
Episode 36: Estrogen Dominance Explained: The Link to Painful Periods and Mood Swings with Dr. Michelle Weeks
02/17/25 • 79 min
Are you experiencing painful periods, mood swings, or unexplained weight gain? If so, you might be dealing with estrogen dominance. (Previously episode 7 of season 2)
In this insightful episode of TMI Talk, Dr. Mary Grimberg welcomes Dr. Michelle Weeks to dive deep into this often-overlooked condition that affects so many women.
Key highlights from the episode include a breakdown of what estrogen dominance is and its impact on the body, discussing the important roles of progesterone and estrogen throughout the menstrual cycle, and why the balance (or imbalance) of these hormones can lead to a variety of symptoms. The discussion also covers the perils of chronic stress, a common contributor to hormonal imbalance due to its effect on cortisol levels, and its downstream impact on conditions such as insulin resistance.
Listeners will gain a better understanding of the symptoms of estrogen dominance, including abnormal menstrual bleeding, fibro-cystic breasts, endometriosis, and more. Dr. Weeks also provides practical guidance on hormone testing, lifestyle changes, and dietary adjustments to manage estrogen levels effectively.
Takeaways and actionable steps:
- Consider getting your hormone levels tested on specific days of your menstrual cycle (Day 3 for estrogen, Day 18-21 for progesterone) for accurate assessment.
- Explore the Dutch Test if you have irregular periods or are on birth control.
- Start managing stress effectively through mindfulness practices like meditation, which can lead to balanced cortisol levels.
- Begin supporting your liver with cruciferous vegetables, fiber-rich foods, and probiotics for better estrogen detoxification.
- Engage in regular strength training and post-meal walks to aid insulin sensitivity and metabolic health.
- Evaluate the products you use daily and consider replacing those with harmful endocrine disruptors with cleaner options.
For further insight, revisit Episode 2 of Season 2 on anxiety and stress management to complement the knowledge gained in this episode.
Listeners can also take a free hormone symptom quiz available on Dr. Michelle Weeks' Instagram (@weekswellness) bio to gain more clarity on potential hormonal imbalances.
Connect with Dr. Michelle Weeks
- Website → WeeksWellness.com
- Instagram - @WeeksWellness
Timestamped Overview
00:00 Progesterone-Estrogen Ratio & Stress
10:08 Understanding Hormonal Balance in Women
15:21 Using DUTCH Test for Hormone Analysis
20:15 Hormonal Cycle and Ovulation Process
24:14 Signs of Estrogen Dominance
27:54 Menstrual Product Capacity Comparison
37:20 Signs of Estrogen Imbalance
41:51 Progesterone and Cortisol Pathways Explained
44:35 Stress, Cortisol, and Fertility Connection
51:32 Insulin Resistance and Metabolic Dysfunction
58:44 Stress's Impact on Progesterone Levels
01:01:14 Progesterone Cream and Estrogen Detox
01:05:25 Pair Carbs, Walk After Meals
01:14:32 Authenticity and Inner Healing Journey
01:18:01 "Discover Dr. Mary's Integrative Practice"
Workshop:
The “Woo Woo” Explained: How Energetics, Fascia, Lymph, and the Nervous System Impact Movement for Rehab Professionals
Dont worry, it will be recorded and sent to you if you can't make it live.
📅 May 6th, 2025
⏰ 6PM CST/ 4PM PST / 7PM EST
📍On zoom (will be recorded)
You can learn more and sign up here. I hope you can join us!
If you are a health or movement professional and want to stay in touch with future episodes, webinars, courses, events and more. Subscribe to my email list below:
drmarygrimberg.com
I’ll see you in a week!
Are you experiencing painful periods, mood swings, or unexplained weight gain? If so, you might be dealing with estrogen dominance. (Previously episode 7 of season 2)
In this insightful episode of TMI Talk, Dr. Mary Grimberg welcomes Dr. Michelle Weeks to dive deep into this often-overlooked condition that affects so many women.
Key highlights from the episode include a breakdown of what estrogen dominance is and its impact on the body, discussing the important roles of progesterone and estrogen throughout the menstrual cycle, and why the balance (or imbalance) of these hormones can lead to a variety of symptoms. The discussion also covers the perils of chronic stress, a common contributor to hormonal imbalance due to its effect on cortisol levels, and its downstream impact on conditions such as insulin resistance.
