Lean Mass Hyper Responder, Bile Reflux, Diverticulitis Recovery | THRR082

07/30/21 • 54 min

A2 Milk for Kids; Lean Mass Hyper Responder with Type 1 Diabetes; Fucoxantin and CLA for Fat Loss; Bile reflux, Gallbladder, Woe; Post-Diverticulitis Recovery Diet

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News topic du jour:

"Original antigenic sin”: A potential threat beyond the development of booster vaccination against novel SARS-CoV-2 variants

"A phenomenon called “original antigenic sin” (OAS) was firstly proposed by Francis 6 in 1960. This phenomenon occurs in the second exposure of the immune system to a similar pathogen to which it has previously been exposed. In this situation, the immune system progresses to the memory response, generating cross-reactive antibodies that may not be effective against the new pathogen. 7 In addition, it has been speculated that overproduction of memory B cells could compromise the activation of naïve B cells capable of producing efficient and novel antibodies. 8 In this way, OAS can trigger immune evasion of the emerging variants in those who had been affected by or vaccinated against former versions of the pathogen. In the context of coronaviruses, cross-neutralization is a rare event, but cross-reactivity in antibody binding to spike protein is common in SARS-CoV-2 and SARS-CoV. 9 Furthermore, some degrees of cross-reactivity have also been demonstrated between seasonal coronaviruses and SARS-CoV-2. 10 Aydillo et al 11 reported a strong back-boosting of antibodies in SARS-CoV-2–infected patients previously infected with human β-coronaviruses. Interestingly, a negative correlation was observed between pre-exposure to human β-coronaviruses and induction of antibodies against SARS-CoV-2, mentioning the reduction of de novo humoral immune response and occurrence of OAS in patients with pre-existing immunity against related coronaviruses. 11

The impact of OAS in developing vaccines is of paramount interest. The hypothesis of antigenic distance was proposed to explain how the efficacy of vaccines could be influenced by the difference or relatedness of prior vaccinations. This hypothesis is substantially evident in the case of dengue fever-related vaccine research. Once an individual is immunized against a dengue virus variant, the booster shot for the second variant is unlikely to be successful because it triggers only the original neutralizing antibodies rather than effective antibod...

A2 Milk for Kids; Lean Mass Hyper Responder with Type 1 Diabetes; Fucoxantin and CLA for Fat Loss; Bile reflux, Gallbladder, Woe; Post-Diverticulitis Recovery Diet

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News topic du jour:

"Original antigenic sin”: A potential threat beyond the development of booster vaccination against novel SARS-CoV-2 variants

Previous Episode

Milk Weight Gainer, Soy Based Cleaner, Saw Palmetto Supplement | THRR081

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News topic du jour:

A metabolomics comparison of plant‐based meat and grass‐fed meat indicates large nutritional differences despite comparable Nutrition Facts panels

https://www.nature.com/articles/s41598-021-93100-3.epdf?fbclid=IwAR0L6X7m4F2JlDHx1Z5QO3e6fp8aSjU19LBhD2u_PMKe5NIJmfDdtLCIf6I

1. Low Iron Diet [15:15]

Shawn says:

Hey Robb and Nicki,

About 18 months ago I found out I have hemochromatosis. I've been getting blood letting since and have my iron under 50 now. My question is about diet. Obviously my doctor doesn't want me eating alot of red meat, organ meat, or high iron seafoods. Am I going to start getting deficient in vitamins and nutrients (B12 etc.) Is there anything I can do diet wise to try and replace the vitamins and nutrients? Can you do a carnivore or Paleo diet without eating alot of red meat? Any thoughts would be appreciated. I'm confused as the best way to optimize my specific dietary needs. Thank you so much for the podcast and everything you two do.

Shawn

2. Using Milk for Calorie Surplus to Gain Weight [19:01]

Andy says:

Hi Robb and Nicki,

I'm a new Healthy Rebellion member and love it. I'm 42, 5'6" and weigh 140. Followed Robb since 5+ years of crossfit in my mid-30s. I have maybe 5 pounds of fat I could lose around my waste. Eat low carb and zero sugar...mostly meat/eggs, fruit and nuts. No "comorbidities". I don't have a big appetite and my body defaults to 135-140 lbs. My parents are also really small.

I've been thinking a lot about the importance of strength/muscle mass and aging. My dad has dropped probably 20 lbs and all of his muscle from early 60s to mid 70s. He's not physically active. Over the next few years I would like to get my weight up to a lean 155-160 and maintain at that weight as long as possible. If I starting aging at 135 lbs then I'm going to be in trouble.

I've begun a Starting Strength style linear progression with the basic barbell lifts. Lift 3x per week and add weight to the bar each time. I have a real hard time eating enough meat to maintain the calorie surplus it's going to take to gain the weight. I don't want to do it via carbs (rice/pasta/etc). I digest whole milk fine.

What are your thoughts on drinking 24-32 oz of milk per day to gain weight? Does pasteurized vs raw matter? Thoughts on long-term consumption? I'll probably have to keep it up to keep the weight on. Any other suggestions to add 300-500 calories to my diet besides "suck it up" and eat more?

