Curious Cases

It was a dark and stormy night. A secret message arrived addressed to Rutherford & Fry from a mysterious woman called Heidi Daugh, who demanded to know: "Why do people like to be scared? For example, going on scary amusement park rides and watching horror movies that make you jump.”

What followed was an investigation, which would test our intrepid duo to their very limits. They explore the history of horror, starting with its literary origins in the Gothic fiction classic 'The Castle of Otranto'.

Adam challenges Hannah to watch a horror film without hiding behind a cushion. She quizzes horror scholar Mathias Clasen to find out why some people love the feeling of terror, whilst it leaves other cold.

Sociologist Margee Kerr and psychologist Claudia Hammond are also on hand to explore why scary movies are so powerful and popular. Then Rutherford and Fry investigate the more physical side of fear, when they delve into the history of roller coasters to investigate why we enjoy being scared.

Never ones to shy away from a challenge, the pair attempt to channel their inner adrenaline junkies with a trip on one the UK's scariest roller coasters at Thorpe Park.

David Poeppel from New York University studies the science of screaming, and we discover what makes screams uniquely terrifying. Plus, psychologist and broadcaster Claudia Hammond describes some early experiments which tested how fear affects our body.

This episode is a remake of two earlier broadcast episodes.

Producers: Fiona Roberts & Michelle Martin

Presenter: Adam Rutherford & Hannah Fry

First broadcast on BBC Radio 4 in February 2021.

Why does my heart not ache after exercise? asks listener Keith. Rutherford and Fry explore how and why heart muscle cells are special.

Dr Mitch Lomax is a sports scientist at the University of Portsmouth. She helps actual Olympic swimmers get faster. She explains how most of the muscles attached to our skeletons work: Tiny fibres use small-scale cellular energy, which, when all these fibres work in concert, turns into visible muscular movement. Mitch also explains how the dreaded Delayed Onset Muscle Soreness, or DOMS, can hit, taking a stair-wincing 48-72 hours to peak after exercise.

But skeletal muscles turn out to be quite different to heart muscles, as consultant cardiologist Dr Rohin Francis explains. Heart cells are more efficient and don't get fatigued like skeletal muscle cells. They are extremely energetic and 'just want to beat'. He also explains that the sensory feedback from the heart muscles is different too. They have a different sort of nerve supply, with fewer sensory nerves, so that there is less chance of pain signals being sent to the brain.

However, heart cells' incredible abilities are counterbalanced by one Achilles-like flaw: They cannot easily heal. Professor Sanjay Sinha is a British Heart Foundation (BHF) Senior Research Fellow and a Professor in Cardiovascular Regenerative Medicine at the University of Cambridge. His job is to fix broken hearts and he explains to Adam how new research into stem cells could be used to fix normally irreparable heart cells.

Presenters: Hannah Fry and Adam Rutherford

Producers: Jennifer Whyntie and Fiona Roberts

First broadcast on BBC Radio 4 in October 2021.

The world is full of colour! But, wonders listener Maya Crocombe, ‘how do we see colour and why are some people colour blind?’

Dr Rutherford and Professor Fry set out to understand how special light-sensitive cells in our eyes start the process of colour perception, why people sometimes have very different experiences of colour and whether, in the end, colour is really just ‘in our heads’.

Dr Gabriele Jordan from Newcastle University explains why lots of men struggle to discriminate between certain colours and why there were lots of complaints from colour-blind viewers when Wales played Ireland at rugby.

Professor Anya Hurlbert, also from Newcastle University, tackles the most divisive of internet images: The Dress! Did you see it as blue-black or yellow-gold? Anya explains why people see it so differently, and why our ability to compensate for available light is so useful.

Finally, Dr Mazviita Chirimuuta, a philosopher at the University of Edinburgh, gives us her take on what all this means: are colours real, or just in our minds?

If you want to see some of the images and activities referenced in the episode read on... To take the colour perception test which Hannah and Adam do in the epsiode, search for the 'Farnsworth Munsell Hue test' - you can do it online for free. To see the Dunstanborough Castle illusion as described in the episode, check out the Gallery section on the Curious Cases BBC website. To learn more about colour blindness, and for support and resources go to colourblindawareness.org

Producer: Ilan Goodman

First broadcast on BBC Radio 4 in March 2022.

Whilst watching a documentary about some poisonous frogs, Curio Janni in Amsterdam, started to wonder what would happen if a frog licked itself or another frog of the same species.

She asks Dr Adam Rutherford and Professor Hannah Fry to investigate whether an animal would react badly to a toxin it itself produces?

In essence 'can a venomous snake kill itself by biting itself?'

Of course the answer is complicated, but the sleuths know exactly who to ask.

Steve Backshall, award-winning wildlife explorer, best known for his BBC series 'Deadly 60'. Author of 'Venom – Poisonous Creatures in the Natural World'. Steve has been bitten, stung and spat at by a plethora of venomous creatures during his career. He also studied the first known venomous newt - the sharp-ribbed newt - a creature that has sharpened ribs that when it's under attack, it will squeeze its body force those ribs out through its skin, coating them in venom, which is then delivered into the mouth of an attacker.

Professor Nick Casewell, studies venomous snakes and their impact on humans. He works on treatments for snakebites at the Liverpool School of Hygiene and Tropical Medicine. Snakebites have a huge impact on communities in South Asia, Sub-Saharan Africa and South America. It's now been reinstated as one of the most serious neglected tropical diseases by the World Health Organisation. Traditional treatments - antivenins - can be expensive, difficult to access and don't always work - Nick is looking into alternative medicines to treat snakebite victims.

Dr. Ronald Jenner is Principal Researcher in the Comparative Venomics group at the Natural History Museum's Life Sciences, Invertebrates Division and co-wrote the book ‘Venom -the secrets of nature's deadliest weapon.’ He explains the evolutionary arms race between venomous predators and their prey and poisonous prey and their predators. He explains how resistance to venom has evolved and how venom has evolved to be more or less powerful over time, answering another Curio - Scott Probert's question on the evolution of venom.

Christie Wilcox wrote 'Venomous – How Earth’s Deadliest Creatures Mastered Biochemistry'. She studied the molecular basis of lionfish venom. Christie describes how venom and immunity to venom works at the molecular level.

Presenters: Adam Rutherford and Hannah Fry

Producer: Fiona Roberts

First broadcast on BBC Radio 4 in November 2021.

Why does human hair go grey and is it ever possible for it to go white overnight from shock?

Hannah and Adam explore why hair goes grey, how much stressful life events and a lack of sleep can speed up the process.

They hear from the pilot whose hair turned white after a flight where all 4 of his engines failed after flying through a volcanic ash cloud - was the shock responsible?

They also uncover new research which has shown it's possible for greying hair to return to its natural colour and ask if this finding could be exploited to uncover a cosmetic way to reverse hair greying?

Presenters: Hannah Fry and Adam Rutherford Producer: Pamela Rutherford

First broadcast on BBC Radio 4 in March 2022.