Listeners will gain a better understanding of the symptoms of estrogen dominance, including abnormal menstrual bleeding, fibro-cystic breasts, endometriosis, and more. Dr. Weeks also provides practical guidance on hormone testing, lifestyle changes, and dietary adjustments to manage estrogen levels effectively.
Takeaways and actionable steps:
- Consider getting your hormone levels tested on specific days of your menstrual cycle (Day 3 for estrogen, Day 18-21 for progesterone) for accurate assessment.
- Explore the Dutch Test if you have irregular periods or are on birth control.
- Start managing stress effectively through mindfulness practices like meditation, which can lead to balanced cortisol levels.
- Begin supporting your liver with cruciferous vegetables, fiber-rich foods, and probiotics for better estrogen detoxification.
- Engage in regular strength training and post-meal walks to aid insulin sensitivity and metabolic health.
- Evaluate the products you use daily and consider replacing those with harmful endocrine disruptors with cleaner options.
For further insight, revisit Episode 2 of Season 2 on anxiety and stress management to complement the knowledge gained in this episode.
Listeners can also take a free hormone symptom quiz available on Dr. Michelle Weeks' Instagram (@weekswellness) bio to gain more clarity on potential hormonal imbalances.
Connect with Dr. Michelle Weeks
- Website → WeeksWellness.com
- Instagram - @WeeksWellness
Timestamped Overview
00:00 Progesterone-Estrogen Ratio & Stress
10:08 Understanding Hormonal Balance in Women
15:21 Using DUTCH Test for Hormone Analysis
20:15 Hormonal Cycle and Ovulation Process
24:14 Signs of Estrogen Dominance
27:54 Menstrual Product Capacity Comparison
37:20 Signs of Estrogen Imbalance
41:51 Progesterone and Cortisol Pathways Explained
44:35 Stress, Cortisol, and Fertility Connection
51:32 Insulin Resistance and Metabolic Dysfunction
58:44 Stress's Impact on Progesterone Levels
01:01:14 Progesterone Cream and Estrogen Detox
01:05:25 Pair Carbs, Walk After Meals
01:14:32 Authenticity and Inner Healing Journey
01:18:01 "Discover Dr. Mary's Integrative Practice"
Workshop:
The “Woo Woo” Explained: How Energetics, Fascia, Lymph, and the Nervous System Impact Movement for Rehab Professionals
Dont worry, it will be recorded and sent to you if you can't make it live.
📅 May 6th, 2025
⏰ 6PM CST/ 4PM PST / 7PM EST
📍On zoom (will be recorded)
You can learn more and sign up here. I hope you can join us!
If you are a health or movement professional and want to stay in touch with future episodes, webinars, courses, events and more. Subscribe to my email list below:
drmarygrimberg.com
I’ll see you in a week!
Previous Episode

Episode 35: The Silent Epidemic: Burnout in a Profession Meant to Heal w Dr. Meredith Grossman
Are you feeling overwhelmed and exhausted from your job? (Previously episode 6 of season 2)
Dr. Mary Grimberg delves into the pervasive issue of workplace burnout, especially in the healthcare sector, with guest expert Dr. Meredith Grossman, a practicing physical therapist and the founder of Health Care Unraveled.
Dr. Mary and Dr. Meredith explore the often-taboo topic of workplace burnout and its extensive impacts on physical and mental health. Dr. Meredith shares her personal journey through burnout and how it inspired her to create a platform dedicated to helping healthcare professionals overcome this challenge.
Key highlights from the episode include:
- Understanding how burnout affects your body and mental health across various industries.
- The normalizing of toxic work environments and the importance of recognizing burnout symptoms such as anxiety, irritability, and physical health issues like insomnia and cardiovascular problems.
- The crucial role of relational health and social support, and its impact on overall well-being.
- Practical tips on setting boundaries and finding ways to protect your energy in both toxic and demanding work environments.
- The concept of the growth edge and how small, sustainable steps can alleviate the pressure of burnout.
For those interested in learning more, Meredith offers programs and webinars that specifically target burnout in the healthcare sector. Follow her on Instagram (@MeredithGrossmanPT) and visit her website (healthcareunraveled.com) for more resources.
