#286 - đź“‘ Journal Club - The Complete Episode from march 2nd 2025
03/02/25 • 88 min
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In this episode of The Incubator’s Journal Club, hosts Ben and Daphna open with exciting announcements, including details on the upcoming Delphi Neonatal Innovation Conference and new video content for their “Beyond the Beeps” series on YouTube. They also share updates on the Board Review Podcast, geared toward both board preparation and ongoing learning in neonatology.
The team’s first paper discussion highlights the ECLA trial from The Lancet, which examines higher versus lower CPAP levels for extubating extremely preterm infants. Ben and Daphna explore how higher CPAP may decrease extubation failure and the implications for clinical practice. Next, they review a large population-based study on intraventricular hemorrhage (IVH), underscoring the persistently high rates of IVH in very preterm infants and emphasizing its impact on neurodevelopmental outcomes.
They then welcome guest speaker Dr. Tim Barr from the University of Utah, who introduces the concept of end-tidal carbon monoxide monitoring as a noninvasive tool for detecting hemolysis and guiding bilirubin management. Dr. Barr explains how this method may help clinicians identify and treat high-risk neonates earlier. The discussion closes with a look at recent data on early hydrocortisone use in neonatal shock and a paper examining discrepancies between parental and medical classifications of neurodevelopmental impairment. Through in-depth research reviews and expert commentary, this episode showcases The Incubator’s commitment to advancing neonatal care.
As always, feel free to send us questions, comments, or suggestions to our email: [email protected]. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.
Enjoy!
In this episode of The Incubator’s Journal Club, hosts Ben and Daphna open with exciting announcements, including details on the upcoming Delphi Neonatal Innovation Conference and new video content for their “Beyond the Beeps” series on YouTube. They also share updates on the Board Review Podcast, geared toward both board preparation and ongoing learning in neonatology.
The team’s first paper discussion highlights the ECLA trial from The Lancet, which examines higher versus lower CPAP levels for extubating extremely preterm infants. Ben and Daphna explore how higher CPAP may decrease extubation failure and the implications for clinical practice. Next, they review a large population-based study on intraventricular hemorrhage (IVH), underscoring the persistently high rates of IVH in very preterm infants and emphasizing its impact on neurodevelopmental outcomes.
They then welcome guest speaker Dr. Tim Barr from the University of Utah, who introduces the concept of end-tidal carbon monoxide monitoring as a noninvasive tool for detecting hemolysis and guiding bilirubin management. Dr. Barr explains how this method may help clinicians identify and treat high-risk neonates earlier. The discussion closes with a look at recent data on early hydrocortisone use in neonatal shock and a paper examining discrepancies between parental and medical classifications of neurodevelopmental impairment. Through in-depth research reviews and expert commentary, this episode showcases The Incubator’s commitment to advancing neonatal care.
As always, feel free to send us questions, comments, or suggestions to our email: [email protected]. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.
Enjoy!
Previous Episode
#286 - [Journal Club Shorts] - đź“Ś Parental and Medical Classification of Neurodevelopment in Children Born Preterm.
Parental and Medical Classification of Neurodevelopment in Children Born Preterm.
Richter LL, Janvier A, Pearce R, Bourque CJ, Church PT, Luu TM, Synnes A.Pediatrics. 2025 Feb 1;155(2):e2024066148. doi: 10.1542/peds.2024-066148.PMID: 39786567
As always, feel free to send us questions, comments, or suggestions to our email: [email protected]. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.
Enjoy!
Next Episode
#287 - 🚀 End-Tidal Carbon Monoxide Monitoring for the Management of Neonatal Jaundice
In this special Tech Tuesday episode of The Incubator Podcast, Ben and Daphna sit down with Anthony Wu, CEO of Capnia, Inc., to explore how end-tidal carbon monoxide (ETCO) monitoring is impacting neonatal jaundice management. Anthony explains how this technology, based on decades of research, provides a real-time, non-invasive biomarker for hemolysis and thus indirectly, bilirubin production, allowing clinicians to better assess and predict neonatal jaundice severity. Unlike traditional serum bilirubin tests, which only measure bilirubin levels at a given time, ETCO screening gives insight into hemolysis rates, helping identify newborns at risk for severe jaundice before complications arise.
Anthony shares his personal motivation behind this innovation, discussing how his own children experienced neonatal jaundice and how many families suffer the emotional and financial burden of this pathology. He envisions a future where universal ETCO screening becomes standard practice, allowing for earlier interventions and reducing the risk of preventable neurological damage.
Tune in for an eye-opening discussion on how this innovation could change the way we approach neonatal jaundice forever!
As always, feel free to send us questions, comments, or suggestions to our email: [email protected]. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.
Enjoy!
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