Episode 38 - Infinity Products | Massive Transfusion Protocols

03/18/25 • 37 min

Perfectly balanced, as all things should be. All that blood doesn’t just arrive when you snap your fingers together. The REALITY is you need the TIME and SPACE to thaw that frozen plasma and the strength of MIND to keep all the components in the right ratios. Only the chosen few with the POWER of transfusion medicine and the SOUL of the laboratory can direct the most immense of transfusions - the massive transfusion. Listen to this episode and maybe you can run the GAUNTLET of the MTP.

Timestamps:

0:53 - Get ready for MASSIVE. TRANSFUSION. PROTOCOL.
1:45 - What is an MTP?
4:10 - A bleedy example
7:11 - Activating the MTP
8:52 - Consent in MTPs
11:16 - MTP packs
12:27 - Crossing plasma groups
15:30 - 1:1:1 Transfusion
17:29 - Whole Blood Transfusion
19:49 - Acidosis
22:21 - Hypothermia
23:14 - Hypocalcaemia
25:12 - Resus Associated Coagulopathy
25:49 - DIC
26:58 - Trauma Induced Coagulopathy
29:19 - Summary of Resuscitative Endpoints
31:05 - Viscoelastic testing
33:12 - Factor Concentrates
34:55 - Take home messages

Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

Timestamps:

Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

Previous Episode

Episode 37 - In The Lab: Red Cell Matchmaking | Group and Hold, Antibody Screen, Crossmatch

It’s an early trip to the lab this season to explore exactly how we safely match the blood in the bank to the patient on the ward. Follow your trusty hand-labelled group-and-hold tube as we unpack what actually goes into blood grouping, antibody screening and the final hurdle, the crossmatch!

Timestamps

0:52 - Nick lives in squalor, surprising nobody
2:56 - The Group
4:22 - The Forward Group
6:53 - The Reverse Group
10:55 - The Antibody Screen
18:12 - DAT vs IAT
20:39 - The Crossmatch
25:08 - Anamnestic Antibody Responses
27:58 - Phenotyping
30:25 - Episode Summary

Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

Next Episode

Episode 39 - Tweaks and Tune-Ups | A Guide to Blood Product Modifications

Keen to augment your blood transfusion game but confused as to when, where and why? Join the Bloody Minded boffins as we cover all the major modifications to blood products you can order. More importantly, why you should and sometimes shouldn't bother ordering them. Have a sensible conversation with your blood bank after you listen to this episode.

Timestamps:

00:58 - How the blood bank actually works

04:03 - Aged Products

07:30 - Frozen Cells

10:32 - Transfusing the Bombay phenotype

12:10 - Leukodepletion

13:57 - CMV negative

19:17 - Irradiated units

19:52 - TA-GVHD

27:58 - HLA Matching

32:46 - Take home messages

Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au