Ep#043: Developing Precision Medicines Using Cryo-EM with Dr. Sriram Subramaniam

06/16/22 • 43 min

In this episode we dive deep into the world of structural biology. We discuss the role of cryogenic electron microscopy in the development of precision medicines with the founder and CEO of Gandeeva Therapeutics, Dr. Sriram Subramaniam. Cryo-EM opened a new way to study drug-target interactions and is changing the way we develop new therapies.
Tune into our interview with Sriram to learn more about:
◦ The founding story of Gandeeva Therapeutics
◦ The evolution of Cryo-EM technology
◦ Application of Cryo-EM in drug discovery
◦ Advantages of Cryo-EM over crystallography im mapping protein structures
◦ Making sense of experimental data with AI and machine learning
◦ The future of personalized medicine and role of structural biology in it
◦ Sriram’s advice for budding life science entrepreneurs

Previous Episode

Ep#042: Applying Epigenetics to Personalized Skincare with Dr. Shakiba Kaveh and Dr. Cristiana Banila

In this next podcast episode we dive into a topic of personalized skincare. Our host Oleksandr is joined by the co-founders of Mitra Bio, Dr. Shakiba Kaveh and Dr. Cristiana Banila.
Pharmaceutical and personal care companies have been trying to unlock personalized skincare for decades. Shakiba and Cristiana bring a special key to the table, and it is epigenetics.
Tune in into our interview to learn more about:
◦ The founding story of Mitra Bio
◦ The role of genetic and epigenetic factors in skin health
◦ Cracking epigenetic code
◦ Role of reliable models in understanding skin diseases
◦ Skin aging and personalized approaches to reverse it
◦ The future of personalized skincare
◦ Advice to young biotech entrepreneurs from Shakiba and Cristiana

Next Episode

Ep#044: Applying Nanoparticles and Microfluidics to Personalized Medicine with Martin Rabel

Welcome to the next episode of the Personalized Medicine Podcast. In this episode, our host Aradhana talked to Martin Rabel, the Field Application Scientist at Precision Nanosystems, about nanoparticles, microfluidics, gene delivery in the context of personalized medicine.
Tune in to this episode to learn more about:
◦ Precision Nanosystems and their mission
◦ Role of nanoparticles and microfluidics in Personalized Medicine
◦ Next-Gen microfluidics technologies
◦ Application of nanoparticles in pharmaceutical applications
◦ Challenges in developing RNA-based lipid nanoparticles
◦ Role of regulatory bodies in implementation of personalized medicine approaches
◦ The outlook on the future of personalized medicine
Get in touch with Martin:
◦ LinkedIn: Martin Rabel
◦ Twitter: @rabel_martin