This episode is about protein folding, specifically the protein folding problem that has pervaded biochemistry since 1960, when the first atomic-resolution protein structure was presented. First I will explain what proteins are, why they are important, what they are made of - proteins 101 - then begin unravelling the problem of how they fold. We will explore the motivations behind the problem and its greatest challenges. Finally we’ll consider the existing methods for determining protein structure, with particular focus on DeepMind’s AlphaFold, before finishing with the future of protein folding.
https://whatwedontknow.buzzsprout.com/
11/09/21 • 17 min
What We Don't Know - Protein folding
Transcript
Hello everyone, welcome to the seventh episode of ‘What We Don’t Know’, a podcast that explores the boundaries of human knowledge, investigating the unanswered questions and theories that unravel them at the frontiers of science. During this podcast I hope to get you interested in new areas of science, maths and technology, teaching you about existing concepts and igniting a curiosity for the things we have yet to know.
This episode is about protein folding, specifically the protei
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