Timestamped Overview
00:00 Exploring Burnout Across Industries
03:32 "Toxicity in Healthcare Norms"
06:54 Normalization of Overwork and Sacrifice
12:02 Rethinking Exhaustive Work Routines
14:52 Burnout's Impact on Relationships
17:37 Hidden Health: Beyond Physical Fitness
23:39 Start Small: Set Work Boundaries
26:39 People Pleasers and Perfectionists' Struggles
31:46 Healthcare Burnout and Self-Care Priorities
35:13 Holistic Approach to Combat Burnout
37:07 Overcoming People Pleasing
42:37 Balancing Authenticity and Professionalism
46:27 "You Are Not the Problem"
48:51 Burnout Workshops & Webinars
Workshop:
The “Woo Woo” Explained: How Energetics, Fascia, Lymph, and the Nervous System Impact Movement for Rehab Professionals
Dont worry, it will be recorded and sent to you if you can't make it live.
📅 May 6th, 2025
⏰ 6PM CST/ 4PM PST / 7PM EST
📍On zoom (will be recorded)
You can learn more and sign up here. I hope you can join us!
If you are a health or movement professional and want to stay in touch with future episodes, webinars, courses, events and more. Subscribe to my email list below:
drmarygrimberg.com
I’ll see you in a week!
Next Episode

Episode 37: Making Friends in a Fast-Paced World: How to Build Community
Are you struggling to find community and make meaningful connections in today's fast-paced world? (Previously episode 8 of season 2)
Dive into this episode as she delves into the art of building community and friendships. Dr. Mary sheds light on the challenges of social anxiety, especially in a post-COVID landscape, and shares her personal journey of overcoming these barriers.
Key highlights include tips on finding like-minded individuals through hobbies like tennis or stand-up comedy, managing social anxiety through gradual exposure, and the importance of nurturing new friendships with genuine interest and connection. Dr. Mary emphasizes the notion of "zero battery friends" – those with whom you can truly be yourself and feel recharged.
Listeners are encouraged to put these lessons into action by identifying personal growth edges and starting small. Whether it's joining a beginner class or simply saying hi to neighbors, Dr. Mary offers practical advice for pushing past comfort zones. Additionally, you can strengthen new relationships by showing genuine interest in others and initiating follow-up interactions, whether in person or through social media.
For follow-up, Dr. Mary references resources like Chris Voss's work and the classic book "How to Win Friends and Influence People" to enhance social skills and build rapport. Embark on your journey to forming a supportive and enriching community by tuning in and taking the first steps towards connection.
Don't forget to subscribe and connect with Dr. Mary on social media for more insights and support on building a resilient community.
TIMESTAMPED OVERVIEW
00:00 Reconnecting and Building Community
06:00 Overcoming Anxiety Through Gradual Exposure
06:45 Managing Social Anxiety: Introductory Settings
12:00 "Overcoming Social Anxiety Steps"
14:30 "Engage by Listening and Asking"
18:35 Mastering Social Skills
22:02 Finding Your Social Connections
25:47 Authentic Connection Without Manipulation
27:00 Reintegrating Into Community After Trauma
30:06 Pushing Comfort for Growth
Workshop:
The “Woo Woo” Explained: How Energetics, Fascia, Lymph, and the Nervous System Impact Movement for Rehab Professionals
Dont worry, it will be recorded and sent to you if you can't make it live.
📅 May 6th, 2025
⏰ 6PM CST/ 4PM PST / 7PM EST
📍On zoom (will be recorded)
You can learn more and sign up here. I hope you can join us!
If you are a health or movement professional and want to stay in touch with future episodes, webinars, courses, events and more. Subscribe to my email list below:
drmarygrimberg.com
I’ll see you in a week!
TMI Talk with Dr. Mary - Episode 36: Estrogen Dominance Explained: The Link to Painful Periods and Mood Swings with Dr. Michelle Weeks
Transcript
Hello, everyone. I wanted to do a prelude to or prelude, I don't know if I'm saying that right, to this episode of estrogen dominance. And,
basically, I wanna do this because there's a lot of talk about hormones and how things break down, and I do the best that I can to summarize things in order for it to be more digestible. But I thought explaining it a little bit more here would help prepare you for the episode so you can start to und
If you like this episode you’ll love
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