1.16 - Prof David Nutt: The Neuroscience Of Psychedelics, Addiction, And How Drugs Help Us Understand The Brain
09/10/21 • 61 min
Prof David Nutt is Neuropsychopharmacologist specialising in the research of drugs that affect the brain and conditions such as addiction, anxiety, and sleep.
David is the chairman of Drug Science, a non-profit which he founded in 2010 to provide independent, evidence-based information on drugs. Nutt is the deputy head of the Centre for Psychedelic Research at Imperial College London. He and his team have published research into psilocybin for TRD, as well as neuroimaging studies investigating psilocybin, MDMA, LSD, and DMT.
In this episode:
- How drugs help our understanding of the brain
- Impact of prohibition on investigation and research
- Key terms - decriminalisation, depenalisation, legalisation
- Drug harm profiles - alcohol, lsd, mdma, psilocybin
- Physiology and psychology of addiction
- Brain-mind interplay
- The psychedelic experience and its phenomena
- The default mode network
- Functional connectivity
- Neuroplasticity
- Why profound alterations in consciousness permit long-term changes
- Serotonin's role in depression
- Psilocybin vs SSRIs and the 5HT2a receptor
- Psychedelics vs Psychedelic-assisted psychotherapies
Links:
Recent paper exploring Psilocybin vs SSRIs:
Serotonin and brain function: a tale of two receptors
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Prof David Nutt is Neuropsychopharmacologist specialising in the research of drugs that affect the brain and conditions such as addiction, anxiety, and sleep.
David is the chairman of Drug Science, a non-profit which he founded in 2010 to provide independent, evidence-based information on drugs. Nutt is the deputy head of the Centre for Psychedelic Research at Imperial College London. He and his team have published research into psilocybin for TRD, as well as neuroimaging studies investigating psilocybin, MDMA, LSD, and DMT.
In this episode:
- How drugs help our understanding of the brain
- Impact of prohibition on investigation and research
- Key terms - decriminalisation, depenalisation, legalisation
- Drug harm profiles - alcohol, lsd, mdma, psilocybin
- Physiology and psychology of addiction
- Brain-mind interplay
- The psychedelic experience and its phenomena
- The default mode network
- Functional connectivity
- Neuroplasticity
- Why profound alterations in consciousness permit long-term changes
- Serotonin's role in depression
- Psilocybin vs SSRIs and the 5HT2a receptor
- Psychedelics vs Psychedelic-assisted psychotherapies
Links:
Recent paper exploring Psilocybin vs SSRIs:
Serotonin and brain function: a tale of two receptors
Support the podcast:
Support the mission:
Donate to Mind Medicine Australia
Support this show http://supporter.acast.com/mind-medicine-australia.
Become a member at https://plus.acast.com/s/mind-medicine-australia.
Hosted on Acast. See acast.com/privacy for more information.
Previous Episode
1.15 - Dennis McKenna: Catalysing A Global Transformation Of Human Consciousness
Dennis McKenna is an Ethnopharmacolgist, research pharmacist, lecturer, and author.
Dennis is a founding member and director of ethnographic research at the Heffter Research Institute, a non-profit organization involved in investigating the potential of therapeutic use of drugs. He is the brother of the famous psychedelic advocate Terence McKenna.
In this episode:
- Preserving indigenous practice, challenges we face
- Mckenna Academy of Natural Philosophy
- The brain as a reducing valve of reality
- The mind-brain problem
- Psychedelics bring the background forward
- Serotonin
- Consciousness and symbiosis
- What research questions should be asked in the next 5-10 years
- Who will be the gatekeepers of these medicines
- The need to arm psychiatrists and mental health practitioners with psychedelics
Support the podcast:
Support the mission:
Donate to Mind Medicine Australia
Support this show http://supporter.acast.com/mind-medicine-australia.
Become a member at https://plus.acast.com/s/mind-medicine-australia.
Hosted on Acast. See acast.com/privacy for more information.
Next Episode
1.17 - Adam Gazzaley MD, PhD: Bridging Between The Molecular And Neurophysiological Mechanisms Of Psychedelics To Clinical Outcomes
Adam Gazzaley MD, PhD is a neuroscientist, neurologist, inventor, author, photographer, entrepreneur and investor.
Adam obtained an M.D. and a Ph.D. in Neuroscience at the Mount Sinai School of Medicine in New York, completed Neurology residency at the University of Pennsylvania, and postdoctoral training in cognitive neuroscience at University of California, Berkeley. He is now the David Dolby Distinguished Professor in Neurology, Physiology and Psychiatry at University of California, San Francisco and the Founder / Executive Director of Neuroscape, a translational neuroscience center engaged in technology creation and scientific research.
In this episode:
- Humans as information seeking creatures
- How technology has challenged our brain
- Bottom-up and top-down attention
- Advancing psychedelic research
- The role of context in experience outcomes
- The mind as a functional product of the brain
- Neuroplasticity (experience-dependent plasticity and self-directed plasticity)
- Creating an interpretable real-time experience landscape
- Psychedelics in neurodegenerative illness
Links:
Support the podcast:
Support the mission:
Donate to Mind Medicine Australia
Support this show http://supporter.acast.com/mind-medicine-australia.
Become a member at https://plus.acast.com/s/mind-medicine-australia.
Hosted on Acast. See acast.com/privacy for more information.
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