
Unlocking the Longevity Secrets of Man’s Best Friend
12/11/18 • 52 min
Our guest today is Matt Kaeberlein, Ph.D., a globally recognized researcher and expert in the biology of aging. Dr. Kaeberlein’s research is based around the premise that understanding the molecular mechanisms of aging will lead to interventions that slow the onset and progression of age-related chronic conditions, such as cancer, diabetes, kidney disease, heart disease, Alzheimer’s and others. Dr. Kaeberlein received his Ph.D. from the Massachusetts Institute of Technology in 2002 advised by Leonard Guarente, and did his post-doctoral work with Stanley Fields in the Department of Genome Sciences at the University of Washington.
Dr. Kaeberlein’s expertise in dietary restriction, longevity genes for therapeutics, aging in dogs, and Rapamycin really shines in this conversation. We were lucky enough to really explore his background while sharing our collective love of dogs. The conversation explores many areas, including:
- What is the difference between calories restriction and dietary restriction
- What are the biggest challenges with the science
- How Matt thinks about tailored dietary advice
- Why Matt launched the Dog Aging Project
- What we can learn from his research with dogs
- What is Rapamycin and why he’s so interested in its effects
This conversation was incredibly illuminating and really fun. We hope you enjoy the episode and share it with your friends, family, and colleagues.
About Matt Show LinksOur guest today is Matt Kaeberlein, Ph.D., a globally recognized researcher and expert in the biology of aging. Dr. Kaeberlein’s research is based around the premise that understanding the molecular mechanisms of aging will lead to interventions that slow the onset and progression of age-related chronic conditions, such as cancer, diabetes, kidney disease, heart disease, Alzheimer’s and others. Dr. Kaeberlein received his Ph.D. from the Massachusetts Institute of Technology in 2002 advised by Leonard Guarente, and did his post-doctoral work with Stanley Fields in the Department of Genome Sciences at the University of Washington.
Dr. Kaeberlein’s expertise in dietary restriction, longevity genes for therapeutics, aging in dogs, and Rapamycin really shines in this conversation. We were lucky enough to really explore his background while sharing our collective love of dogs. The conversation explores many areas, including:
- What is the difference between calories restriction and dietary restriction
- What are the biggest challenges with the science
- How Matt thinks about tailored dietary advice
- Why Matt launched the Dog Aging Project
- What we can learn from his research with dogs
- What is Rapamycin and why he’s so interested in its effects
This conversation was incredibly illuminating and really fun. We hope you enjoy the episode and share it with your friends, family, and colleagues.
About Matt Show LinksPrevious Episode

Leading the Anti-Aging Revolution
Our guest today needs no introduction. It is the one and only Aubrey de Grey, a leading biomedical gerontologist, computer scientist, author, and entrepreneur whose work in longevity research is widely known and regularly referenced by many in the industry. He is the Chief Science Officer of the SENS Research Foundation and VP of New Technology Discovery at AgeX Therapeutics, Inc. In many respects, Aubrey is one of the most prominent, if not provocative figures in longevity science.
What makes Aubrey so provocative? Well, aside from his exceptionally long beard, he is the leading advocate of the controversial view that technology may one day enable humans to control the aging process and live well into our hundreds, or even thousands. As much as he believes this, he also knows that there are two main obstacles to achieving this utopia: money and time. While Aubrey’s research is funded by some of the biggest investors, he notes that the “pro-aging trance” has historically held them back. This conversation with Aubrey uncovers the theory of his pro-aging trance phenomena and many incredibly insightful details, including:
- How to remove senescent cells from our body
- What investments are at the top of his list
- Why investor Peter Thiel gave him $6M in funding
- What locations are hot spots for longevity research and innovation
- Where he’s seen the biggest breakthroughs
- When we can expect to benefit from his research
- What is the “pro-aging trance” and why it’s holding us back
This was a really exciting episode that gave the team a chance to hear a unique perspective. We hope you enjoy the episode and share it with your friends, family, and colleagues.
About Aubrey Show LinksNext Episode

Sex, Diet, and Mindfulness: Transforming Women’s Health with Dr. Maggie Ney
Dr. Maggie Ney – Co-Director of the Women’s Clinic and Licensed Naturopathic Doctor
Today’s episode is one of a kind. It’s a long overdue discussion on a topic that takes a backseat far too often - women’s health. To help us understand and explore this topic, we enlisted naturopathic doctor and co-director of the Women’s Clinic at Akasha, Dr. Maggie Ney.
Dr. Ney’s expertise is in healthy aging for women, with a special focus on hormone balancing. Her interest in this particular area is both incredibly relevant and highly personal. Having previously struggled with her own hormonal imbalance issues as a teenager, her enthusiasm is deeply rooted.
In our conversation with Dr. Ney, we cover a lot of really interesting topics ranging from recommendations for pregnant women to why she thinks hormone replacement therapy is critical after menopause and the what latest treatments for women’s sexual health. The conversation answers many important questions, including:
- Why she’s focused on women’s health
- What Maggie recommends for stress reduction
- How diet can impact your menstrual cycle
- What are the differences in fasting between men and women
- What changes has Maggie seen in women getting pregnant
- What Maggie recommends for women entering menopause
- What is the Mona Lisa Touch
This conversation covers so much important information; we can’t recommend it enough. Be sure to check out the incredible lightning round at the end of the episode, where Maggie shares specific advice for women of different age groups. We hope you enjoy the episode and share it with your friends, family, and colleagues.
About Dr. Ney Show Links- Chaste tree
- Rhodiola
- Ashwagandha
- Headspace
- Calm
- Glo
- The Women’s Health Initiative
- PRP
- Mona Lisa Touch
- Upgrade Labs
- Oura ring
- Muse
- Younger by Sara Gottfried
- The Hormone Cure by Sara Gottfried
- Dirty Genes by Ben Lynch
- Longevity Diet by Valter Longo
- The End of Alzheimer’s by Dale Bredesen
- Wheat Belly by William Davis
- Eat Fat Get Thin by Mark Hyman
If you like this episode you’ll love
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