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Goodpods has curated a list of the 10 best No Priors: Artificial Intelligence | Technology | Startups episodes, ranked by the number of listens and likes each episode have garnered from our listeners. If you are listening to No Priors: Artificial Intelligence | Technology | Startups for the first time, there's no better place to start than with one of these standout episodes. If you are a fan of the show, vote for your favorite No Priors: Artificial Intelligence | Technology | Startups episode by adding your comments to the episode page.

DeepSeek, Deep Research, and 2025 Predictions with Sarah and Elad
No Priors: Artificial Intelligence | Technology | Startups
02/07/25 • 22 min
This week on No Priors, Sarah and Elad celebrate the 100th episode! They dive into the biggest AI stories of 2025, breaking down DeepSeek—truth vs. hype, the rapid consumer adoption, and the real cost of training the models. They debate model commoditization and the value of being a frontier model provider vs. building on existing work. Plus, they unpack OpenAI’s new Deep Research release and the latest on Stargate. Finally, they share bold predictions for 2025, covering robots, autonomous vehicles, local AI models, emerging data-generation strategies, and reasoning breakthroughs.
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Show Notes:
0:00 Introduction
0:19 DeepSeek
5:38 Are models commoditizing?
8:33 DeepSeek’s consumer adoption
9:16 OpenAI’s Deep Research release
13:30 Stargate
15:04 Elad & Sarah’s Predictions for 2025
1 Listener

Building the Platform for Scientific Breakthrough, with Noubar Afeyan of Moderna and Flagship Pioneering
No Priors: Artificial Intelligence | Technology | Startups
02/27/25 • 40 min
This week on No Priors, Sarah sits down with Noubar Afeyan, Co-founder and CEO of Flagship Pioneering, the biotech firm behind groundbreaking companies like Moderna. They explore how Flagship creates the conditions for scientific breakthroughs, tackles regulatory uncertainty, and pushes the boundaries of discovery. Noubar shares insights on AI’s role in healthcare, the challenges of bringing new therapies to market, and lessons learned from past pandemics. He also discusses Flagship’s platform approach to biotech innovation and introduces the idea of polyintelligence.
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Show Notes:
0:00 Introduction
0:48 Founding Flagship
5:51 Fostering environments for emergence
11:17 Expanding into new frontiers
14:26 Developing technology amid regulatory uncertainty and risk
19:12 How Flagship has evolved
22:47 AI applications in healthcare
27:30 Bottlenecks in bringing new therapies to market
32:20 Lessons for the next pandemic
34:11 Building a platform
38:10 Polyintelligence
1 Listener

How Harvey AI is Changing the Legal Industry with Winston Weinberg
No Priors: Artificial Intelligence | Technology | Startups
02/14/25 • 49 min
This week on No Priors, Sarah sits down with Harvey cofounder and CEO Winston Weinberg. Harvey is one of the leading application layer AI companies, building domain-specific AI for law firms, professional service providers, and the Fortune 500. They are already working with companies like Bridgewater, KKR, PWC, and O’Melveny with over $500M in funding from OpenAI, Sequoia, Kleiner, GV and Elad and Sarah. In this episode, Sarah and Winston cover AI product strategy, the future of professional services, company values, keeping up with research, and the law industry of the future.
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Show Notes:
0:00 Introduction
2:39 Harvey’s founding story
3:46 Capability improvement
6:39 Building teams around AI capabilities
9:17 End to end task completion
12:37 Beginning with large industry leaders
17:21 Working with users skeptical of automation
20:40 Being a lawyer today and in the future
26:02 Adapting product for other domains
26:58 Hiring philosophy at Harvey
30:39 Lessons and mistakes as a founder
32:53 Personal drive
40:21 Advice to other founders
44:35 Prediction for next ChatGPT moment
1 Listener

Launching AI products with Braintrust’s CEO Ankur Goyal
No Priors: Artificial Intelligence | Technology | Startups
10/08/24 • 38 min
Today on No Priors, Elad is joined by Ankur Goyal, founder and CEO of Braintrust. Braintrust enables companies like Notion, Airtable, Instacart, Zapier, and Vercel to deploy AI solutions at scale by efficiently evaluating and managing complex, non-deterministic AI applications. Ankur shares his insights into emerging trends in the use of AI tooling and coding languages, the rise of open-source, and the future of data infrastructure. Ankur also reflects on building resilient AI products, his philosophy on coding as a CEO, and the importance of a startup’s initial customer base.
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Show Notes:
(0:00) Introduction
(0:38) Ankur’s path to Braintrust
(3:05) Braintrust’s solution
(5:46) AI tooling trends
(7:58) Instruction tuning vs. fine-tuning
(8:57) Open-source AI adoption
(10:42) Future of data infrastructure and synthetic data
(14:45) Designing technical interviews
(18:04) Rethinking agent-based approaches
(19:34) Building out an AI team
(23:35) Typescript as the language of AI
(25:12) The shift away from using frameworks
(26:02) Vendor consolidation among enterprises
(27:16) Coding as a CEO
(30:16) Collaborating with customers
(33:00) Future of Braintrust and evals
1 Listener

