Bloody Minded - Episode 12 - Haemolysis: Breaking it down! | Testing for Haemolysis

Episode 12 - Haemolysis: Breaking it down! | Testing for Haemolysis

08/13/24 • 28 min

Haemolysis? Do I really hapto send off more tests? This is reticulous! Now you know what a red cell is - lets learn about how they can break down. Join us as we explore what your boss actually wanted you to do when they asked for a haemolysis screen, and about Cale's deep seated distrust of hepatologists.
Timestamps
2:30 - Haemolysis - what is it (good for?)
7:58 - Reticulocytes? What a reticulous name for a cell
9:36 - LDH - Nick will talk about biochemistry here, I'm SORRY okay?
11:36 - Bilirubin feat. Gilbert - winner of the 2015 Triple J's Hottest 100
16:10 - Haptoglobin (with apologies to my anaesthetist friends)
20:32 - Who is DAT?
23:49 - Haemolysis screen recap - click here when med reg is impatient
27:35 - Take home messages!

Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

Previous Episode

Episode 11 - What is Blood ft. Erythrocytes | Haematopoiesis & Haematinics Overview

What is blood (Baby don't hurt me)? Rejoice as we escape the land of coagulation and look at some of the questions we have all asked during our medical training- what is blood? Does everybody have blood? Why is there so much of it on this floor? Who are you and how did you get in here? Join us as we we answer all these questions and more this episode with a focus on red cells.
Timestamps
1:33 - Blood - What is it (good for)?
3:49 - Differentiation of blood cells (my progenitors would be proud)
6:29 - Where did blood come from? Where did blood go? Where did you come from cotton blood Joe?
07:47- White cell summary is here. Basophils still a mystery.
10:30 - Finally the red cell talk I've been waiting for
12:07 - Four ingredients to make a red cell. Prep time 5 min, cleanup 120 days
13:26 - Iron (in more detail than anyone could possibly want)
16:34 - B12 and folate. Don't do nangs, kids (despite this bit here)
21:28 - MCV - Why haematologists care about cell size (I mean it's more about how you use it)
25:18 - Take home messages, predominantly nang based

Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

Next Episode

Episode 13 - In the Lab: Dr Coombs? Who is DAT? | Direct Coombs Test

“It’s Test. Coombs Test. And I like my erythrocytes shaken, not stirred.” Return the lab (where some of the Bloody Minded Crew truly belong) and uncover the secrets of the most important test in haemolysis - the Direct Antiglobulin Test. Learn to whisper its secrets and it can guide you to identifying the true culprit behind these broken red cells.
Timestamps:
0:57 - Coombs Noir
2:05 - Naming History
4:32 - DAT in the Lab
11:52 - Doing a DAT - Exam Version
14:35 - Eluates (Briefly)
15:45 - False Positives & Negatives
18:24 - When to DAT?
21:55 - Distilling the DAT - Interpretation
25:38 - DAT-Vanced Topics
29:24 - Takehome Points

Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au