
Methylene Blue in 10 Minutes
09/02/23 • 9 min
Watch the full-length video here: https://www.youtube.com/watch?v=XhgGGbdw4zE&t=8621s
Get my free 51--page report, Methylene Blue: Biohacker's Delight or Playing With Fire?, here:
https://chrismasterjohnphd.substack.com/p/the-guide-to-methylene-blue
Watch the full-length video here: https://www.youtube.com/watch?v=XhgGGbdw4zE&t=8621s
Get my free 51--page report, Methylene Blue: Biohacker's Delight or Playing With Fire?, here:
https://chrismasterjohnphd.substack.com/p/the-guide-to-methylene-blue
Previous Episode

Methylene Blue: Biohacker's Delight, or Playing With Fire?
Get the written and referenced version here:
https://chrismasterjohnphd.substack.com/p/the-guide-to-methylene-blue
This is a 51-page guide in which you will learn the following:
The Origin of Methylene Blue
The Entry of Methylene Blue Into Medicine
From Malaria to Many Uses in Medicine
How Methylene Blue Works
A Redox-Reactive Dye
The Blue Bottle Experiment
Methylene Blue Radicals, Photoexcited States, and Demethylated Metabolites
Methylene Blue Can Oxidize and Reduce Many Targets
Methylene Blue Can Rewire the Mitochondrial Respiratory Chain
Rewiring the Respiratory Chain Does Not Make It Better
Methylene Blue Increases Hydrogen Peroxide Hydrogen Peroxide Kills Microbes, Has Hormetic Benefits, But Is Still Ultimately Toxic
Methylene Blue Causes Redox Cycling of Hemoglobin Methylene Blue Is a Strong Monoamine Oxidase A Inhibitor
Methylene Blue Inhibits Nitric Oxide Synthase Mechanistic Conclusions Is Methylene Blue Fundamentally Hormetic?
Methylene Blue Fails in Alzheimer’s, and Causes a Worrisome Side Effect
Whether Methylene Blue Helps Or Hurts Depends on Whether You Need It
Natural Alternatives for Hormesis and Rewiring the Respiratory Chain
Who Should Use Methylene Blue?
Once more you can get it here:
https://chrismasterjohnphd.substack.com/p/the-guide-to-methylene-blue
Next Episode

Why Should Postprandial Glucose Be Kept Under 140 mg/dL? | Masterjohn Q&A Files #323
Question: Why should postprandial blood glucose be kept under 140 milligrams per deciliter? Short Answer: When blood glucose rises above 140 mg/dL, this is the approximate point at which it spills into the polyol pathway at a greater-than-normal rate, which represents a suboptimal state of metabolism that is likely to hurt antioxidant status and compromise detoxification pathways as well as the recycling of vitamin K and folate. It must be kept in mind that a healthy person will adapt to glycemic loads they consume regularly. Thus, a one-time spike above 140 mg/dL should never be used to conclude anything whatsoever. Only repeated spikes above this level with repeated consumption of the same glycemic load over several days to several weeks should be used as a cause for concern.
This is a clip from a live Q&A session open to CMJ Masterpass members. In addition to this episode, you can access two other free samples using this link:
https://chrismasterjohnphd.substack.com/p/questions-on-blood-glucose-and-oxalate
In that batch of free episodes you will also find the answer to this question:
- How can I protect against oxalates?
If you want to become a Masterpass member so you can participate in the next live Q&A, or so you can have access to the complete recording and transcript of each Q&A session, you can save 10% off the subscription price for as long as you remain a member by using this link to sign up:
https://chrismasterjohnphd.substack.com/qanda
Learn more about the Masterpass here:
https://chrismasterjohnphd.substack.com/about
This snippet is from the April 12, 2023 AMA. The full recording and transcript is reserved for Masterpass members. Here is a preview of what’s included:
- What Causes Hypercholesterolemia and Does It Matter?
- How to Reverse Coronary Calcification?
- How to do a comprehensive nutritional screening
- How long after eating improperly cooked egg whites should I wait to take biotin?
- Is the extrusion process as harmful as some claim?
- How long can one fast before micronutrient deficiencies become an issue?
- Do B vitamins compete with each other for absorption?
- Why is thirst a symptom of diabetes?
- Do I agree with Peter Attia that ApoB should be driven as low as pharmacologically possible?
- During a fast, does the body break down muscle?
- How do you rest and refeed your brain?
- Why would someone have high RBC magnesium but low serum magnesium?
- GLA deficiency?
- Should we eat for our ethnicity?
- How convincing are polyphenol studies?
- Can coronary calcium be driven by oxalate?
- Citrulline for vasodilation
- How to reduce catabolism
- Rapid-fire run-through of orphaned questions from the submission contest, including a detailed look at Nadia’s thyroid numbers
Here’s a link to the full AMA: https://chrismasterjohnphd.substack.com/p/recording-and-transcript-of-the-april
Access the show notes, transcript, and comments here.
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