#021 - Jan Nolta: Stem Cells & the Future of Regenerative Medicine

07/14/23 • 53 min

In this episode, we have Dr. Jan Nolta joining us to discuss her work in stem cells and regenerative medicine. Dr. Nolta explains the different types of stem cells, including adult stem cells and induced pluripotent stem cells (iPSCs), which have the potential to differentiate into any tissue in the body. She talks about the shift away from using embryonic stem cells and the practicality of using iPSCs for disease modeling and drug discovery.

Dr. Nolta also discusses the importance of matching human leukocyte antigen (HLA) types for stem cell therapies and the creation of cell banks containing pluripotent stem cell lines. She explains how these stem cells can be used for transplantation in individuals in need of stem cell therapies.

The conversation then delves into the ethical considerations and FDA approval process for stem cell therapies. Dr. Nolta emphasizes the importance of FDA-regulated clinical trials and the rigorous standards that need to be met.

Moving on to manufacturing stem cells, Dr. Nolta describes the process that takes place in Good Manufacturing Facilities (GMP). She explains the importance of maintaining sterility and the use of bioreactors in growing the cells. The cells are then delivered to the patient fresh, as freezing can compromise their quality and function.

Dr. Nolta discusses the California Umbilical Cord Blood Collection Program, which aims to increase the availability of diverse cord blood units in national inventory. She explains the different options for cord blood banking, including public and private banking.

The conversation covers various stem cell therapies, including bone marrow transplantation, gene therapy, and CAR T-cell therapy. Dr. Nolta highlights the success stories in treating genetic diseases and cancer using these therapies. She also touches on the use of cytokines and mesenchymal stem cells for modulating inflammation and promoting healing.

The hosts ask about the challenges of implementing AI in medicine and stem cell therapy. Dr. Nolta discusses the expense of obtaining whole genome sequences and the hesitation of insurance companies to cover these costs. She emphasizes the need for a better understanding of the causes of diseases to improve regenerative medicine.

Dr. Nolta concludes with advice for students interested in getting involved in regenerative medicine and stem cell research. She mentions the training programs and opportunities available and encourages students to stay curious and enthusiastic in their pursuit of scientific knowledge.

Overall, this episode provides an insightful and comprehensive overview of stem cells, regenerative medicine, and the potential future advancements in the field.

This presentation is a service of Discovering Academia, and all information presented is for commercial and informational purposes only. Discovering Academia provides no assurances as to the accuracy or completeness of the information presented and possesses no actual knowledge of any topic presented. Any opinions expressed in this presentation are solely attributed to each individual asserting the same and do not reflect the opinion of Discovering Academia.

Overall, this episode provides an insightful and comprehensive overview of stem cells, regenerative medicine, and the potential future advancements in the field.

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#020 - Laramie Taylor: What Influences Our Sexual and Romantic Relationships?

Join us for an engaging conversation with Laramie Taylor, Professor and Department Chair of Communication at UC Davis. With a keen focus on the intersection of media and society, Professor Taylor's research delves into the profound ways in which media shapes our lives within a social context.

In this captivating episode, we dive deep into the realm of the media and its influence on romantic relationships. Together, we explore the intricate dynamics of messaging and how it molds our perspectives on infidelity. Moreover, we unravel the impact of dating apps and their transformative effect on modern relationships. Professor Taylor's expertise helps us navigate through the digital landscape, as we analyze how these platforms shape our own perceived ranking within the dating pool.

In addition, we delve into the intriguing realm of biological factors influencing mate selection. Professor Taylor provides valuable insights into the potential effects of hormonal birth control on women and how these alterations in preferences can have broader societal implications.

Tune in as we explore the captivating interplay between biology, media, and the complexities of romantic relationships. Get ready to gain valuable insights into the influence of media messaging, our perspectives on infidelity, our own desirability, and the ever-evolving world of dating apps. Tune in to this thought-provoking episode and prepare to be enlightened by Professor Laramie Taylor's expertise and research.

Next Episode

#022 - Geoffrey Schladow: Exploring Lake Tahoe’s Ecosystem From Clarity to Microplastics

Join us for an exciting episode with Professor Geoff Schladow as we delve into the captivating world of Lake Tahoe's cutting-edge research.

As the director of the prestigious Tahoe Environmental Research Center, Professor Schladow unveils the groundbreaking studies taking place in this sanctuary. Lake Tahoe's unique environment attracts global attention and resources, driving research with profound, far-reaching impacts.

Our focus centers on Lake Tahoe's vital challenges – striking the perfect equilibrium between development and environmental preservation. We explore how the center raises awareness about human impact, addresses population growth, and confronts climate change head-on.

Hold on tight as we delve into the magic of watersheds and unravel the mysteries of eutrophication. But that's not all – prepare to be amazed by ingenious solutions like hypolimnetic oxygenation, sustaining the lake's ecosystem in remarkable ways.

In this captivating episode, we'll immerse ourselves in Lake Tahoe's intricate ecosystem and delve into the enthralling ongoing research at Clear Lake. From oxygen depletion to microplastics and water clarity, no stone is left unturned. We also explore the significance of Lake Tahoe being the clearest it has been in over 40 years and unveils the secrets behind Tahoe's mesmerizing blue appearance

Prepare to be inspired! Professor Geoff Schladow's passion and expertise will ignite your curiosity to join the mission of safeguarding our precious lakes and ecosystems making sure the breathtaking beauty of Lake Tahoe is preserved for generations.