
Serotonin: does it make you Happy, Narcissistic or....? Feel Good Biochemistry Part 2 | Episode 14
06/20/23 • 123 min
In this Episode which became Part 2 in our 'Adjusting Hormones and Neurochemicals to Feel Happy' Series, we discuss Serotonin: Is it really the key to happiness and relaxation, or a stress chemical which can make you feel suicidal or narcissistic?
We explore the options, reflecting on Ray Peat's research into the area of which chemicals keep us young and happy and which ones make us stressed and age prematurely, as well as the potential implications to a spiritual or religious practice.
We end with a review of everything we've covered so far, and how it ties into the Polyvagal theory, as we explore which hormones and chemicals may be responsible for creating the Ventral Vagal, Sympathetic, and Dorsal Vagal Modes of the Central Nervous System, how we can end up feeling bad most of the time, and the best path back to feeling good most of the time.
References from this episode:
RP - Feel Good 1
RP - Metabolism
RP - Digestion
RP - Stress & Anxiety
RP - Thyroid
The High Serotonin Personality
https://men-elite.com/2019/01/17/the-high-serotonin-personality/
Serotonin inhibition of the NMDA receptor/nitric oxide/cyclic GMP pathway in human neocortex slices: involvement of 5-HT2C and 5-HT1A receptors
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1572268/
Serotonin-prefrontal cortical circuitry in anxiety and depression phenotypes: pivotal role of pre- and post-synaptic 5-HT1A receptor expression
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047678/
Serotonin and decision making processes
https://www.sciencedirect.com/science/article/abs/pii/S0149763411001114
Serotonin The Fraudulent Antidepressant
https://men-elite.com/2020/04/24/serotonin-the-fraudulent-anti-depressant/
Investigating the Molecular Basis of Major Depressive Disorder Etiology
https://nyaspubs.onlinelibrary.wiley.com/doi/10.1196/annals.1410.018
Serotonergic Systems, Anxiety, and Affective Disorder
https://nyaspubs.onlinelibrary.wiley.com/doi/abs/10.1196/annals.1410.004
Metabolic, Molecular, and Behavioral Effects of Western Diet in Serotonin Transporter-Deficient Mice: Rescue by Heterozygosity?
https://pubmed.ncbi.nlm.nih.gov/32132889/
Serotonin and Sleep: Molecular, Functional, and Clinical Aspects
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675905/
Parasite Rex
https://www.amazon.com/Parasite-Rex-Bizarre-Dangerous-Creatures/dp/074320011X
Sadh Guru - Inner Engineering
In this Episode which became Part 2 in our 'Adjusting Hormones and Neurochemicals to Feel Happy' Series, we discuss Serotonin: Is it really the key to happiness and relaxation, or a stress chemical which can make you feel suicidal or narcissistic?
We explore the options, reflecting on Ray Peat's research into the area of which chemicals keep us young and happy and which ones make us stressed and age prematurely, as well as the potential implications to a spiritual or religious practice.
We end with a review of everything we've covered so far, and how it ties into the Polyvagal theory, as we explore which hormones and chemicals may be responsible for creating the Ventral Vagal, Sympathetic, and Dorsal Vagal Modes of the Central Nervous System, how we can end up feeling bad most of the time, and the best path back to feeling good most of the time.
References from this episode:
RP - Feel Good 1
RP - Metabolism
RP - Digestion
RP - Stress & Anxiety
RP - Thyroid
The High Serotonin Personality
https://men-elite.com/2019/01/17/the-high-serotonin-personality/
Serotonin inhibition of the NMDA receptor/nitric oxide/cyclic GMP pathway in human neocortex slices: involvement of 5-HT2C and 5-HT1A receptors
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1572268/
Serotonin-prefrontal cortical circuitry in anxiety and depression phenotypes: pivotal role of pre- and post-synaptic 5-HT1A receptor expression
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047678/
Serotonin and decision making processes
https://www.sciencedirect.com/science/article/abs/pii/S0149763411001114
Serotonin The Fraudulent Antidepressant
https://men-elite.com/2020/04/24/serotonin-the-fraudulent-anti-depressant/
Investigating the Molecular Basis of Major Depressive Disorder Etiology
https://nyaspubs.onlinelibrary.wiley.com/doi/10.1196/annals.1410.018
Serotonergic Systems, Anxiety, and Affective Disorder
https://nyaspubs.onlinelibrary.wiley.com/doi/abs/10.1196/annals.1410.004
Metabolic, Molecular, and Behavioral Effects of Western Diet in Serotonin Transporter-Deficient Mice: Rescue by Heterozygosity?
https://pubmed.ncbi.nlm.nih.gov/32132889/
Serotonin and Sleep: Molecular, Functional, and Clinical Aspects
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675905/
Parasite Rex
https://www.amazon.com/Parasite-Rex-Bizarre-Dangerous-Creatures/dp/074320011X
Sadh Guru - Inner Engineering
Previous Episode

Adjusting Chemistry to Feel Good the Healthy Way: Dopamine, GABA, Serotonin, Oxytocin & more | Ep 13
We all want to feel better, but are the strategies we're currently using like caffeine, alcohol, nicotine and other legal and pharmaceutical drugs, and other addictive and compulsive habits, really the best options?
