
Endometriosis is a disease of immune dysfunction
03/20/22 • 12 min
Endometriosis is an inflammatory disease that’s affected by hormones but is not caused by hormones. Instead, endometriosis is, at least in part, a disease of immune dysfunction.
In this episode, Lara discusses some of the new endometriosis research including:
- the link with genes that increase the risk of autoimmune disease
- the role of a bacterial toxin called lipopolysaccharide or LPS, and
- new targets for natural immune-modulating treatment.
Links to:
Endometriosis is an inflammatory disease that’s affected by hormones but is not caused by hormones. Instead, endometriosis is, at least in part, a disease of immune dysfunction.
In this episode, Lara discusses some of the new endometriosis research including:
- the link with genes that increase the risk of autoimmune disease
- the role of a bacterial toxin called lipopolysaccharide or LPS, and
- new targets for natural immune-modulating treatment.
Links to:
Previous Episode

Why PCOS cannot be diagnosed by ultrasound
Were you told you have polycystic ovary syndrome or PCOS based on a pelvic ultrasound? That may or may not be an accurate diagnosis because PCOS cannot actually be diagnosed or ruled out with ultrasound.
In this episode, Lara discusses PCOS including:
- why PCOS is an umbrella term
- the difference between polycystic ovaries and ovarian cysts, and
- why some women with undereating and endometriosis are being mistakenly told they have PCOS.
Links to:
- Blog post: PCOS cannot be diagnosed (or ruled out) by ultrasound
- Blog post about the 4 types of PCOS.
- Citation for the quote about polycystic ovaries: Diagnosis of Polycystic Ovary Syndrome: Which Criteria to Use and When?
- Lara's forum where you can post a comment or suggest a topic for a future episode.
Next Episode

A safer type of hormone therapy
If you're going to take hormone therapy, it's safer to take hormones that are identical to human hormones. In other words, hormones that are body-identical or bioidentical. The concept of bioidentical used to be controversial but is now conventional and mainstream.
In this episode, Lara discusses hormone therapy including:
- why the concept of bioidentical was controversial when it didn't need to be
- oral micronized progesterone for heavy periods, mood, sleep, and perimenopausal migraines, and
- some facts about body-identical estrogen (four uncontroversial things and one controversial).
Links:
- The crucial difference between progesterone and progestins
- Cyclic progesterone therapy for PCOS
- The central role of ovulatory disturbances in the etiology of androgenic polycystic ovary syndrome (PCOS)—Evidence for treatment with cyclic progesterone
- Blog post with a list of body-identical brand names
- Online workshop: Metabolic health and vitality for women over 40
Lara Briden's Podcast - Endometriosis is a disease of immune dysfunction
Transcript
Endometriosis is an inflammatory disease that’s affected by hormones but is not caused by hormones. Instead, endometriosis is, at least in part, a disease of immune dysfunction.
Welcome back to the podcast. I’m your host Lara Briden, a naturopathic doctor and author of the books period repair manual and hormone repair manual. And this episode is about a disease I thought I already knew quite a lot about. After all, I’ve treated endometriosis for 25 years and written about it on my bl
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