
How Do You Solve a Problem Like Big Pharma? We Ask a Bioethicist
Explicit content warning
03/13/25 • 71 min
"Big Pharma" — two words that Americans love to hate. When asked about the pharmaceutical industry, most of the country responds with a mix of anger and suspicion, using terms like "corporate capture," "revolving door," and "profits over people" to describe its influence, a sentiment felt even stronger after the pandemic. And yet, we are a nation that depends on their life-saving, life-improving products. Americans demand innovation from Big Pharma, but are simultaneously frustrated and mistrustful of their motives and influence. Today, we delve into our complex relationship with the pharmaceutical industry. What fuels this mistrust? Is there a better system? Joining us is bioethicist, author, and TED Talk star hailing from Penn State University Jonathan Marks, who believes it doesn’t have to be this way.
Hosts:
Brinda Adhikari
Tom Johnson
Maggie Bartlett
Dr. Mark Abdelmalek
Guest:
Jonathan Marks, Director of Bioethics Program at Penn State University, lawyer, author The Perils of Partnership: Industry Influence, Institutional Integrity, and Public Health
Sources:
2019 pharma ranked least well regarded industry
https://news.gallup.com/poll/266060/big-pharma-sinks-bottom-industry-rankings.aspx
2023 Gallup on pharma
https://news.gallup.com/poll/510641/retail-pharmaceutical-industries-slip-public-esteem.aspx
Lessons from Corporate Influence in the Opioid Epidemic https://pubmed.ncbi.nlm.nih.gov/32661741/
STAT on financial donations to Congress
https://www.statnews.com/feature/prescription-politics/federal-full-data-set/
NIH funds drug research
https://pmc.ncbi.nlm.nih.gov/articles/PMC5878010/
TED TALK: Jonathan Marks: In Praise of Conflict
https://www.youtube.com/watch?v=Sf8j5LFv3nI
Thanks for listening! If you like us, please leave a review, rate us, and please subscribe!
Got questions? Comments? We'd love to hear from you! Email us at [email protected]
"Big Pharma" — two words that Americans love to hate. When asked about the pharmaceutical industry, most of the country responds with a mix of anger and suspicion, using terms like "corporate capture," "revolving door," and "profits over people" to describe its influence, a sentiment felt even stronger after the pandemic. And yet, we are a nation that depends on their life-saving, life-improving products. Americans demand innovation from Big Pharma, but are simultaneously frustrated and mistrustful of their motives and influence. Today, we delve into our complex relationship with the pharmaceutical industry. What fuels this mistrust? Is there a better system? Joining us is bioethicist, author, and TED Talk star hailing from Penn State University Jonathan Marks, who believes it doesn’t have to be this way.
Hosts:
Brinda Adhikari
Tom Johnson
Maggie Bartlett
Dr. Mark Abdelmalek
Guest:
Jonathan Marks, Director of Bioethics Program at Penn State University, lawyer, author The Perils of Partnership: Industry Influence, Institutional Integrity, and Public Health
Sources:
2019 pharma ranked least well regarded industry
https://news.gallup.com/poll/266060/big-pharma-sinks-bottom-industry-rankings.aspx
2023 Gallup on pharma
https://news.gallup.com/poll/510641/retail-pharmaceutical-industries-slip-public-esteem.aspx
Lessons from Corporate Influence in the Opioid Epidemic https://pubmed.ncbi.nlm.nih.gov/32661741/
STAT on financial donations to Congress
https://www.statnews.com/feature/prescription-politics/federal-full-data-set/
NIH funds drug research
https://pmc.ncbi.nlm.nih.gov/articles/PMC5878010/
TED TALK: Jonathan Marks: In Praise of Conflict
https://www.youtube.com/watch?v=Sf8j5LFv3nI
Thanks for listening! If you like us, please leave a review, rate us, and please subscribe!