Building Hard Tech in Hard Markets: Kyle Vogt on Cruise, Twitch, and The Bot Company
No Priors: Artificial Intelligence | Technology | Startups
02/20/25 • 38 min
Kyle Vogt joins Sarah and Elad on this week’s episode of No Priors. A serial entrepreneur, Kyle co-founded Twitch, transforming live streaming, and later Cruise, the autonomous vehicle company acquired by GM for $1 billion. Now he’s taking on AI-powered home robotics with The Bot Company. In this episode, Kyle shares his journey building transformative tech companies, the challenges of scaling autonomous systems, and why he believes home robots are the next frontier. They also discuss the parallels between AVs and robotics, overcoming consumer skepticism, US vs. China manufacturing, and the policies needed to foster a competitive robotics industry.
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Show Notes:
0:00 Introduction
0:29 Founding Cruise
3:12 Tesla vs. Waymo approach
4:44 Scaling autonomous vehicles
10:03 The Bot Company
16:35 Deploying robots in the home
17:56 Parallels between robots and AV markets
20:51 Personifying robots and overcoming consumer skepticism
25:00 Timeline on consumer robots
26:47 Chinese vs. US manufacturing
29:15 Fostering a competitive domestic robotics industry
34:00 Lessons from Cruise & personal philosophies
1 Listener

How AI Agents Are Transforming Customer Support, with Decagon’s Jesse Zhang
No Priors: Artificial Intelligence | Technology | Startups
01/16/25 • 30 min
Today on No Priors, co-founder and CEO of Decagon, Jesse Zhang, joins Elad to discuss the future of agentic customer support. Decagon provides AI-powered customer interactions for companies like Rippling, Notion, Duolingo, Classpass, Substack, Vanta, Eventbrite, and more. Jesse shares the thesis behind starting Decagon, why he sees customer support as the ideal entry point for agentic technology, and what areas of AI excite him most. They also discuss voice-based interfaces, issues with latency in current capabilities, and the connection between young math olympiad communities and today’s AI startups.
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Show Notes:
0:00 Introduction
0:30 Starting Decagon
3:15 Business impact of adopting agents for customer support and customer ops
8:00 AI infrastructure and models for customer success agents
12:05 Voice-based capabilities and text-to-speech engines
15:00 Combatting latency
16:25 Crossover of math and AI communities
21:12 Exciting areas of AI
25:29 Strengths and weaknesses of agents
1 Listener

Waymo’s Journey to Full Autonomy: AI Breakthroughs, Safety, and Scaling
No Priors: Artificial Intelligence | Technology | Startups
10/24/24 • 44 min
In this episode of No Priors, Dmitri Dolgov, Co-CEO of Waymo, joins Sarah and Elad to explore the evolution and advancements of Waymo's self-driving technology from its inception at Google to its current real-world deployment. Dmitri also shares insights into the technological breakthroughs and complexities of achieving full autonomy, the design innovations of Waymo’s sixth generation driverless cars, and the broader applications of Waymo’s advanced technology. They also discuss Waymo's strategic approach to scaling amidst regulation, deployment in cities like Phoenix and San Francisco, and the transformative potential of autonomous driving on car ownership and urban infrastructure.
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Shownotes:
00:00 Introduction
00:15 History of Self-Driving at Google
00:29 DARPA Challenges and Early Involvement
01:39 Formation of Waymo
01:53 Industry Lineage and Early Skepticism
03:05 Initial Goals and Milestones
4:33 Pivot to Full Autonomy
04:50 Scaling and Deployment
05:29 Generational Breakthroughs
06:59 Choosing Deployment Cities
09:26 Technological Advancements
11:01 Evaluating Safety
14:41 Regulatory Stance and Trust
16:52 Future of Autonomous Driving
23:19 Business Strategy and Partnerships
26:06 Changing Urban Mobility Trends
26:40 Challenges and Misconceptions in Self-Driving Timelines
28:43 The Role of Traditional OEMs in an Autonomous Future
30:54 Designing Cars for Autonomous Ride-Hailing
33:42 Scaling Responsibly
35:18 Generalizability and Future Applications of AI
37:10 The Complexity of Achieving Full Autonomy
42:58 The Importance of Data and Iteration in AI Development
46:13 Reflecting on the Journey and Future of Waymo
1 Listener

