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STEM-Talk - Episode 43: Jeff Volek explains the power of ketogenic diets to reverse type 2 diabetes

Episode 43: Jeff Volek explains the power of ketogenic diets to reverse type 2 diabetes

08/01/17 • 67 min

STEM-Talk

Today’s episode features an important interview with Dr. Jeff Volek, a researcher who has spent the past 20 years studying how humans adapt to carbohydrate-restricted diets. His most recent work, which is one of the key topics of today’s interview, has focused on the science of ketones and ketogenic diets and their use as a therapeutic tool to manage insulin resistance.

In 2014, Volek became a founder and the chief science officer of Virta Health, an online specialty medical clinic dedicated to reversing diabetes, a chronic disease that has become a worldwide epidemic. The company’s ambitious goal is to reverse type 2 diabetes in 100 million people by 2025.

Earlier this year, The JMIR Diabetes Journal published a study coordinated by Volek and Virta that showed people with type 2 diabetes can be taught to sustain adequate carbohydrate restriction to achieve nutritional ketosis, thereby improving glycemic control, decreasing medication use, and allowing clinically relevant weight loss. These improvements happened after just 10 weeks on the program that Virta designed for people.

In addition to his role at Virta, Volek is a registered dietitian and full professor in the department of human sciences at Ohio State University. He is a co-author of “The New Atkins for a New You,” which came out 2010 and spent 16 weeks on The New York Times best-seller list. The book is an updated, easier-to-use version of Dr. Robert Atkins’ original 1972 book, “Dr. Atkins’ Diet Revolution.”

Volek has co-authored four other books, including “The Art and Science of Low Carbohydrate Living” and “The Art and Science of Low Carbohydrate Performance.” Both books are co-authored with and delve somewhat deeper than “The New Atkins” did into the science and application of low-carb diets.

Volek received his bachelor’s degree in dietetics from Michigan State University in 1991. He went on to earn a master’s in exercise physiology and a PhD in kinesiology and nutrition from Pennsylvania State University. He has given more than 200 lectures about his research at scientific and industry conferences in a dozen countries. In addition to his five books, he also has published more than 300 peer-reviewed scientific papers.

Although numerous studies have confirmed the validity and safety of low-carb and ketogenic diets, Volek and others who support carbohydrate restriction are often criticized for being so one-sided that their work comes across as more advocacy than science. But in “The Art and Science of Low Carbohydrate Living,” Volek writes:

“What is the proper response when three decades of debate about carbohydrate restriction have been largely one-sided and driven more by cultural bias than science? Someone needs to stand up and represent the alternate view and science.”

As Volek explains in episode 42 of STEM-Talk, this has become his mission.

Links:

“New Atkins for a New You” — http://amzn.to/2uOjLkF

“The Art and Science of Low-Carbohydrate Living”– http://amzn.to/2hh1W9k

“The Art and Science of Low-Carbohydrate Performance” — http://amzn.to/2f2oPMV

New York Times article:
https://www.nytimes.com/2017/04/11/well/live/tackling-weight-loss-and-diabetes-with-video-chats.html?_r=0

JMIR DIABETES paper:
http://assets.virtahealth.com/docs/Virta_Clinic_10-week_outcomes.pdf

https://www.virtahealth.com

Show notes:

3:016: Ken and Dawn welcome Jeff to the show.

3:32: Dawn asks Jeff when and how he first became interested in science.

5:24: When Jeff was studying to be a dietitian, he was looking at a low-fat, high-carb diet. But when he began to work with diabetics, something did not seem right. Dawn asks Jeff if that is what led him to begin studying low-carb diets.

6:39: Ken comments on how diabetes is perhaps the greatest healthcare challenge we face as a society, which drives costs to more than $300 billion a year.

7:59: Dawn asks Jeff about the effectiveness of traditional treatment and management approaches for people with diabetes.

8:27: Dawn asks Jeff to talk about Virta Health, a company Jeff helped found, and a recent paper and JMIR Diabetes Journal. The paper reported on the results of a study that looked at whether sustained carbohydrate restriction and nutritional ketosis could be part of a comprehensive intervention that would allow people with type 2 diabetes to improve their health.

11.54: Dawn asks Jeff why this approach would work at the cellular level, ...

