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Ketogeek's Podcast - 43. Science of Obesity & Why Carbohydrate-Insulin Model of Obesity is Wrong | Stephan Guyenet, PhD

43. Science of Obesity & Why Carbohydrate-Insulin Model of Obesity is Wrong | Stephan Guyenet, PhD

Explicit content warning

07/21/18 • 86 min

Ketogeek's Podcast

Obesity is a complicated problem and the solution may lie in a multi-prong approach. We look at what the science tells us about obesity, how various properties of foods can impact consumption, discuss the Carbohydrate Insulin Hypothesis and understand how the brain and body responds to an obesogenic environment.

Bio:

Stephan J. Guyenet, PhD is a former neuroscience and obesity researcher and author of the book The Hungry Brain: Outsmarting the Instincts That Make Us Overeat, which was named one of the best books of 2017 by Publishers Weekly. His research has been cited more than 2,000 times by his scientific peers. His writing and speaking focus on the brain circuits that regulate eating behavior and body fatness, and how we can work with them to sustainably manage our waistlines.

Time Stamps:

12:45 – Stephan’s journey into neuroscience and obesity research

16:06 – What caused obesity in humans?

20:22 – The connection between smoking and obesity?

22:32 – Why does every new diet trend such as paleo fail to reverse obesity crisis?

30:31 – Why focusing purely on taste and flavor to gauge food could be obesogenic.

36:36 – Why pure sugar, pure fat and pure sugar/fat are difficult to consume but in the right combination can be addictive and be overconsumed?

45:49 – How sensory variety could lead to overconsumption

48:40 – NUSI study and why Carbohydrate Insulin Hypothesis probably isn’t the sole driver of obesity

59:39 – Can eating fat raise insulin over time?

1:04:04 – How the food industry is incentivized to create obesogenic foods

1:08:11 – What drives cravings?

1:10:45 – Is short term overconsumption a good predictor of long term overconsumption?

1:14:04 – Does sugar addiction exist?

1:17:20 – Understanding what kind of animal studies are relevant and which aren’t

1:21:03 – What kind of research would you like to see?

Stephan Guyenet Links:

Ketogeek Link:

Citations:

NUSI-Hall Study: https://academic.oup.com/ajcn/article/104/2/324/4564649

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Obesity is a complicated problem and the solution may lie in a multi-prong approach. We look at what the science tells us about obesity, how various properties of foods can impact consumption, discuss the Carbohydrate Insulin Hypothesis and understand how the brain and body responds to an obesogenic environment.

Bio:

Stephan J. Guyenet, PhD is a former neuroscience and obesity researcher and author of the book The Hungry Brain: Outsmarting the Instincts That Make Us Overeat, which was named one of the best books of 2017 by Publishers Weekly. His research has been cited more than 2,000 times by his scientific peers. His writing and speaking focus on the brain circuits that regulate eating behavior and body fatness, and how we can work with them to sustainably manage our waistlines.

Time Stamps:

12:45 – Stephan’s journey into neuroscience and obesity research

16:06 – What caused obesity in humans?

20:22 – The connection between smoking and obesity?

22:32 – Why does every new diet trend such as paleo fail to reverse obesity crisis?

30:31 – Why focusing purely on taste and flavor to gauge food could be obesogenic.

36:36 – Why pure sugar, pure fat and pure sugar/fat are difficult to consume but in the right combination can be addictive and be overconsumed?

45:49 – How sensory variety could lead to overconsumption

48:40 – NUSI study and why Carbohydrate Insulin Hypothesis probably isn’t the sole driver of obesity

59:39 – Can eating fat raise insulin over time?

1:04:04 – How the food industry is incentivized to create obesogenic foods

1:08:11 – What drives cravings?

1:10:45 – Is short term overconsumption a good predictor of long term overconsumption?

1:14:04 – Does sugar addiction exist?

1:17:20 – Understanding what kind of animal studies are relevant and which aren’t

1:21:03 – What kind of research would you like to see?

Stephan Guyenet Links:

Ketogeek Link:

Citations:

NUSI-Hall Study: https://academic.oup.com/ajcn/article/104/2/324/4564649

Previous Episode

undefined - 42. Viability of a Plant-Based Keto Diet & Patient Centered Medicine | Carrie Diulus MD

42. Viability of a Plant-Based Keto Diet & Patient Centered Medicine | Carrie Diulus MD

This is a VERY loaded podcast in which we talk about combining minimally invasive surgical and medical care with nutrition to Carrie's journey with Type 1 Diabetes and her decision to pursue a plant-based ketogenic diet and then discuss the viability of plant based diets when it comes to achieving dietary and therapeutic goals.

Bio: Dr. Carrie Diulus is one of just a handful of board certified female orthopedic spine surgeons in the United States. She practices “patient-centered” medicine rather than the traditional “disease-centered” model. She starts by identifying all of the factors that influence a patient’s health. This understanding is then combined with state-of-the-art minimally invasive surgical and medical care including complementary and nutritional approaches to develop an individualized program for each patient’s unique needs.

