PeerView Immunology & Transplantation CME/CNE/CPE Video Podcast - Ghassan Abou-Alfa, MD, MBA - ‘How I Think, How I Treat’—Embarking on a New Treatment Era in Hepatocellular Carcinoma: A Personal Take on Integrating Recent Evidence Into the Continuum of Care for Patients With HCC

Ghassan Abou-Alfa, MD, MBA - ‘How I Think, How I Treat’—Embarking on a New Treatment Era in Hepatocellular Carcinoma: A Personal Take on Integrating Recent Evidence Into the Continuum of Care for Patients With HCC

08/07/19 • 105 min

PeerView Immunology & Transplantation CME/CNE/CPE Video Podcast

Go online to PeerView.com/XEJ860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Multiple new drug approvals and positive clinical trial outcomes have set the stage for the wider integration of novel therapeutics across the treatment spectrum of hepatocellular carcinoma (HCC). These developments have established multiple targeted and immunotherapy agents as options in advanced disease while also mapping potential future applications in intermediate stage HCC and beyond. Future care will depend on the successful integration of newer tyrosine kinase inhibitor (TKI)-based approaches with established and emerging immune checkpoint inhibitors across patient populations and lines of therapy. This PeerView “How I Think, How I Treat” activity, based on a symposium held during the 2019 American Society of Clinical Oncology Annual Meeting in Chicago, offers an inside look at how experts translate important new data and navigate the current HCC landscape in order to provide the most benefit for their patients. This activity also features important insights on how to utilize newly approved TKIs and checkpoint inhibitors across disease and treatment settings, as well as provides expert thoughts on the next wave of emerging solutions that leverage the power of novel therapies across the continuum of HCC. Upon completion of this activity, participants should be better able to: Summarize emerging clinical evidence on the use of novel systemic treatments, including targeted and immunotherapeutic agents, in a range of HCC treatment settings and populations, Apply recent safety and efficacy data on targeted therapies into clinical practice to enhance aspects of HCC care, including treatment sequencing and managing treatment-related adverse events, Integrate immunotherapeutic strategies for the management of patients with advanced HCC, including through optimal treatment selection and via management of immune-related adverse events, Identify innovative treatment strategies currently being assessed in clinical trials across the spectrum of HCC, such as immunotherapy combinations, combinations of novel agents with locoregional therapies, and early transition to systemic treatment, among others.

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Michael E. Wechsler, MD - Advances in the Treatment of Uncontrolled Persistent Asthma: Expert Insights in Personalizing Patient Care

Go online to PeerView.com/PBN860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, experts in asthma discuss recent advances in the treatment of uncontrolled persistent asthma and offer practical guidance on personalizing patient care. Upon completion of this activity, participants should be better able to: Describe the mechanisms of inflammatory pathways in uncontrolled persistent asthma and their implications for treatment, Assess patients with asthma for symptom severity, disease phenotypes, exacerbation risk, and eligibility for biologic therapies, Apply evidence-based guidelines and the latest clinical data when selecting treatment for patients with uncontrolled persistent asthma, Implement patient education and communication tactics in personalized treatment plans to improve patient adherence, self-management, and quality of life.

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undefined - Benjamin Levy, MD - Candid Conversations About NSCLC—Live From Chicago: Navigating Immunotherapies and Combinations in the Search for the Best Strategy for Each Patient

Benjamin Levy, MD - Candid Conversations About NSCLC—Live From Chicago: Navigating Immunotherapies and Combinations in the Search for the Best Strategy for Each Patient

Go online to PeerView.com/WED860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Non–small cell lung cancer (NSCLC) is one of the tumor types where the novel class of cancer immunotherapies—the immune checkpoint inhibitors—has had the biggest impact and certainly become a major component of the treatment arsenal in the advanced disease setting. While the approval and availability of an increasing number and variety of immunotherapeutic agents and combinatorial options has been welcomed by clinicians and patients alike, clinical decision-making has also become quite complicated. How to identify the right candidates for immunotherapy? What biomarkers should be tested to guide candidate selection? And which agent or combination to use for individual patients? All these questions and more are explored in this engaging and entertaining educational session based on a live symposium held adjunct to the 2019 American Society of Clinical Oncology Annual Meeting (ASCO 2019). Modeled after the format of a late-night talk show, this activity merges focused talks on defined topics with personal story-telling, candid interviews, and interactive debates/discussions among top experts. Upon completion of this activity, participants should be better able to: Evaluate the efficacy/safety profiles and clinical roles of approved and investigational immunotherapies and combinations in the frontline setting and beyond in advanced/metastatic NSCLC, Assess the role of predictive biomarkers (PD-L1, TMB) and other tumor-, patient-, and treatment-related factors that should be taken into consideration as part of individualized treatment planning and selection for patients with NSCLC, Describe key new research directions and clinical trials with immunotherapies aiming to refine, expand, and maximize their use throughout the lung cancer continuum, including novel immune targets or combinations and biomarkers in advanced settings, as well as potentially curative approaches in earlier stages of NSCLC, Implement individualized, evidence-based, patient-centric treatment plans involving immunotherapies and/or combinations for patients with NSCLC.