The argument for humanoid AI robots with Brett Adcock from Figure
No Priors: Artificial Intelligence | Technology | Startups
04/04/24 • 38 min
Humans are always doing work that is dull or dangerous. Brett Adcock, the founder and CEO of Figure AI, wants to build a fleet of robots that can do everything from work in a factory or warehouse to folding your laundry in the home. Today on No Priors, Sarah got the chance to talk with Brett about how a company that is only 21 months old has already built humanoid robots that not only walk the walk by performing tasks like item retrieval and making a cup of coffee but they also talk the talk through speech to speech reasoning.
In this episode, Brett and Sarah discuss why right now is the correct time to build a fleet of AI robots and how implementation in industrial settings will be a stepping stone into AI robots coming into the home. They also get into how Brett built a team of world class engineers, commercial partnerships with BMW and OpenAI that are accelerating their growth, and the plan to achieve social acceptance for AI robots.
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Show Notes:
(0:00) Brett’s background
(3:09) Figure AI Thesis
(5:51) The argument for humanoid robots
(7:36) Figure AI public demos
(12:38) Mitigating risk factors
(15:20) Designing the org chart and finding the team
(16:38) Deployment timeline
(20:41) Build vs buy and vertical integration
(23:04) Product management at Figure
(28:37) Corporate partnerships
(31:58) Humans at home
(33:38) Social acceptance
(35:41) AGI vs the robots

How the ARC Prize is democratizing the race to AGI with Mike Knoop from Zapier
No Priors: Artificial Intelligence | Technology | Startups
06/11/24 • 26 min
The first step in achieving AGI is nailing down a concise definition and Mike Knoop, the co-founder and Head of AI at Zapier, believes François Chollet got it right when he defined general intelligence as a system that can efficiently acquire new skills. This week on No Priors, Miked joins Elad to discuss ARC Prize which is a multi-million dollar non-profit public challenge that is looking for someone to beat the Abstraction and Reasoning Corpus (ARC) evaluation.
In this episode, they also get into why Mike thinks LLMs will not get us to AGI, how Zapier is incorporating AI into their products and the power of agents, and why it’s dangerous to regulate AGI before discovering its full potential.
Show Links:
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Follow us on Twitter: @NoPriorsPod | @Saranormous | @EladGil | @mikeknoop
Show Notes:
(0:00) Introduction
(1:10) Redefining AGI
(2:16) Introducing ARC Prize
(3:08) Definition of AGI
(5:14) LLMs and AGI
(8:20) Promising techniques to developing AGI
(11:0) Sentience and intelligence
(13:51) Prize model vs investing
(16:28) Zapier AI innovations
(19:08) Economic value of agents
(21:48) Open source to achieve AGI
(24:20) Regulating AI and AGI

Revolutionizing Customer Success with Agency’s Elias Torres
No Priors: Artificial Intelligence | Technology | Startups
12/19/24 • 31 min
Today on No Priors, Sarah sits down with Elias Torres, CEO and founder of Agency, an AI agent for customer success teams. Elias shares his journey from growing up in Nicaragua to founding several companies, leading engineering at HubSpot, and selling Drift for $1B. He also discusses his work consulting with OpenAI in 2022, which deepened his understanding of the business opportunity LLMs presented and inspired him to start Agency. In this episode, Elias offers a unique perspective on the future of AI and customer success, explaining how current software has fallen short and his vision for a new generation where customers have direct relationships, spend less time on tasks, and have software working invisibly on their behalf. They also discuss the evolving landscape of hiring as teams shrink, and Elias reveals his ambitious plan to reach $1B in revenue with fewer than 100 employees.
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Follow us on Twitter: @NoPriorsPod | @Saranormous | @EladGil | @EliasT
Show notes:
0:00 Introduction
0:34 Elias’ journey to entrepreneurship
2:36 Growing HubSpot to IPO and founding Drift
6:19 Consulting with OpenAI, learning about LLMs, and diving into AI
9:35 Founding Agency to focus on customer success and AI-driven solutions
11:40 What will a customer experience look like in 5 years?
15:48 Company building in an era of AI, as a 5th time founder
18:32 Reducing headcount while raising the bar on hiring
20:35 Key challenges in building Agency and crafting a standout product
23:06 Addressing software flaws and transitioning to an era of intuitive, self-operating solutions
26:27 Timeline for the next-gen software revolution + the power of building from first principles
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FAQ
How many episodes does No Priors: Artificial Intelligence | Technology | Startups have?
No Priors: Artificial Intelligence | Technology | Startups currently has 106 episodes available.
What topics does No Priors: Artificial Intelligence | Technology | Startups cover?
The podcast is about Entrepreneurship, Podcasts, Technology and Business.
What is the most popular episode on No Priors: Artificial Intelligence | Technology | Startups?
The episode title 'Building Hard Tech in Hard Markets: Kyle Vogt on Cruise, Twitch, and The Bot Company' is the most popular.
What is the average episode length on No Priors: Artificial Intelligence | Technology | Startups?
The average episode length on No Priors: Artificial Intelligence | Technology | Startups is 37 minutes.
How often are episodes of No Priors: Artificial Intelligence | Technology | Startups released?
Episodes of No Priors: Artificial Intelligence | Technology | Startups are typically released every 7 days.
When was the first episode of No Priors: Artificial Intelligence | Technology | Startups?
The first episode of No Priors: Artificial Intelligence | Technology | Startups was released on Feb 2, 2023.
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