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Today’s episode features an important interview with Dr. Jeff Volek, a researcher who has spent the past 20 years studying how humans adapt to carbohydrate-restricted diets. His most recent work, which is one of the key topics of today’s interview, has focused on the science of ketones and ketogenic diets and their use as a therapeutic tool to manage insulin resistance.

In 2014, Volek became a founder and the chief science officer of Virta Health, an online specialty medical clinic dedicated to reversing diabetes, a chronic disease that has become a worldwide epidemic. The company’s ambitious goal is to reverse type 2 diabetes in 100 million people by 2025.

Earlier this year, The JMIR Diabetes Journal published a study coordinated by Volek and Virta that showed people with type 2 diabetes can be taught to sustain adequate carbohydrate restriction to achieve nutritional ketosis, thereby improving glycemic control, decreasing medication use, and allowing clinically relevant weight loss. These improvements happened after just 10 weeks on the program that Virta designed for people.

In addition to his role at Virta, Volek is a registered dietitian and full professor in the department of human sciences at Ohio State University. He is a co-author of “The New Atkins for a New You,” which came out 2010 and spent 16 weeks on The New York Times best-seller list. The book is an updated, easier-to-use version of Dr. Robert Atkins’ original 1972 book, “Dr. Atkins’ Diet Revolution.”

Volek has co-authored four other books, including “The Art and Science of Low Carbohydrate Living” and “The Art and Science of Low Carbohydrate Performance.” Both books are co-authored with and delve somewhat deeper than “The New Atkins” did into the science and application of low-carb diets.

Volek received his bachelor’s degree in dietetics from Michigan State University in 1991. He went on to earn a master’s in exercise physiology and a PhD in kinesiology and nutrition from Pennsylvania State University. He has given more than 200 lectures about his research at scientific and industry conferences in a dozen countries. In addition to his five books, he also has published more than 300 peer-reviewed scientific papers.

Although numerous studies have confirmed the validity and safety of low-carb and ketogenic diets, Volek and others who support carbohydrate restriction are often criticized for being so one-sided that their work comes across as more advocacy than science. But in “The Art and Science of Low Carbohydrate Living,” Volek writes:

“What is the proper response when three decades of debate about carbohydrate restriction have been largely one-sided and driven more by cultural bias than science? Someone needs to stand up and represent the alternate view and science.”

As Volek explains in episode 42 of STEM-Talk, this has become his mission.

Links:

“New Atkins for a New You” — http://amzn.to/2uOjLkF

“The Art and Science of Low-Carbohydrate Living”– http://amzn.to/2hh1W9k

“The Art and Science of Low-Carbohydrate Performance” — http://amzn.to/2f2oPMV

New York Times article:
https://www.nytimes.com/2017/04/11/well/live/tackling-weight-loss-and-diabetes-with-video-chats.html?_r=0

JMIR DIABETES paper:
http://assets.virtahealth.com/docs/Virta_Clinic_10-week_outcomes.pdf

https://www.virtahealth.com

Show notes:

3:016: Ken and Dawn welcome Jeff to the show.

3:32: Dawn asks Jeff when and how he first became interested in science.

5:24: When Jeff was studying to be a dietitian, he was looking at a low-fat, high-carb diet. But when he began to work with diabetics, something did not seem right. Dawn asks Jeff if that is what led him to begin studying low-carb diets.

6:39: Ken comments on how diabetes is perhaps the greatest healthcare challenge we face as a society, which drives costs to more than $300 billion a year.

7:59: Dawn asks Jeff about the effectiveness of traditional treatment and management approaches for people with diabetes.

8:27: Dawn asks Jeff to talk about Virta Health, a company Jeff helped found, and a recent paper and JMIR Diabetes Journal. The paper reported on the results of a study that looked at whether sustained carbohydrate restriction and nutritional ketosis could be part of a comprehensive intervention that would allow people with type 2 diabetes to improve their health.

11.54: Dawn asks Jeff why this approach would work at the cellular level, ...

Previous Episode

undefined - Episode 42: Tom Jones discusses defending Earth against the threat of asteroids

Episode 42: Tom Jones discusses defending Earth against the threat of asteroids

Frequent STEM-Talk listeners will more than likely recognize today’s guest, veteran NASA astronaut Tom Jones, who joins us today to talk about the threat of near-Earth asteroids.

