The Hotflash inc podcast

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This week Ann Marie talks all about the biggest news to hit menopause since... since... there hasn't been news this big, ever; how a simple memory test ruined my day, and an HRT story you don't hear every day.

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Dr Angela DeRosa is a doctor of osteopathy, integrative physician and hormone specialist in Arizona. She has a unique take on the current peri/menopause landscape as a doctor of osteopathy who also worked as senior medical director for Procter & Gamble, helping them launch osteoporosis treatments and try – and fail – to get a testosterone patch for women approved for use in 2004.
During her years with the pharmaceutical division, she saw firsthand how women’s ability to get proper medical care and treatment is thwarted due to politics, gender bias and poorly trained physicians. Her mission is to teach women about what’s happening to them physically, how they can obtain proper treatment, and how to change the paradigm of medicine so women everywhere can live healthier and happier lives.
Dr DeRosa discusses her view and experience of testosterone, which she says few doctors understand. This includes her endorsement of and cautions about the controversial use of pellets, as well as the important role of the thyroid, the vital interplay with blood sugar and the road to insulin resistance, and much more.

Highlights:

• What it’s like working for Big Pharma
• Her view on Intrinsa, the Proctor & Gamble testosterone patch the FDA did not approve almost 20 years ago
• We are more than estrogen – and why testosterone is pivotal
• The vital interplay between falling testosterone and insulin resistance
• The crucial thyroid piece – and why thyroid health must come first
• Why so many people don’t understand how to properly administer testosterone
• Why pellets are like colour TV (and what people get wrong about them
• How to avoid unsafe doses
• What is "fulminant fear", why it's rare and how to avoid it
• Her take on “menopause is natural”
• Her take on fezolinetant, aka Veozah, the non-hormonal drug for hot flashes
• Why you want your hormone therapy to be “biomemetic” aka bioidentical
• What you think you know about compounding pharmacies is wrong (including that they are always “expensive”)
• Why we need to look at the “whole universe” of what’s available

Where to find Dr DeRosa:

• drhotflash.com
• hormonalhealthinstitute.com

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Day raver, cold swimmer, rabble-rouser, educator, author, podcaster, academic and publisher of scientific papers: Joyce Harper is a professor of reproductive science at the Institute for Women's Health, University College London.

She’s also author of the 2021 book Your Fertile Years and hosts the podcast Why didn’t anyone tell me this?

Harper is uncompromised and unflappable. She is all about the evidence. She’s not opposed to HRT but isn’t a breathless enthusiast either. It has to be about the evidence, she argues, otherwise it’s just stories and anecdotes that don’t add up to anything.

NB: We are both members of a balanced-approach group called MenoClarity, and we recorded this podcast before Joyce was quoted in a controversial Daily Mail article alleging excessive and unsafe HRT prescribing practices at a chain of private clinics in the UK.

When I followed up with her about it, she said: "We need to give women accurate information about the menopause and treatments. In the UK we've created huge negativity – some suggesting menopause is a disorder. It's not fair to women and I really worry for the next generations who are now nearing menopause. Menopause can be difficult for some. But for most it's a transition and life post menopause can be the most exciting and liberating stage of our lives."
(As always, I’m not a medical professional and this podcast is not medical advice. Expert opinion varies widely. Please listen to the disclaimer at the end podcast as well.)

Highlights:

• Almost 30 years after she completed her PhD, women still don’t understand their bodies
• Why we need to teach people what’s “normal” so they know when to seek help
• How she approaches research – and how we need to as well
• Her top myths in women’s health and menopause
• When you should go on HRT and why dosing matters
• How overall health sets you up for perimenopause
• Issues with the push for testosterone
• Why anecdotes are not research
• Her research-based conclusions the claims that can prevent dementia
• Why being post-menopause is so great
• Her homework assignment for every perimenopausal woman

Where to find Joyce:

Web: Joyceharper.com; Globalwomenconnected.com
Twitter: @profjoyceharper
Instagram @profjoyceharper

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Gerianne DiPiano is chairman and CEO of FemmePharma, which produces among other things a range of solutions for women going through menopause. That includes personal lubricants and moisturizers, and hot flash and sleep remedies. Geri has had a three-decade career in women's health, working at the top levels of the pharmaceutical industry as well as founding her own companies. She has amazing stories to tell about the business of menopause, about the science behind hormone therapy and various products. We talk about everything from clinical trials to letting your hair go gray.

Highlights:

• Hormones sure, but women need options for individual symptoms
• The problem with a lot of vaginal moisturizers and hormone therapies
• How we are conditioned to take hormones and what might be the problem with that
• There are risks to hormone therapy – don’t let anyone tell you there’s not
• Why you need to fact check influencers, doctors on social media + your own doctor (PubMed is a great place to start)
• What we’ve finally figured out about women – and how to use that power
• We’ve finally reached a North American menopause revolution – and what needs to follow
• A peek inside her experience as one of the only women inside Big pharma at the C-suite level
• How the traditionally male-dominated Big Pharma continues to impact women’s health care today
• The anecdote you have to hear about the possibility of a testosterone patch from Geri’s former career
• The one big thing pharmaceutical companies need to do in developing products for women safely
• Her peri/menopause experience + philosophy
• Becoming a certified silver sister
Where to find FemmePharma and Mia Vita:
Web: FemmePharma.com
Instagram: @FemmePharma

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A solo episode where I talk about my mom.
She died right after she turned 53.
I am about to turn 53.
This has been a thing.
This is a thing for people.
Also: the gifts my mom gave me by dying young, the message I want to give you about living courageously, with fear, honoring the ones we love that we lose, energy, breaking generational barriers and some funny stories, possibly involving cakes intentionally made to resemble poop.

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