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Invest Like the Best with Patrick O'Shaughnessy - Marc Andreessen - The Battle For Tech Supremacy - [Invest Like the Best, EP.410]

Marc Andreessen - The Battle For Tech Supremacy - [Invest Like the Best, EP.410]

02/11/25 • 83 min

2 Listeners

Invest Like the Best with Patrick O'Shaughnessy

My guest today is Marc Andreessen. Marc is a co-founder of Andreessen Horowitz and one of Silicon Valley's most influential figures. He combines deep technical knowledge from his engineering background with broad historical understanding and strategic thinking about societal patterns. He last joined me on Invest Like the Best in 2021, and the playing field looks a lot different today. Marc goes deep on the seismic shifts reshaping technology and geopolitics. We discuss DeepSeek's open-source AI and what it means for the technological rivalry between America and China, his perspective on the evolution of power structures, and the transformation of the venture capital industry as a whole. Please enjoy my conversation with Marc Andreessen.

Subscribe to Colossus Review.

For the full show notes, transcript, and links to mentioned content, check out the episode page here.

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This episode is brought to you by Ramp. Ramp’s mission is to help companies manage their spend in a way that reduces expenses and frees up time for teams to work on more valuable projects. Ramp is the fastest-growing FinTech company in history, and it’s backed by more of my favorite past guests (at least 16 of them!) than probably any other company I’m aware of. Go to Ramp.com/invest to sign up for free and get a $250 welcome bonus.

This episode is brought to you by Ridgeline. Ridgeline has built a complete, real-time, modern operating system for investment managers. It handles trading, portfolio management, compliance, customer reporting, and much more through an all-in-one real-time cloud platform. I think this platform will become the standard for investment managers, and if you run an investing firm, I highly recommend you find time to speak with them. Head to ridgelineapps.com to learn more about the platform.

This episode is brought to you by Alphasense. AlphaSense has completely transformed the research process with cutting-edge AI technology and a vast collection of top-tier, reliable business content. Imagine completing your research five to ten times faster with search that delivers the most relevant results, helping you make high-conviction decisions with confidence. Invest Like the Best listeners can get a free trial now at Alpha-Sense.com/Invest and experience firsthand how AlphaSense and Tegus help you make smarter decisions faster.

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Editing and post-production work for this episode was provided by The Podcast Consultant (https://thepodcastconsultant.com).

Show Notes:

(00:00:00) Learn about Ramp, Ridgeline, & Alphasense

(00:06:00) Introduction to DeepSeek's R1

(00:07:24) DeepSeek's Global Impact

(00:09:25) AI's Ubiquity and Future

(00:10:36) Winners and Losers in the AI Race

(00:14:22) The New AI Cold War

(00:16:34) China's Technological Ambitions

(00:21:31) Open Source and Intellectual Property

(00:27:48) The Role of Open Source in AI Development

(00:30:02) National Interests vs. Global Competition

(00:37:25) The Future of Capital Allocation

(00:45:41) Challenges of Sustaining Private Partnerships

(00:46:34) Building a Franchise Business

(00:48:27) The Role of Political Operations

(00:50:51) The Dynamics of Power and Elites

(01:01:44) Technological Change and Its Implications

(01:13:37) The Future of Robotics and Supply Chains

(01:21:09) American Dynamism and Defense Technology

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My guest today is Marc Andreessen. Marc is a co-founder of Andreessen Horowitz and one of Silicon Valley's most influential figures. He combines deep technical knowledge from his engineering background with broad historical understanding and strategic thinking about societal patterns. He last joined me on Invest Like the Best in 2021, and the playing field looks a lot different today. Marc goes deep on the seismic shifts reshaping technology and geopolitics. We discuss DeepSeek's open-source AI and what it means for the technological rivalry between America and China, his perspective on the evolution of power structures, and the transformation of the venture capital industry as a whole. Please enjoy my conversation with Marc Andreessen.

Subscribe to Colossus Review.

For the full show notes, transcript, and links to mentioned content, check out the episode page here.

-----

This episode is brought to you by Ramp. Ramp’s mission is to help companies manage their spend in a way that reduces expenses and frees up time for teams to work on more valuable projects. Ramp is the fastest-growing FinTech company in history, and it’s backed by more of my favorite past guests (at least 16 of them!) than probably any other company I’m aware of. Go to Ramp.com/invest to sign up for free and get a $250 welcome bonus.