Tom occasionally helps co-host STEM-Talk. But for episode 42, regular co-hosts Ken Ford and Dawn Kernagis turn the microphone around to interview Tom about his days as an astronaut, planetary defense and asteroids.

It’s a topic, as you will hear, that Tom is quite passionate about. He also has a great deal of expertise in the field. Before he became an astronaut, Tom earned a doctorate in planetary science from the University of Arizona in 1988. He’s also a graduate of the United States Airforce Academy. His research interests range from the remote sensing of asteroids to meteorite spectroscopy to applications of space resources.

He became an astronaut in 1991 and received the NASA Space Flight Medal in 1994, 1996, and 2001. He also received the NASA Exceptional Service Award in 1997 and again in 2000. In 1995, he received the NASA Outstanding Leadership Medal.

Tom logged 52 days in space, including three space walks totaling more than 19 hours. He is the author of several books, including Sky Walking: An Astronauts Memoir, which the Wall Street Journal named as one of the five best books about space. His latest book is Ask the Astronaut: A Galaxy of Astonishing Answers to Your Questions about Space.

Below are links to Tom’s books as wells the STEM-Talk interview with Pascal Lee, which Ken refers to while interviewing Tom.

Links:

Pascal Lee interview: http://www.ihmc.us/stemtalk/episode-17/

New Yorker article: http://www.newyorker.com/magazine/2011/02/28/vermin-of-the-sky

TFPD Report: http://www.ihmc.us/wp-content/uploads/2017/07/TFPD-FINAL-Report-to-NAC-10-6-10_v2.pdf

Tom Jones books:

“Sky Walking” – http://amzn.to/2t8dSQn

“Ask the Astronaut” – http://amzn.to/2vhUxZD

“Complete Idiots Guide to NASA” – http://amzn.to/2uWZHun

“Planetology” – http://amzn.to/2unXgnP

Show notes:

3:36: Ken and Dawn welcome Tom to the show.

4:11: Ken comments on the interesting path that Tom has travelled throughout his life and asks Tom to give a synopsis of his path of reinvention.

6:56: Dawn asks Tom to talk about the goals and highlights of the four shuttle missions he went on.

3:39: Dawn welcomes Tom as a guest on STEM-Talk.

9:23: Dawn comments on how Tom no longer flies in space, but he and some of his colleagues are now involved in another space mission that could save the Earth or a large part of it from destruction. Dawn then asks Tom how he became interested in planetary defense from asteroids.

11:30: Ken asks Tom to explain the differences between asteroids, comets, meteoroids, meteors, and meteorites.

13:37: Ken asks Tom how he would define a near-earth asteroid.

14:06: Dawn asks Tom how frequently asteroids strike the Earth.

16:27: Dawn asks Tom how likely she is to die in an asteroid catastrophe, statistically speaking.

18:27: Dawn discusses an article on planetary defense titled, Vermin of the Sky, published in The New Yorker in February of 2011. She comments on how Ken is quoted in the article as saying, “The very short perspective we have as humans makes the threat of asteroids seem smaller than it is. People of all sorts find it easier to kick the can down the road and hope for a mystical solution.”

20:04: Ken comments on how in the same article Clark Chapman notes that “Unlike Hurricane Katrina, we can do something about an asteroid, the question is whether we would rather be wrong in overprotecting or wrong in under protecting”. Ken then points out that one can imagine a near societal collapse should it be announced that, with high confidence, an asteroid was on a collision course with Earth, and that as a society we have no means to deflect it. Humans, Ken adds, would come to envy the dinosaurs who had no time to ruminate about their fate. Ken asks Tom if he can even imagine the societal disruption of such an announcement.

21:50: Dawn discusses how in January of this year the U.S. Government released a strategy for preparing for a Near-Earth Object (NEO) impact. She then asks Tom if he thinks the strategy is on the right track.

23:29: Dawn asks Tom to give a sense of how NASA deals with the asteroid hazard today.

25:04: Dawn asks Tom i...

