Ep. 63 The Brain's Bouncer: The Blood Brain Barrier
09/21/20 • 57 min
1 Listener
We did a twitter poll and the people have spoken! You folks want to hear about the "Blood Brain Barrier"! But what is it, besides great alliteration?! The blood brain barrier is a lot like a bouncer for the exclusive dance club that is your brain -- but who is allowed in? How does one get in? And on a cellular and protein level, who are the actual bouncers that keep us out? Next week we will get into some of the details on diseases and drugs and their impact on the blood brain barrier, so tune in next week too!
This episode has a promo for Everything I Learned From Movies Podcast! This is a movie and beer discussion podcast! Check them out at @eilfmovies on twitter!
Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast.
References:
- https://www.tandfonline.com/doi/pdf/10.3109/13813452109146211
- https://onlinelibrary.wiley.com/doi/full/10.1002/glia.20642
- https://nyaspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1749-6632.1986.tb27136.x
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267212/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664562/
- https://pubmed.ncbi.nlm.nih.gov/11282155/
- https://www.nature.com/articles/s41598-018-37367-z
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697631/
- https://pubmed.ncbi.nlm.nih.gov/15717053/
- https://www.nature.com/articles/s41366-018-0221-z
- https://www.nature.com/articles/1301452
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796930/
- https://www.ncbi.nlm.nih.gov/books/NBK27998/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494002/
- https://www.frontiersin.org/articles/10.3389/fonc.2018.00239/full
- https://pubmed.ncbi.nlm.nih.gov/20093161/
- https://www.ncbi.nlm.nih.gov/books/NBK53086/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292164/
- https://www.sciencedirect.com/science/article/pii/S0301008215300691
We did a twitter poll and the people have spoken! You folks want to hear about the "Blood Brain Barrier"! But what is it, besides great alliteration?! The blood brain barrier is a lot like a bouncer for the exclusive dance club that is your brain -- but who is allowed in? How does one get in? And on a cellular and protein level, who are the actual bouncers that keep us out? Next week we will get into some of the details on diseases and drugs and their impact on the blood brain barrier, so tune in next week too!
This episode has a promo for Everything I Learned From Movies Podcast! This is a movie and beer discussion podcast! Check them out at @eilfmovies on twitter!
Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast.
References:
- https://www.tandfonline.com/doi/pdf/10.3109/13813452109146211
- https://onlinelibrary.wiley.com/doi/full/10.1002/glia.20642
- https://nyaspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1749-6632.1986.tb27136.x
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267212/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664562/
- https://pubmed.ncbi.nlm.nih.gov/11282155/
- https://www.nature.com/articles/s41598-018-37367-z
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697631/
- https://pubmed.ncbi.nlm.nih.gov/15717053/
- https://www.nature.com/articles/s41366-018-0221-z
- https://www.nature.com/articles/1301452
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796930/
- https://www.ncbi.nlm.nih.gov/books/NBK27998/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494002/
- https://www.frontiersin.org/articles/10.3389/fonc.2018.00239/full
- https://pubmed.ncbi.nlm.nih.gov/20093161/
- https://www.ncbi.nlm.nih.gov/books/NBK53086/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292164/
- https://www.sciencedirect.com/science/article/pii/S0301008215300691
Previous Episode
Ep. 62 Bleedin' Gums and Vitamin C
We all know *about* vitamin C but... what actually IS vitamin C? And what does it even do in your body? How can being deficient in vitamin C make pirates bleed out of their gums and have their teeth fall out? Also, can vitamin C cure cancer? Find out some of this stuff, tune in!
This episode is sponsored in part by Vaer Watches, which you can visit at https://www.vaerwatches.com/. Currently you can get 15% off with the code PODGO15, check it out!
This episode has a promo for Bald Scientist Podcast! This guy is a real legend of a scientist, and he's bringing all sorts of great science and life lessons to your ears! Check him out at https://baldscientist.com/ !
Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast.
References:
- https://apps.who.int/iris/bitstream/handle/10665/42716/9241546123.pdf
- https://www.jstor.org/stable/pdf/20094480.pdf
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145266/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901412
- https://www.ncbi.nlm.nih.gov/books/NBK493187/
- https://www.ncbi.nlm.nih.gov/books/NBK493187/
- https://hekint.org/documents/sailors_scurvy-final.pdf
- https://www.alcademics.com/2018/11/historical-info-about-scurvy-and-the-confusion-between-lemons-and-limes.html
- https://www.mdpi.com/2072-6643/9/4/339
- https://www.mdpi.com/2072-6643/9/11/1211
- https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD000980.pub4/full
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039380/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725835/
- https://jamanetwork.com/journals/jama/fullarticle/2752063
- https://jamanetwork.com/journals/jama/fullarticle/2761631
- https://jamanetwork.com/journals/jama/fullarticle/2769467
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725125/
- https://www.mdpi.com/2072-6643/9/9/960
- https://www.nature.com/articles/s41568-019-0135-7
Next Episode
Ep. 64 The BBB2: The Crack in the Wall
Last episode introduced the blood brain barrier; it is a lot like a bouncer for the exclusive dance club that is your brain, keeping all the randos out. But this week we get into some of the details on diseases and drugs and their impact on the blood brain barrier. Also, sometimes we WANT drugs to get into the brain, so how can we get around this BBB?
This episode has a promo for Lit Gaming Area Podcast! This is a gaming news and discussion podcast! Check them out at @litgamingarena on twitter!
Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast.
References:
- https://www.ahajournals.org/doi/10.1161/01.HYP.2.6.809
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733101/
- https://www.ncbi.nlm.nih.gov/books/NBK554499/
- https://science.sciencemag.org/content/366/6472/1448?rss=1
- https://journals.sagepub.com/doi/full/10.1177/0271678X15616978
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320935/
- https://onlinelibrary.wiley.com/doi/full/10.1002/ana.24271
- https://www.sciencedirect.com/science/article/pii/S014976341730773X
- https://www.nature.com/articles/s41568-019-0205-x
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169949/
- https://www.nih.gov/news-events/nih-research-matters/how-cancer-vesicles-breach-blood-brain-barrier
- https://www.frontiersin.org/articles/10.3389/fneng.2013.00007/full
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751454/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694729/
- https://www.nature.com/articles/d41573-020-00102-3
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337067/
- https://www.nature.com/articles/s41598-019-42272-0
- https://pubmed.ncbi.nlm.nih.gov/17472409/
- https://www.tandfonline.com/doi/full/10.1080/17425247.2018.1429401
- https://www.pnas.org/content/114/1/E75
- https://www.tandfonline.com/doi/full/10.1080/17425247.2020.1698544
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