This episode is brought to you by Ridgeline. Ridgeline has built a complete, real-time, modern operating system for investment managers. It handles trading, portfolio management, compliance, customer reporting, and much more through an all-in-one real-time cloud platform. I think this platform will become the standard for investment managers, and if you run an investing firm, I highly recommend you find time to speak with them. Head to ridgelineapps.com to learn more about the platform.

This episode is brought to you by Alphasense. AlphaSense has completely transformed the research process with cutting-edge AI technology and a vast collection of top-tier, reliable business content. Imagine completing your research five to ten times faster with search that delivers the most relevant results, helping you make high-conviction decisions with confidence. Invest Like the Best listeners can get a free trial now at Alpha-Sense.com/Invest and experience firsthand how AlphaSense and Tegus help you make smarter decisions faster.

-----

Editing and post-production work for this episode was provided by The Podcast Consultant (https://thepodcastconsultant.com).

Show Notes:

(00:00:00) Learn about Ramp, Ridgeline, & Alphasense

(00:06:00) Introduction to DeepSeek's R1

(00:07:24) DeepSeek's Global Impact

(00:09:25) AI's Ubiquity and Future

(00:10:36) Winners and Losers in the AI Race

(00:14:22) The New AI Cold War

(00:16:34) China's Technological Ambitions

(00:21:31) Open Source and Intellectual Property

(00:27:48) The Role of Open Source in AI Development

(00:30:02) National Interests vs. Global Competition

(00:37:25) The Future of Capital Allocation

(00:45:41) Challenges of Sustaining Private Partnerships

(00:46:34) Building a Franchise Business

(00:48:27) The Role of Political Operations

(00:50:51) The Dynamics of Power and Elites

(01:01:44) Technological Change and Its Implications

(01:13:37) The Future of Robotics and Supply Chains

(01:21:09) American Dynamism and Defense Technology

Previous Episode

undefined - Graham Duncan - Talent Whisperer - [Invest Like the Best, EP.409]

Graham Duncan - Talent Whisperer - [Invest Like the Best, EP.409]

My guest today is Graham Duncan. This conversation will make you think about your life in new ways. This is a two-hour segment of a 4.5-hour interview I did with Graham last year. It stands alone as remarkable, but those who subscribe to Colossus Review will gain access to the full conversation. This will be true in future issues, too.

In 2006, in his early 30s, Graham convinced Stuart Miller, CEO of home construction company Lennar, to let him manage $50 million of his family's wealth. A year later, Miller gave him the rest of his capital outside of Lennar. That investment turned into East Rock, where Graham built an incredible investing track record managing billions for a select group of families by focusing on people.

Our conversation explores a wide range of topics—from what makes a great investment partnership to the power of positive feedback loops to starting a restaurant.

I’m thankful to Graham for showing me the way so many times and for being willing to be so incredibly open in this conversation. Please enjoy this discussion with Graham Duncan.

Subscribe to Colossus Review.

For the full show notes, transcript, and links to mentioned content, check out the episode page here.

-----

This episode is brought to you by Ramp. Ramp’s mission is to help companies manage their spend in a way that reduces expenses and frees up time for teams to work on more valuable projects. Ramp is the fastest-growing FinTech company in history, and it’s backed by more of my favorite past guests (at least 16 of them!) than probably any other company I’m aware of. Go to Ramp.com/invest to sign up for free and get a $250 welcome bonus.

This episode is brought to you by Ridgeline. Ridgeline has built a complete, real-time, modern operating system for investment managers. It handles trading, portfolio management, compliance, customer reporting, and much more through an all-in-one real-time cloud platform. I think this platform will become the standard for investment managers, and if you run an investing firm, I highly recommend you find time to speak with them. Head to ridgelineapps.com to learn more about the platform.

This episode is brought to you by Alphasense. AlphaSense has completely transformed the research process with cutting-edge AI technology and a vast collection of top-tier, reliable business content. Imagine completing your research five to ten times faster with search that delivers the most relevant results, helping you make high-conviction decisions with confidence. Invest Like the Best listeners can get a free trial now at Alpha-Sense.com/Invest and experience firsthand how AlphaSense and Tegus help you make smarter decisions faster.

-----

Editing and post-production work for this episode was provided by The Podcast Consultant (https://thepodcastconsultant.com).

