
861 - How to BEST Navigate a Herxheimer Reaction (Die-Off)
11/15/23 • 19 min
A Herxheimer reaction (aka die-off) is essentially when a new protocol makes you feel worse before you start to feel better.
This often gets confused with intolerance, which makes sense when gauging how a new protocol makes you feel. But to make sure you aren’t jumping ship on a protocol that may actually be working for you, it’s important to learn how to recognize the difference between die-off and intolerance.
Join me to learn how to best navigate Herxheimer symptoms and what you can do to manage them.
Featured Studies- https://pubmed.ncbi.nlm.nih.gov/32491752/#:~:text=It%20usually%20manifests%20as%20fever,and%20exacerbation%20of%20skin%20lesions.
- https://pubmed.ncbi.nlm.nih.gov/23632012/
- https://pubmed.ncbi.nlm.nih.gov/28078798/
- https://pubmed.ncbi.nlm.nih.gov/21381407/
- https://pubmed.ncbi.nlm.nih.gov/29508268/
- https://pubmed.ncbi.nlm.nih.gov/29460487/
- https://pubmed.ncbi.nlm.nih.gov/24891990/
- https://pubmed.ncbi.nlm.nih.gov/32020750/
- https://pubmed.ncbi.nlm.nih.gov/29493919/
- https://pubmed.ncbi.nlm.nih.gov/31935866/
- https://pubmed.ncbi.nlm.nih.gov/33380301/
- https://pubmed.ncbi.nlm.nih.gov/31680558/
- https://pubmed.ncbi.nlm.nih.gov/35094209/
- https://pubmed.ncbi.nlm.nih.gov/29763052/#:~:text=Vitamin%20C%20is%20a%20water,intake%20of%20fruits%20and%20vegetables.
- Probiotic Side Effects & How to Fix Them: https://www.youtube.com/watch?v=mbHCR6esOuY
- My articles: https://drruscio.com/blog/
- My book: https://drruscio.com/getgutbook/
- Courses, free guides, and more: https://drruscio.com/resources?utm_source=youtube&utm_medium=link&utm_campaign=drruscio.com_resources
00:00 Intro
02:37 Symptoms of die off
03:34 The prevalence of die off
05:32 How to distinguish die off from intolerance
08:16 The protocol
11:25 Other die off supports
14:46 Antimicrobial die off
Get the Latest UpdatesFacebook - https://www.facebook.com/DrRusciodc
Instagram - https://www.instagram.com/drrusciodc/
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DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.
Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g
*Full transcript available on YouTube by clicking the “Show transcript” button on the bottom right of the video.
A Herxheimer reaction (aka die-off) is essentially when a new protocol makes you feel worse before you start to feel better.
This often gets confused with intolerance, which makes sense when gauging how a new protocol makes you feel. But to make sure you aren’t jumping ship on a protocol that may actually be working for you, it’s important to learn how to recognize the difference between die-off and intolerance.
Join me to learn how to best navigate Herxheimer symptoms and what you can do to manage them.
Featured Studies- https://pubmed.ncbi.nlm.nih.gov/32491752/#:~:text=It%20usually%20manifests%20as%20fever,and%20exacerbation%20of%20skin%20lesions.
- https://pubmed.ncbi.nlm.nih.gov/23632012/
- https://pubmed.ncbi.nlm.nih.gov/28078798/
- https://pubmed.ncbi.nlm.nih.gov/21381407/
- https://pubmed.ncbi.nlm.nih.gov/29508268/
- https://pubmed.ncbi.nlm.nih.gov/29460487/
- https://pubmed.ncbi.nlm.nih.gov/24891990/
- https://pubmed.ncbi.nlm.nih.gov/32020750/
- https://pubmed.ncbi.nlm.nih.gov/29493919/
- https://pubmed.ncbi.nlm.nih.gov/31935866/
- https://pubmed.ncbi.nlm.nih.gov/33380301/
- https://pubmed.ncbi.nlm.nih.gov/31680558/
- https://pubmed.ncbi.nlm.nih.gov/35094209/
- https://pubmed.ncbi.nlm.nih.gov/29763052/#:~:text=Vitamin%20C%20is%20a%20water,intake%20of%20fruits%20and%20vegetables.
- Probiotic Side Effects & How to Fix Them: https://www.youtube.com/watch?v=mbHCR6esOuY
- My articles: https://drruscio.com/blog/
- My book: https://drruscio.com/getgutbook/
- Courses, free guides, and more: https://drruscio.com/resources?utm_source=youtube&utm_medium=link&utm_campaign=drruscio.com_resources
00:00 Intro
02:37 Symptoms of die off
03:34 The prevalence of die off
05:32 How to distinguish die off from intolerance
08:16 The protocol
11:25 Other die off supports
14:46 Antimicrobial die off
Get the Latest UpdatesFacebook - https://www.facebook.com/DrRusciodc
Instagram - https://www.instagram.com/drrusciodc/
Pinterest - https://www.pinterest.ca/drmichaelrusciodc
DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.
Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g
*Full transcript available on YouTube by clicking the “Show transcript” button on the bottom right of the video.
Previous Episode

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Featured Studies- https://pubmed.ncbi.nlm.nih.gov/35129111/
- https://pubmed.ncbi.nlm.nih.gov/37150125/
- https://pubmed.ncbi.nlm.nih.gov/37049546/
- https://pubmed.ncbi.nlm.nih.gov/36717369/
- https://pubmed.ncbi.nlm.nih.gov/37116031/
- https://pubmed.ncbi.nlm.nih.gov/36757002/
- https://pubmed.ncbi.nlm.nih.gov/37256113/
- https://pubmed.ncbi.nlm.nih.gov/37105767/
- https://pubmed.ncbi.nlm.nih.gov/36974511/
- My articles: https://drruscio.com/blog/
- My book: https://drruscio.com/getgutbook/
- Courses, free guides, and more: https://drruscio.com/resources?utm_source=youtube&utm_medium=link&utm_campaign=drruscio.com_resources
00:00 Intro
02:01 Our probiotic protocol
02:58 Do probiotics improve depression?
07: 11 A combination of probiotics & lifestyle changes
08:30 Parkinson’s disease
09:58 How the gut and brain connect
11:31 A new brain health finding
13:45 Probiotic protocol recap
14:29 No studies for bloating?
19:06 Can probiotics can improve diarrhea?
19:27 What if you stop probiotics too soon?
22:33 Soil-based probiotics for constipation in kids
23:45 Is there a best probiotic for h. pylori?
Get the Latest UpdatesFacebook - https://www.facebook.com/DrRusciodc
Instagram - https://www.instagram.com/drrusciodc/
Pinterest - https://www.pinterest.ca/drmichaelrusciodc
DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.
Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g
*Full transcript available on YouTube by clicking the “Show transcript” button on the bottom right of the video.
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Featured Studies- https://pubmed.ncbi.nlm.nih.gov/35999903/
- https://pubmed.ncbi.nlm.nih.gov/36079838/
- https://pubmed.ncbi.nlm.nih.gov/35743024/
- https://pubmed.ncbi.nlm.nih.gov/11836274/
- https://pubmed.ncbi.nlm.nih.gov/760358/
- https://pubmed.ncbi.nlm.nih.gov/14558922/
- https://pubmed.ncbi.nlm.nih.gov/10779140/#:~:text=Ultrasonography%20(US)%20may%20demonstrate%20a,from%2019%25%20to%2095%25.
- https://pubmed.ncbi.nlm.nih.gov/18324487/
- https://academic.oup.com/jcem/article/84/2/561/2864306
- https://pubmed.ncbi.nlm.nih.gov/28052092/
- https://pubmed.ncbi.nlm.nih.gov/32805423/
- https://pubmed.ncbi.nlm.nih.gov/20361146/#:~:text=Background%3A%20Anti%2Dthyroid%20peroxidase%20antibodies,positive%20titers%20of%20these%20antibodies.
- https://pubmed.ncbi.nlm.nih.gov/30078965/
- https://pubmed.ncbi.nlm.nih.gov/37489370/
- https://pubmed.ncbi.nlm.nih.gov/35243857/
- https://pubmed.ncbi.nlm.nih.gov/27607246/
- https://pubmed.ncbi.nlm.nih.gov/30215224/
- https://pubmed.ncbi.nlm.nih.gov/28536577/
- https://pubmed.ncbi.nlm.nih.gov/24154902/
- https://pubmed.ncbi.nlm.nih.gov/34766382/
- https://pubmed.ncbi.nlm.nih.gov/32588591/
- https://pubmed.ncbi.nlm.nih.gov/36598468/#:~:text=The%20Paleo%20diet%20has%20been,shown%20positive%20results%20on%20AITD.
- https://pubmed.ncbi.nlm.nih.gov/31275780/
- https://pubmed.ncbi.nlm.nih.gov/24885375/
- https://pubmed.ncbi.nlm.nih.gov/35565695/
- https://pubmed.ncbi.nlm.nih.gov/37554764/
- https://pubmed.ncbi.nlm.nih.gov/28255299/
- https://pubmed.ncbi.nlm.nih.gov/24224112/
- https://pubmed.ncbi.nlm.nih.gov/33679732/
- https://pubmed.ncbi.nlm.nih.gov/34871506/
- https://pubmed.ncbi.nlm.nih.gov/34981556/
- https://pubmed.ncbi.nlm.nih.gov/30285179/
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- Our Study: https://pubmed.ncbi.nlm.nih.gov/36079838/
- My articles: https://drruscio.com/blog/
- My book: https://drruscio.com/getgutbo...
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