The Psychedelic Revolution

03/19/25 • 48 min

We are in the midst of a psychedelic revolution with virtually every major academic medical institution in the US operating a psychedelic research lab. Psilocybin is one of the best studied of these substances, acting through a variety of mechanisms including BDNF generated neuroplasticity, anti-inflammatory immune modulation, neurotransmitter activation (serotonin HT2A/B, dopamine, glutamine), gut-brain axis support, and more, the active ingredient in "magic mushrooms" supports a high state of neural entropy which is believed to be a primary mechanism in the ability to rewire the brain and address old burdens with a new perspective.

With an impeccable safety profile and very compelling outcomes with a variety of mental health and neurological conditions ranging from depression and anxiety to addiction, trauma, and dementia, psilocybin remains a Schedule 1 drug and illegal in most states and municipalities. There are, however, a few exceptions.

Based on the 2018/19 FDA designation as a Breakthrough Therapy, the doors to research are open wider than ever. And under the protection of the Religious Freedom Restoration Act of 1993-federal legislation passed to offer protected use of entheogenic plants within the context of sincere spiritual practice. There is a pathway to access beyond the limited geographic decriminalization offered in Oregon and Colorado. Listen in as I chat with the founders of one such non-profit church, rooted in Naturopathic Medicine principles, as they safely and responsibly bring the healing power of psilocybin to those who can benefit.

Speaker Bios:

Rev. Leah Linder, ND

With a background in biochemistry and emergency medicine, Leah is a naturopathic physician trained in psychedelic-assisted therapy with deep expertise in natural supplement formulation and manufacturing. She is a Master Gardener, experienced educator, and ordained minister.

Rev. Pam Conboy

With a background in biology, Pam was trained as a clinical laboratorian and is currently a doctoral student in naturopathic medicine. She is an IIN-certified health coach, trained psychedelic facilitator, medical marketing business development entrepreneur, and ordained minister.

[email protected]

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Thanks for listening in. I hope you found today’s episode interesting and came away with a few insights you can apply to your practice. If you want to go deeper on this topic or anything else, please visit https://todayspractitioner.com and consider registering for our weekly newsletter as well.

Thanks again and I hope you’ll join us next time.

Speaker Bios:

Rev. Leah Linder, ND

Rev. Pam Conboy

[email protected]

Related Content:

Setas Seminary Site: http://setasseminary.org/

Become a Setas Seminary Member (free and open to all US adults):

https://www.setasseminary.org/become-a-member/

Subscribe to the Free Weekly Setas Seminary Newsletter:

https://www.setasseminary.org/newsletter/

Thanks again and I hope you’ll join us next time.

Previous Episode

Resolving Inflammation with Botanicals, Nutrients, and Lifestyle Changes

Today we’re talking with Dr. Lexi Loch about Inflammation. Inflammation can be life-saving and also life-threatening. The acute inflammatory response helps the body heal, defend, and repair. However, when inflammation persists without resolution, chronic inflammation ensues. Chronic inflammation is one of the biggest contributors to chronic health conditions. Prioritizing lifestyle and nutrition changes can make a huge impact, along with targeted supplementation. Curcumin with turmeric essential oil has been shown to modulate almost every inflammatory pathway in the body, while also promoting resolution of inflammation. Boswellia excels at modulating inflammation from the 5-LOX pathway, which can translate to reductions in lung, gastrointestinal, and joint inflammation. Omega-3 fatty acids are precursors to compounds called specialized pro-resolving mediators (SPMs), like resolvins and protectins, that help resolve inflammation.

Dr. Lexi Loch, ND received her Doctorate in Naturopathic Medicine from the National University of Natural Medicine, where she graduated with highest honors. In addition to her practice, she is a medical writer and editor, researcher, educator, and patient advocate. Her articles have been published in various natural health periodicals and reference books. Prior to her education as a physician, Dr. Loch worked in veterinary medicine as a certified veterinary technician. She is also an accomplished athlete, playing collegiate volleyball and participating in overseas tournaments, an avid snowboarder, and has been world-ranked in downhill longboarding.