A pilot randomized clinical study
• Meal conditions affect the absorption of supplemental vitamin D3
• Dietary fat increases vitamin D-3 absorption

Disclaimer: This podcast is not intended to provide medical advice, diagnosis or treatment. The products, information, services and other content provided on and through this podcast, including information that may be provided in the show notes (directly or via linking to third-party sites), are provided for informational purposes only. Please consult with your physician or other healthcare professional regarding any medical or h

Do you use a deodorant or antiperspirant? Do you know what ingredients make up that magical deodorizer that you put under your arm every day?
Similar to nutrition, where it's important to understand what you're putting IN your body, when it comes to body care products, it's very important to understand what you're putting ON your body. The skin is very absorbent, so carefully discerning which products you use daily can be a contributing factor to your overall health & wellness.
In this episode, we take a look at the 5 most common ingredients that appear in underarm care products, what harm those chemicals could bring, and some natural alternatives to the artificial deodorants and antiperspirants.

• Schmidt's
• Tom's
• Native
• Lume
• Routine
• Little Seed Farm
• Crystal

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Resources:

• Aluminium, antiperspirants and breast cancer
• Antiperspirant Use and the Risk of Breast Cancer
• An earlier age of breast cancer diagnosis related to more frequent use of antiperspirants/deodorants and underarm shaving
• Aluminium chloride promotes anchorage-independent growth in human mammary epithelial cells
• Hyperaluminemia in a Woman Using an Aluminum-Containing Antiperspirant for 4 Years
• In vitro study of absorption of aluminum from antiperspirants through human skin
• Use of Underarm Cosmetic Products in Relation to Risk of Breast Cancer
• American Cancer Society on Antiperspirants
• Aluminum and Alzheimer's disease: after a century of controversy, is there a plausible link?
• Parabens can enable hallmarks and characteristics of cancer in human breast epithelial cells
• Urinary concentrations of environmental phenols and their associations with breast cancer incidence
• Urinary Paraben Concentrations and Ovarian Aging among Women from a Fertility Center
• Triclosan and antimicrobial resistance in bacteria: an overview

Disclaimer: This podcast is not intended to provide medical advice, diagnosis or treatment. The products, information, services and other content provided on and through this podcast, including information that may be provided in the show notes (directly or via linking to third-party sites), are provided for informational purposes only. Please consult with your physician or other healthcare professional regarding any medical or health-related diagnosis or treatment options.

We finally dig into one of our highest requested topics...fasting. Although the concept of fasting has been around for centuries, it continues to gain in popularity due to the profound benefits it exhibits on yeast, rodents, monkeys, and more recently, humans. There is a wide variety of fasting techniques: intermittent fasting, time-restricted eating, alternate-day fasting, 5:2 fasting, extended water-only fasting, etc. This week, Andy and Aaron break down:

• The various types of fasting methods
• The health benefits of fasting
• The current research on fasting
• Our personal experience with fasting
• Best practices and warnings for implementing your own fasting routine

Resources:

• Early Time‐Restricted Feeding Reduces Appetite and Increases Fat Oxidation
• Time-restricted feeding (16/8) in resistance-trained males
• Fasting: Molecular Mechanisms and Clinical Applications
• Calorie Restriction and Fasting Diets: What Do We Know?
• The effects of intermittent fasting: a randomized trial in young overweight women
• Alternate day fasting (ADF)
• Flipping the Metabolic Switch
• Intermittent fasting: a systematic review and meta-analysis of RCTs
• Effects of A One-week Fasting Therapy
• Fasting and growth hormone secretion
• (GH) secretory burst frequency during a two-day fast in normal men
• Randomized cross-over trial of short-term water-only fasting
• Autophagy: cellular and molecular mechanisms
• Short-term fasting induces profound neuronal autophagy
• mTOR as a central regulator of lifespan and aging
• Caloric restriction improves health and survival of rhesus monkeys
• Calorie restriction in biosphere 2
• CALERIE Biobank Analysis
• Calorie restriction and aging
• Fasting and Markers of the Circadian Clock, Aging, and Autophagy in Humans
• Fasting: Molecular Mechanisms and Clinical Applications
• Zero fasting app
• Life fasting app

Disclaimer: This podcast is not intended to provide medical advice, diagnosis or treatment. Please consult with your physician or other healthcare professional regarding any medical or health-related diagnosis or treatment options.

The "Gluten-Free" movement for those without Celiac Disease was one of the earliest health trends in recent years and remains a very popular dietary option today. Nearly every grocery store, restaurant, and recipe has gluten-free options. While a medical necessity for those with Celiac Disease, others voluntarily choose to maintain a gluten-free diet. There has been heavy debate on whether or not there is a health benefit to following a gluten-free diet if you don't have Celiac Disease, which has led to the emergence of the term "Non-Celiac Gluten (Wheat) Sensitivity". Since headlines and anecdotes muddy the waters on this issue, Andy and Aaron dive into the research to get some answers, as well as share their experience with gluten.
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Resources:

• Jimmy Kimmel - What is Gluten?
• Non-Celiac Gluten Sensitivity: The New Frontier of Gluten Related Disorders [Nutrients 2013]
• Non-Celiac Wheat Sensitivity: Exploring a New Clinical Entity [American Journal of Gastroenterology 2012]
• Effect of Gliadin on Intestinal Permeability [Nutrients 2015]
• Markers of Non-Celiac Wheat Sensitivity in Patients with Chronic Fatigue Syndrome [Gut 2019]
• Intestinal Cell Damage in Individuals Reporting Sensitivity to Wheat in the Absence of Celiac Disease [Gut 2016]
• Serological Tests in Gluten Sensitivity (Nonceliac Gluten Intolerance) [Journal of Clinical Gastroenterology 2012]
• Neurologic and Psychiatric Manifestations of Celiac Disease and Gluten Sensitivity [Psychiatric Quarterly 2012]
• Headache Associated with Celiac Disease: A Systematic Review and Meta-Analysis [Nutrients 2018]
• A survey on patients suspected of having non-celiac gluten sensitivity [BMC Medicine 2014]
• Migraine and Celiac Disease [Journal of Head and Face Pain 2003]
• Extra-intestinal manifestations of non-celiac gluten sensitivity: An expanding paradigm [World Journal of Gastroenterology 2018]
• Anxiety but Not Depression Decreases in Coeliac Patients After One-Year Gluten-Free Diet [Scandinavian Journal of Gastroenterology 2001]
• Dietary Gluten and the Development of Type 1 Diabetes [Diabetologia 2014]
• Gluten Sensitivity: From Gut to Brain [The Lancet Neurology 2010]
• Increased Prevalence and Mortality in Undiagnosed Celiac Disease [Gastroenterology 2009]
• Cyrex Laboratories: Array 3