Show Notes:

(00:00:00) Learn about Ramp, Ridgeline, & Alphasense

(00:05:12) Intro to Graham

(00:05:54) Launching Colossus Review

(00:08:05) The Principal-Agent Dynamic

(00:10:47) Navigating Financial Crises

(00:13:22) The Right Grip in Investing

(00:17:32) Seeding and Investment Strategies

(00:21:37) Defining 'Commercial' and Its Implications

(00:26:31) The Role of Laziness and Prolific Output

(00:28:20) Finding the Right People and Positive Feedback Loops

(00:37:21) Navigating Career Transitions and Motivations

(00:43:05) Understanding Source Dynamics

(00:50:07) Key Criteria for a Great CIO

(00:59:43) Structuring Relationships with CIOs

(01:03:40) Managing Ambiguity and Protecting Mental Clarity

(01:15:09) The Importance of Source in Business

(01:17:49) Designing Physical Spaces for...

Next Episode

undefined - Ravi Gupta - AI or Die - [Invest Like the Best, EP.411]

Ravi Gupta - AI or Die - [Invest Like the Best, EP.411]

My guest today is Ravi Gupta. Ravi is a Partner at Sequoia Capital and a host on Glue Guys, a podcast on the Colossus network that intersects business and sports. I wanted to have him back on Invest Like the Best to discuss his recent most recent blog post titled “AI or Die.” As both an investor and former Instacart operator and CFO, Ravi believes we're entering an era where the constraints that historically limited small teams are dissolving, creating unprecedented opportunities for those willing to embrace change aggressively. We discuss why traditional metrics of corporate success like headcount and process adherence may become liabilities, what it means to be a world-class reactor vs predictor, and how "magic per employee" and organizational agility will emerge as crucial measures of value creation. Please enjoy my conversation with Ravi Gupta.

Subscribe to Colossus Review.

For the full show notes, transcript, and links to mentioned content, check out the episode page here.

-----

This episode is brought to you by Ramp. Ramp’s mission is to help companies manage their spend in a way that reduces expenses and frees up time for teams to work on more valuable projects. Ramp is the fastest-growing FinTech company in history, and it’s backed by more of my favorite past guests (at least 16 of them!) than probably any other company I’m aware of. Go to Ramp.com/invest to sign up for free and get a $250 welcome bonus.

This episode is brought to you by Ridgeline. Ridgeline has built a complete, real-time, modern operating system for investment managers. It handles trading, portfolio management, compliance, customer reporting, and much more through an all-in-one real-time cloud platform. I think this platform will become the standard for investment managers, and if you run an investing firm, I highly recommend you find time to speak with them. Head to ridgelineapps.com to learn more about the platform.

This episode is brought to you by AlphaSense. AlphaSense has completely transformed the research process with cutting-edge AI technology and a vast collection of top-tier, reliable business content. Imagine completing your research five to ten times faster with search that delivers the most relevant results, helping you make high-conviction decisions with confidence. Invest Like the Best listeners can get a free trial now at Alpha-Sense.com/Invest and experience firsthand how AlphaSense and Tegus help you make smarter decisions faster.

-----

Editing and post-production work for this episode was provided by The Podcast Consultant (https://thepodcastconsultant.com).



Show Notes:

(00:00:00) Learn About Ramp, Ridgeline, & Alphasense

(00:06:00) Introduction to 'AI or Die' Essay

(00:06:29) Initial Reactions to AI Advancements

(00:08:24) The Concept of 'AI or Die'

(00:10:40) Adapting to Rapid Technological Change

(00:12:02) Using AI for Real Work

(00:13:58) Evaluating Company Agility and AI Integration

(00:18:58) The Cost of Employees in the AI Era

(00:25:36) AI's Impact on Business Strategy

(00:36:55) Changing Perspectives on AI Models

(00:37:50) The Importance of Context in AI

(00:39:09) Optimism in the Age of AI

(00:40:22) Predictors vs. Reactors

(00:42:54) AI Tools in Business Operations

(00:46:07) The Future of Small Teams and Efficiency

(00:49:01) Investing in the AI Era

(00:55:11) The Role of Board Members in AI Adoption

(00:57:22) Embracing Change with Humility

(00:59:17) The Ghost of Competition

(01:05:04) Seizing the AI Opportunity

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