PeerView Immunology & Transplantation CME/CNE/CPE Video Podcast

Go online to PeerView.com/XEJ860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Multiple new drug approvals and positive clinical trial outcomes have set the stage for the wider integration of novel therapeutics across the treatment spectrum of hepatocellular carcinoma (HCC). These developments have established multiple targeted and immunotherapy agents as options in advanced disease while also mapping potential future applications in intermediate stage HCC and beyond. Future care will depend on the successful integration of newer tyrosine kinase inhibitor (TKI)-based approaches with established and emerging immune checkpoint inhibitors across patient populations and lines of therapy. This PeerView “How I Think, How I Treat” activity, based on a symposium held during the 2019 American Society of Clinical Oncology Annual Meeting in Chicago, offers an inside look at how experts translate important new data and navigate the current HCC landscape in order to provide the most benefit for their patients. This activity also features important insights on how to utilize newly approved TKIs and checkpoint inhibitors across disease and treatment settings, as well as provides expert thoughts on the next wave of emerging solutions that leverage the power of novel therapies across the continuum of HCC. Upon completion of this activity, participants should be better able to: Summarize emerging clinical evidence on the use of novel systemic treatments, including targeted and immunotherapeutic agents, in a range of HCC treatment settings and populations, Apply recent safety and efficacy data on targeted therapies into clinical practice to enhance aspects of HCC care, including treatment sequencing and managing treatment-related adverse events, Integrate immunotherapeutic strategies for the management of patients with advanced HCC, including through optimal treatment selection and via management of immune-related adverse events, Identify innovative treatment strategies currently being assessed in clinical trials across the spectrum of HCC, such as immunotherapy combinations, combinations of novel agents with locoregional therapies, and early transition to systemic treatment, among others.

Go online to PeerView.com/XHY860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, experts in dermatology and pediatric primary care discuss the management of patients with atopic dermatitis. A patient also joins the discussion to provide unique perspectives on living with atopic dermatitis and interacting with healthcare providers. Upon completion of this activity, participants should be better able to: Diagnose atopic dermatitis in individual patients based on recognition of clinical manifestations and application of current diagnostic criteria and guidelines, Describe the mechanisms of action and clinical profiles of new and emerging topical and systemic therapies for atopic dermatitis, Select appropriate treatments for patients with atopic dermatitis based on current guideline recommendations, the safety and efficacy of available treatment options, comorbidities, and burden of disease, Employ shared decision-making approaches to create individualized treatment plans for atopic dermatitis, Implement patient/caregiver education strategies to improve adherence to atopic dermatitis treatment (eg, managing application-site pain associated with topical therapies) and assess the effects of treatment on patient quality of life

Go online to PeerView.com/GSV860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an asthma expert discusses the latest evidence and data on treatment for persistent asthma presented at the American Thoracic Society Conference 2019 in Dallas, Texas. Upon completion of this activity, participants should be better able to: Discuss the latest clinical data for the efficacy and safety of approved and emerging treatments for uncontrolled persistent asthma, Employ strategies to treat patients with uncontrolled persistent asthma in the context of late-breaking data and patient-, disease-, and therapy-related factors.

Go online to PeerView.com/XQR860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert in rheumatology discusses the role of novel therapeutic options in overcoming challenges associated with the management of patients with refractory rheumatoid arthritis. Upon completion of this activity, participants should be better able to: Recognize challenges associated with the management of refractory rheumatoid arthritis, Identify novel therapeutic options for rheumatoid arthritis in the context of mechanism of action, efficacy, and safety, Employ current evidence and expert recommendations into individualized treatment plans for patients with rheumatoid arthritis who have not achieved adequate disease control on previous therapies.

Go online to PeerView.com/EWW860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Melanoma was the first clinical setting in which the use of immune checkpoint inhibitors was validated, leading to their rapid integration into the management of advanced disease. More recently, checkpoint inhibitors, based on phase 3 evidence, have claimed a role in the adjuvant setting. The future of adjuvant therapy for high-risk resectable melanoma is bright, but achieving optimal care will depend on close collaboration between oncologists and surgeons, as well as the identification of patients who are excellent candidates for immune-based adjuvant therapy. In this activity, based on a recent live symposium, experts in oncology get to the heart of why immunotherapy is a rational and potent management strategy for patients with high-risk, resected melanoma, offer insights into the key studies that validated adjuvant immunotherapy in resectable disease, as well as clarify what the evidence from these trials means for the practice of surgical oncology. The panel of leading experts also synthesizes the clinical experience with adjuvant checkpoint inhibition and detail practical patient identification, dosing, and safety considerations that will make a difference in how you manage your patients. Upon completion of this activity, participants should be better able to: Describe the clinical role and rationale for use of immune-based therapy in stage III, resectable melanoma, Cite updated efficacy and safety findings regarding immune checkpoint inhibitors as an adjuvant option in surgically resected melanoma, including high-risk stage III disease, Recommend the use of adjuvant immunotherapy for eligible patients with resectable stage III melanoma, Manage immune-related and immune-mediated adverse events in patients with melanoma treated with immunotherapy after surgical resection.