PREVIEW Aliquot #25: Coffee, caffeine, and sleep

04/01/21 • 25 min

Coffee consumption is associated with protection from several chronic diseases, including cancer, cardiovascular disease, and neurodegenerative disease. Whereas some of the beneficial effects of coffee may stem from its ability to induce autophagy, other evidence points to the benefits of caffeine, which, when consumed early in the morning – resets the body's internal clocks and provides a mental boost that helps us start the day and may even protect telomeres. But the long half-life of caffeine can reduce sleep quality, fueling a vicious cycle of poor sleep, daytime grogginess, and increased caffeine consumption. This Aliquot segment features Dr. Guido Kroemer, an expert in immunology, cancer biology, aging, and autophagy; Dr. Satchin Panda, an expert in circadian rhythm research; Dr. Matthew Walker, a professor of neuroscience and psychology; Dr. Elissa Epel, an expert in telomere biology; and Dr. Rhonda Patrick (in an interview with Mike Maser).

(00:00) Introduction
(02:13) The class of compounds known as “caloric restriction mimetics” that affect autophagy (Guido Kroemer discussion)
(11:04) Time-restricted feeding and coffee (Satchin Panda discussion)
(18:06) The impact of diet on telomere length (Elissa Epel discussion)
(19:31) Coffee in the evening reduces deep sleep by about 20 percent (Matthew Walker discussion)
(21:58) The autophagy-enhancing effect of coffee (Guido Kroemer discussion)
(23:41) Amount of caffeine in breastmilk (Rhonda Patrick discussion)

You can see the original full interview with Dr. Kroemer You can see the original full interview with Dr. Panda You can hear the original full interview with Dr. Rhonda Patrick and Mike Maser You can see the original full interview with Dr. Epel You can see the original full interview with Dr. Walker

Get more Aliquots! Become a FMF Premium member and get full access to our members-only podcast, The Aliquot, plus live Q&As with Rhonda, biweekly Science Digest emails, and more.

Learn more and sign up at: www.foundmyfitness.com/crowdsponsor

(00:00) Introduction
(02:13) The class of compounds known as “caloric restriction mimetics” that affect autophagy (Guido Kroemer discussion)
(11:04) Time-restricted feeding and coffee (Satchin Panda discussion)
(18:06) The impact of diet on telomere length (Elissa Epel discussion)
(19:31) Coffee in the evening reduces deep sleep by about 20 percent (Matthew Walker discussion)
(21:58) The autophagy-enhancing effect of coffee (Guido Kroemer discussion)
(23:41) Amount of caffeine in breastmilk (Rhonda Patrick discussion)

Get more Aliquots! Become a FMF Premium member and get full access to our members-only podcast, The Aliquot, plus live Q&As with Rhonda, biweekly Science Digest emails, and more.

Learn more and sign up at: www.foundmyfitness.com/crowdsponsor

Previous Episode

PREVIEW Aliquot #22: Q&A Mashup - Rhonda's personal supplement routine

This month’s Aliquot Preview episode is a special mashup episode features a compilation of supplement-related topics taken from many of my Q&A episodes over the last couple of years.

This episode covers many supplement-related topics including:

(00:00) Introduction
(00:49) Personal supplementation routine as of October 2017
(08:04) Personal supplementation routine as of May 2019
(08:33) Personal supplementation routine as of December 2019
(10:39) Why I currently do not take NR or NMN.
(13:59) Thoughts on moringa powder in my diet
(17:22) Personal supplementation routine during the COVID-19 pandemic
(28:30) Moringa dose, taste, and possible overlap with prostaphane supplements
(34:27) Why I removed certain ingredients from her smoothie protocol
(36:29) How much vitamin D is necessary to sustain high levels of vitamin D
(37:43) Personal probiotic regimen
(38:49) Does moringa powder lower blood glucose levels?
(40:52) Personal supplementation routine as of February 2021

Please note that the information in this episode is based on Rhonda's own personal experience and is not medical, professional, or licensed advice. If you are thinking about starting or changing your own supplement routine, please make sure you consult your physician or health care provider. Get more Aliquots! Become a FMF Premium member and get full access to our members-only podcast, The Aliquot, plus live Q&As with Rhonda, biweekly Science Digest emails, and more. Learn more and sign up at: www.foundmyfitness.com/crowdsponsor

Next Episode

PREVIEW Aliquot #26: How mRNA COVID-19 Vaccines Work

Traditional vaccines take many years to develop. A recent innovation in vaccine technology involves exploitation of messenger RNA, or mRNA, to facilitate rapid scaling of vaccines and expedite their modification if the virus mutates significantly. The Pfizer and Moderna COVID-19 vaccines capitalize on this technology to induce antibody production against the SARS-CoV-2 virus. In this episode, we discuss:

(00:00) Introduction
(01:31) The difference between the mRNA and traditional vaccines
(06:29) Real vaccine side effects known to exist (and why Dr. Seheult believes that the benefits outweigh the risk)

This Aliquot segment features Dr. Roger Seheult, a quadruple board-certified physician serving on the front lines of COVID-19 care and co-founder of MedCram. You can see the original full interview with Dr. Seheult Get more Aliquots! Become a FMF Premium member and get full access to our members-only podcast, The Aliquot, plus live Q&As with Rhonda, biweekly Science Digest emails, and more. Learn more and sign up at: www.foundmyfitness.com/crowdsponsor