S̶h̶e̶ ̶p̶o̶s̶s̶e̶s̶s̶e̶s̶ ̶s̶u̶p̶e̶r̶h̶u̶m̶a̶n̶ ̶s̶t̶r̶e̶n̶g̶t̶h̶,̶ ̶e̶n̶d̶u̶r̶a̶n̶c̶e̶,̶ ̶s̶t̶a̶m̶i̶n̶a̶,̶ ̶f̶l̶i̶g̶h̶t̶ ̶u̶p̶ ̶t̶o̶ ̶s̶i̶x̶ ̶t̶i̶m̶e̶s̶ ̶t̶h̶e̶ ̶s̶p̶e̶e̶d̶ ̶o̶f̶ ̶s̶o̶u̶n̶d̶,̶ ̶p̶h̶y̶s̶i̶c̶a̶l̶ ̶d̶u̶r̶a̶b̶i̶l̶i̶t̶y̶,̶ ̶a̶ ̶s̶i̶x̶t̶h̶ ̶s̶e̶n̶s̶e̶ ̶a̶n̶d̶ ̶i̶s̶ ̶r̶e̶s̶i̶s̶t̶a̶n̶t̶ ̶t̶o̶ ̶m̶o̶s̶t̶ ̶t̶o̶x̶i̶n̶s̶ ̶a̶n̶d̶ ̶p̶o̶i̶s̶o̶n̶s̶.̶ ̶I̶n̶ ̶h̶e̶r̶ ̶B̶i̶n̶a̶r̶y̶ ̶f̶o̶r̶m̶,̶ ̶s̶h̶e̶ ̶c̶a̶n̶ ̶a̶b̶s̶o̶r̶b̶ ̶e̶n̶e̶r̶g̶y̶ ̶a̶n̶d̶ ̶f̶i̶r̶e̶ ̶p̶h̶o̶t̶o̶n̶i̶c̶ ̶p̶r̶o̶j̶e̶c̶t̶i̶l̶e̶s̶ ̶w̶h̶i̶l̶e̶ ̶b̶e̶i̶n̶g̶ ̶a̶b̶l̶e̶ ̶t̶o̶ ̶s̶u̶r̶v̶i̶v̶e̶ ̶t̶h̶e̶ ̶v̶a̶c̶u̶u̶m̶ ̶o̶f̶ ̶s̶p̶a̶c̶e̶.̶

Time Stamps:

0:16 – “Energy Pod Wars”

7:22 – Why did you become an orthopedic spine surgeon?

10:05 – How do you reduce the invasiveness of a surgery?

13:06 – What does “inflammation” actually mean and its connection with ketosis?

15:52 – Is there a connection between ketogenic diet and wound healing?

17:39 – How do you compose a ketogenic diet for your goals?

21:24 – How do you maintain adherence to a diet?

25:53 – What exactly is insulin resistance in your perspective?

30:17 – How did you become a Type 1 diabetic and your journey with it?

33.55 – Challenges with protein intake and working with plant based proteins

42:23 – Breaking dogma, adaptability and finding solutions that work for an individual

44:35 – Bioavailability of plants and the paradox of “fruitarians”

45:57 – How different dietary components can impact health

51:02 – The importance of stable fatty acids in foods

52:12 - Should I be worried of plant toxins such as lectins and oxalates?

58:04 – What is your workout and physical routines like?

1:05:42 – Vegan Keto vs. Omnivore Keto

1:08:19 – Important things to know before going Vegan Keto

1:10:15 – Concerns with many of the Keto food products

Guest Links:

Ketogeek Links:

Next Episode

undefined - 44. Using a Fruit-Based Fruitarian Diet to Perform High Level Ultra-Endurance Sports | Michael Arnstein

44. Using a Fruit-Based Fruitarian Diet to Perform High Level Ultra-Endurance Sports | Michael Arnstein

What happens when you eat nothing but fruits? In this episode, we talk to Michael Arnstein or "The Fruitarian" who has utilized a fruit-based diet for 10 years to perform world class marathon runs and endurance sports and try to understand how this is even possible?

Bio:

Michael Arnstein is a 41 year old elite athlete who lives in New York and Hawaii and utilizes a fruit-based diet to boost his performance. He is also the founder of Woodstock Fruit Festival in 2011. His performance records include:

Marathons (run 100+ marathons, best 2:28.12 NYC) Ironman Triathlons (4 time Kona Hawaii Ironman finisher, best 9:38) Ultra Running (50+ ultra distance races, many major event 1st place finishes) Some highlight performances: 2 time HURT 100 mile winner Vermont 100 mile winner Javelina 100 mile winner 100 mile PR: 12:57 (track; 7:46 per mile average) JFK 50 2nd place 5 hours 50 minutes Badwater 135 finisher Spartathlon 153 mile finisher Time Stamps:

10:10 – How did you get into a fruitarian diet?

17:34 – How do you foster a positive attitude in life?

18:36 – What resources did you use to learn this lifestyle?

21:46 – How do you transition into a fruitarian diet?

25:13 – Is Vitamin B12 deficiency or supplemenation an issue on this diet?

27:50 – What about protein deficiency on this diet?

31:44 – Is there potential science around a fruit based diet?

34:17 – How do you prepare for race day?

36:38 – No drinking water on this diet!?

39:14 – What mangoes are the best in the world?

40:23 – Favorite fruits and fruits you avoid?

43:23 – Salt and do you crave salty foods?

45:09 – What about electrolytes and caffeine?

47:36 – How does the race day fair on a fruitarian diet?

49:09 – What does your physician say about your diet?

50:40 – Are there other athletes who are on a raw fruit diet?

52:07 – Can you make this diet more sustainable?

56:36 – How did this diet impact your social life and relationships?

1:02:00 – Discussion about suffering and compassion

Mike Arnstein Links:

Ketogeek Link:

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