Or is there a more effective approach? Rather than go down the usual path you've heard many times before, like eat well, sleep well, exercise more etc, in this episode Elwin and Krissy take a different approach and ask the fundamental question:
What are the chemicals inside us that make us feel good? And how do we increase them in a way that is sustainable and long lasting, rather than temporary?
Along the way they discuss Dopamine, Serotonin, GABA, Glycine, Oxytocin, Testosterone, Progesterone, as well as the little known DHT and Allopregnanolone as they look for novel answers for substances to take that work better, and are safer and less toxic, than the chemicals that most of us are already taking on a daily basis.
References from this episode:
RP - Stress & Anxiety Episode - https://youtu.be/xApOAM30SpA
RP - Hormone Episode - https://youtu.be/UbFMD86seyI
RP - Metabolism Episode - https://youtu.be/y1kZFAqbbm0
You can find Elwin’s recommended Feeling Good Supplements here:
https://feelyounger.net/collections/mood-support
And remember to use code “REJUVENATEME” to tell them we sent you and to get 20% OFF your first order.
If you’d like to know which Genetic Factors are influencing your Happiness, go to
https://geneticinsights.co/happy
And use promo code “REJUVENATE” to tell Genetic Insights we sent you and get 20% OFF your first order.
You can follow Elwin on Twitter @therealelwin
And you can find Krissy on Twitter @KrissyHawkes
This Podcast does not contain medical advice. I am NOT a doctor. The contents of this Podcast, such as videos, text, graphics, images and other material are intended for entertainment, informational and educational purposes only and not for the purpose of rendering medical advice. The contents of this Podcast are not intended to substitute for professional medical advice, diagnosis or treatment.
Consult your physician for medical advice. Always seek the advice of a physician or qualified healthcare provider with any questions regarding a medical condition. Never disregard or delay seeking professional medical advice or treatment because of something you have heard on a Podcast. Before taking any medications, over-the-counter drugs, supplements or herbs, consult a physician for a thorough evaluation. A qualified physician should make a decision on each person’s medical history and current prescriptions.
Next Episode

Secrets to a Healthy Cardiovascular System? | Rejuvenate Podcast Episode 15
Why is Cardiovascular Disease so common in this day and age that it's the number 1 killer throughout most of the world? In this episode we explore the roots of Cardiovascular disease:
What is it?
What causes it?
And what can you do to help prevent it?
And what are the best tests you can do to measure your Cardiovascular health?
We look at Genetic Risk Factors, as well as Diet, Stress, and Lesser Known and Understood Causes that may actually be the root of the issue, and steps you can do to:
1 Improve Vasodilation in an healthy way
2 Reduce cholesterol in blood without negatively impacting hormone production
3 Reduce calcium build up in blood
4 Reduce excess fibrin and clotting factors
5 Reduce inflammation
6 Reduce Rigidity of the Arteries
7 Release any localized constrictions
References from this episode:
RP - Thyroid & Adrenals - https://youtu.be/D-uBXy3StYY
RP - Chronic Pain Part 1 - https://youtu.be/-6mcmXEHhJ4
RP - Chronic Pain Part 2 - https://youtu.be/tFpD4EQIZZo
RP - Stress & Anxiety - https://youtu.be/xApOAM30SpA
RP - Hormones - https://youtu.be/UbFMD86seyI
Counterstrain - https://counterstrain.com/
If you’d like to know which Genetic Factors are influencing your Cardiovascular Health, go to
https://geneticinsights.co/cardiohealth
And use promo code “REJUVENATE” to tell Genetic Insights we sent you and get 20% OFF your first order.
You can find Elwin’s recommended Metabolism and Anti Aging Supplements here: https://feelyounger.net/collections/heart-health
And remember to use code “REJUVENATEME” to tell them we sent you and to get 20% OFF your first order.
You can follow Elwin on Twitter @therealelwin
And you can find Krissy on Twitter @KrissyHawkes
The Rejuvenate podcast is dedicated to looking at the real root causes of premature aging, and what we can do to 'turn back the clock' and feel younger and healthier again.
Each episode will focus on a different area of health.
To begin with, episodes will be quite broad and just an overview of a big subject, then later the plan is to go more in depth, both with our hosts, and also guests, on more specific issues and give a comprehensive plan for each.
Make sure you Like and Subscribe so you don't miss an episode, and if you have any feedback, questions or requests for future episodes, leave a comment underneath the video and Krissy or Elwin will do their best to reply personally.
Disclaimer:
This Podcast does not contain medical advice. I am NOT a doctor. The contents of this Podcast, such as videos, text, graphics, images and other material are intended for entertainment, informational and educational purposes only and not for the purpose of rendering medical advice. The contents of this Podcast are not intended to substitute for professional medical advice, diagnosis or treatment.
Consult your physician for medical advice. Always seek the advice of a physician or qualified healthcare provider with any questions regarding a medical condition. Never disregard or delay seeking professional medical advice or treatment because of something you have heard on a Podcast. Before taking any medications, over-the-counter drugs, supplements or herbs, consult a physician for a thorough evaluation. A qualified physician should make a decision on each person’s medical history and current prescriptions.
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