Got questions? Comments? We'd love to hear from you! Email us at [email protected]
Previous Episode

Censorship vs. Science: The Fight Over Free Speech That Is Tearing Us Apart
During incoming NIH secretary Dr. Jay Bhattacharya's confirmation hearing this week, he vowed to "establish a culture of respect for free speech in science & scientific dissent at the NIH"; he went on to call dissent "the very essence of science". Dr. Bhattacharya has been one of the most outspoken critics of what he perceives to be censorship and the deliberate muzzling of scientists during Covid.
Today, we dive into the complex and contentious issue of censorship—one of the biggest drivers of mistrust in public health. Was it justified for the government to pressure social media companies to remove posts about COVID-19 and vaccines that they deemed dangerous misinformation? Or did that cross a line into stifling free speech?
today, with the Trump administration now overseeing public health, issuing new executive orders aimed at limiting DEI programs, language and studies throughout the federal government.
Do these actions cross the line into censoring science? Why are we caught in a battle between science and free speech, and how did we get here? And how do we move forward?
To help explore these questions, we’re joined by two individuals from very different backgrounds who emerged as important voices during the pandemic: Wilk Wilkinson, a trucking company manager in Central Minnesota and host of the Derate The Hate podcast who has joined forces with scientists such as Dr Francis Collins and Dr Jay Bhattacharya on various topics; and Dr. Maciej Boni, a biology professor at Temple University and infectious disease epidemiologist who worked on the front lines of various outbreaks, from swine flu, bird flu to Covid-19.
Hosts:
Brinda Adhikari
Tom Johnson
Maggie Bartlett
Dr. Mark Abdelmalek
Guests:
Wilk Wilkinson, Braver Angels leader; Host of Derate the Hate podcast; manager of trucking operations
Dr. Maciej Boni, professor of biology at Temple University; infectious disease epidemiologist
Sources:
Mark Zuckerberg’s letter to Rep. Jim Jordan
https://www.americanrhetoric.com/speeches/PDFFiles/Mark-Zuckerberg-Letter-on-Govt-Censorship.pdf
Rep. Jim Jordan’s investigation into Biden’s “Censorship Scheme”
Free speech and content moderation
Supreme Court: Murthy v. Missouri
https://hms.harvard.edu/news/whats-stake-us-supreme-court-case-misinformation
Supreme Court: Missouri v. Biden
Biden & Social Media
https://www.nytimes.com/2021/07/16/us/politics/biden-facebook-social-media-covid.html
Thanks for listening! If you like us, please leave a review, rate us, and please subscribe!
Got questions? Comments? We'd love to hear from you! Email us at [email protected]
Next Episode

On Measles: Vaccines vs Vitamin A. Plus, What Marion Nestle Says Public Health Is Getting Wrong
Amid a deadly measles outbreak, a fresh battle has erupted, pitting mainstream public health against MAHA, infectious disease against chronic disease, and Vitamin A against vaccination. It's a fight that hinges on a fundamental question: Is your illness driven more by infectious disease or underlying chronic conditions? One side argues that vaccination is the only way to prevent measles. At the same time, the other emphasizes diet, nutrition, and Vitamin A, even bringing up cod liver oil as part of the discussion. Then there's MAHA's passion to address America’s unhealthy diet. Should critics of MAHA separate what they agree with from what they don't? In this episode, we unpack the fight amid an outbreak and hear from Marion Nestle, one of America’s leading nutritionists and public health experts.
Sources:
Vitamin A and Measles
https://pmc.ncbi.nlm.nih.gov/articles/PMC7076287/
Vitamin A deficiency
https://www.sciencedirect.com/science/article/pii/S0022316622012238?via%3Dihub
RFK Jr on Foxnews:
https://www.foxnews.com/video/6369595673112
RFK Jr with Sean Hannity
https://www.foxnews.com/video/6369888081112
Interview of parents of child in TX measles outbreak death
https://live.childrenshealthdefense.org/chd-tv/shows/good-morning-chd/breaking-news-parents-of-child-in-texas-measles-outbreak-death/
Thanks for listening! If you like us, please leave a review, rate us, and please subscribe!
Got questions? Comments? We'd love to hear from you! Email us at [email protected]
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