Next Episode

undefined - Episode 44: Jerry Pratt discusses the evolution and future of humanoid robots and bipedal walking

Episode 44: Jerry Pratt discusses the evolution and future of humanoid robots and bipedal walking

Today’s podcast features Ken Ford and Dawn Kernagis interviewing their colleague, Dr. Jerry Pratt, a senior research scientist at IHMC who heads up the institute’s robotics group. In 2015, Jerry led an IHMC team that placed second out of 23 teams from around the world in the first-ever DARPA Robotics Challenge. IHMC also placed first in the competition which featured humanoid robots that primarily walked bipedally and first among all U.S. teams.

Jerry is a graduate of MIT, where he earned a doctorate in electrical engineering and computer science in 2000. As a graduate student at MIT, Jerry built his first robot which was also one of the first bipedal robots that could compliantly walk over rough terrain.

As you will learn in today’s interview, it was called “Spring Turkey” and is on display in MIT’s Boston museum. The second robot he built as a graduate student was called “Spring Flamingo,” and is on display in the lobby of IHMC’s Fred Levin Center in Pensacola.

After graduation, Jerry and some MIT colleagues founded a small company called Yobotics, which specialized in powered prosthetics, biomimetic robots, simulation software and robotic consulting.

He joined IHMC in 2002 and has become a well-known expert in bipedal walking. His algorithms are used in various robots around the world. Recent work on fast-running robots has resulted in ostrich-inspired running models and robot prototypes that are currently believed to be the fastest running robots in the world.

Jerry has six U.S. patents and was inducted into the Florida Inventors Hall of Fame in 2015. He lives in Pensacola with his wife Megan and their two children. He and he wife founded a science museum called the Pensacola MESS Hall, which stands for math, engineering, science, and stuff. The MESS Hall is a hands-on science museum for all ages that just celebrated it’s five-year anniversary.

Show notes:

4:37: Ken and Dawn welcome Jerry to the show

4:54: Dawn asks Jerry to talk about the time he once stole a science book from school.

5:45: Dawn asks Jerry to discuss his first invention, the knockout keyless door lock, that he came up with for his tree fort when he was a teen.

6:21: Dawn asks Jerry if he recalls his first computer program he wrote on the Commodore 64.

6:47: Ken comments on how in addition to writing computer programs, Jerry had an interest in electronics, particularly Heathkits.

7:08: Dawn discusses how Jerry played a lot of sports as a kid, going on to run varsity track and cross country at MIT.

7:46: Dawn asks Jerry if it was as an undergrad or a graduate student that he first became interested in robotics.

8:20: Ken discusses the first two robots Jerry put together: Spring Turkey then Spring Flamingo. He then asks Jerry to talk about the machines and how he came up with the names.

9:16: Dawn comments on how a few of Jerry’s colleagues have mentioned that much of our understanding of dynamic walking is still based on some of the original work Jerry did at MIT, and she then asks Jerry to talk about that work.

10:03: Ken asks Jerry to talk about how he and his wife, Megan Benson, met.

10:54: Ken asks Jerry to discuss the experience of co-founding Yobotics, which specialized in powered prosthetics, biomimetic robots, simulation software, and robot consulting, with his colleagues at MIT.

11:36: Dawn discusses the growth of robotics at IHMC since Jerry joined the team. She then asks Jerry to give a summary on the types of robots that he and his colleagues have been working on over the last 14 years at IHMC.

13:55: Dawn asks Jerry to talk about the books he often reads on organizational culture and teambuilding.

15:08: Dawn comments on how she has heard that Jerry is one of the worst motivational speakers ever and asks if it is true.

15:28: Ken comments on all of the work that Jerry and the IHMC team put into the DARPA Robotics Challenge, where they placed second in the world and first among the United States teams. He then asks Jerry to describe the experience.

16:24: Ken asks Jerry what it would look like if he were designing a new challenge focused on robotic mobility.

17:03: Dawn comments on a story about Jerry’s daughter Annie telling her kindergarten teacher that her daddy builds robots that fall down.

17:42: Dawn discusses how Jerry has spent most of his career thinking about how humans balance themselves to keep from falling, and how we use these strategies to help balance robots. She then asks Jerry to walk through that process.

18:35: Dawn asks Jerry what happens when a robot recovers its balance.

19:13: Dawn comments on how Jerry’s focus has been on bipedal walking. She then goes on to ask why engineers design robots with legs, and even more specifically, two legs.

20:03: Ken states that one of the advantages ...

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