Thanks.

Andy

3. Will Soy Based Bath Cleaner Affect My Backsquat? [23:17]

Kie says:

Hi Robb and Nicki,

Your podcast is great, it's changed the way I live my life for the better. Quick question if I may. My wife wants to switch to a soy based bath cleaner because it's good for the environment. Are the Xenoestrogens and Phytoestrogens leeched into my bathwater from this product going to affect my backsquat progress?

Thanks!

Kie (Tokyo, Japan)

http://www.iherb.com/Bio-Kleen-Soy-Cream-Cleaner-Kitchen-and-Bath-32-fl-oz-946-ml/23967

4. Saw Palmetto Supplement - Hoax Or Real Deal? [26:56]

Jared says:

Hey Robb,

I understand you get a lot of questions thrown your way, and often times most of my questions are answered from listening to the podcast or doing a little digging. But, every once in a while I get a question that causes me to ponder, "I wonder what Robb's opinion is?" A friend asked me if I know anything about Saw Palmetto, as he noticed it in a supplement called Ageless Male. I didn't know anything, but did some Googling and noticed that it's touted for its prostate and hormonal benefits (including testosterone support and improved muscle strength). Seems just as effective as deer antler velvet to me. Anyway, what feedback could you provide as to how beneficial this could be for my aging 50 year old friend? Anything is greatly appreciated.

https://pubmed.ncbi.nlm.nih.gov/11337315/

5. A Kids Audiobook Series, PMR & Keto, and Mouthwash [29:23]

Tamara says:

...

Next Episode

DNA Testing For Ideal Diet/Exercise, Nitrates/Nitrites, “Normal” Blood Pressure | THRR083

DNA Testing For Ideal Diet/Exercise, Body Composition Scales, Nitrates/Nitrites, Calcium Intake, What is "Normal" Blood Pressure?

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News topic du jour:

After being dismissed by doctors, mom of child with Down syndrome makes a discovery

1. DNA Testing For Ideal Diet/Exercise [12:01]

Trevor says:

Dear Robb and Nicki,

I really enjoy your podcast. I've gone from only listening when the topic looked interesting to listening to every episode because there's always something good or interesting. I appreciate your alls' free thinking mindset and news topics. I've also bought a big ol' box of LMNT and really like the Watermelon flavor.

My question is about DNA testing. Do you think there's any value to having this done to determine ideal diet, exercise, and overall lifestyle cues? Or is trial and error a better route? If you think testing is valuable, is there a company you can recommend?

Thanks,

Trevor

2. Body Composition Scales [20:21]

Danny says:

Are any of the scales on the market that claim to measure your body composition worth looking into or are they all pretty much bullshit

3. Nitrates/Nitrites [24:44]

Mackenzie says:

I've been thinking about my Nitrate/Nitrite consumption lately. The ideas around Nitrate/Nitrite seems to be a bit confusing because it's present in natural foods but also added to processed foods. I eat a fair bit of Kimchi, some deli meat, condiments like Sriracha - in addition to loving things like beets, spinach, celery..etc. I don't appear to have any adverse reactions to Nitrate/Nitrite consumption, so with that said, would it be better for my overall health to cut out those more processed foods?

Thanks!

4. Calcium Intake [29:04]

Megan says:

Hi Robb and Nicki, I love your show! I had a question regarding getting adequate calcium when not eating dairy. I eat a whole food diet, no processed foods (no gluten, dairy, soy, or corn). I eat lots of grass fed beef, organic chicken thighs, wild shrimp, and wild scallops. I do not eat sardines or fish bones though. Is it possible to get enough calcium when not consuming dairy products or fish bones? Thanks for your time! Megan

5. What is "Normal" Blood Pressure? [33:02]

Amy says:

Hey Guys!

So I went to donate blood today and was refused because my blood pressure was too low. Eek! I usually run about 90-something over 60-something, which I realize is already pretty low. Today, I was 88/55, as measured by a machine and not manually by the lab tech. (Don't know if that makes it more or less accurate.) So it was what we might call "freakishly low," but the thing is, I FELT FINE. Physical energy was good, mental outlook was all right -- no issues. Nothing about how I felt all day would suggest that my BP was "too low." (I went to donate around 12pm.)

So my question is, for a mostly low-carbing, very fit 35-year-old woman, what is a "normal" blood pressure, and more important, is BP another parameter we should add to blood glucose, HbA1C, triglycerides, and other markers whose "normal" ranges are based on the sedentary, sick, and inflamed masses and therefore reflect what's *common* more than what's normal/optimal?

(I'm reminded of how Robb's wife's ob/gyn was surprised at what a relatively "easy" pregnancy she had. Well, yeah, compared to all the walking, talking chronic disease bags he/she normally sees, Nikki's health was off the charts. *Of course* she had a better time of it.)

I do realize that when it comes to BP, there *is* such a thing as too low, but I'm wondering what that is, as long as someone feels no adverse effects. (Kind of like glucose...I've tested and seen myself in the mid-to-high 60s and felt FINE. Yay, fat adaptation.)

Hunter-gatherers as models in public health

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