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Unmasking COVID-19 - HIV in COVID-19

HIV in COVID-19

05/13/20 • 27 min

Unmasking COVID-19

In this episode, Dr. Pai answers questions specific to HIV in the context of COVID-19, including parallels between the two pandemics, repercussions of COVID-19 on patients with HIV and guidance for handling potential changes to antiretroviral regimens.

Questions:

From Peter Chin-Hong, MD, at the University of California, San Francisco:

"What are the parallels between the HIV and COVID-19 epidemic?"

"What lessons can we learn from the early response to HIV that can inform how we approach COVID-19?"

"Are HIV patients with COVID-19 doing worse? What information do we have?"

"What repercussions of COVID-19 will HIV patients have (mental illness, etc.)?"

From Jennifer Ross, PharmD, at the University of Iowa College of Pharmacy:

"Many antiretroviral agents (e.g., l lopinavir/ritonavir, boosted darunavir), are being evaluated in clinical trials or are prescribed for off-label use for the treatment or prevention of COVID-19. What additional considerations should be made when proposing a change in a patient’s antiretroviral regimen in the midst of COVID-19?"

We’d love to hear from you! Send your comments/questions to [email protected]. Be sure to check Healio.com/coronavirus for daily updates on the pandemic and follow us on Twitter @InfectDisNews and @GoHealio.

Disclosures: Pai reports serving on the advisory boards of Abbvie and Gilead Sciences.

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In this episode, Dr. Pai answers questions specific to HIV in the context of COVID-19, including parallels between the two pandemics, repercussions of COVID-19 on patients with HIV and guidance for handling potential changes to antiretroviral regimens.

Questions:

From Peter Chin-Hong, MD, at the University of California, San Francisco:

"What are the parallels between the HIV and COVID-19 epidemic?"

"What lessons can we learn from the early response to HIV that can inform how we approach COVID-19?"

"Are HIV patients with COVID-19 doing worse? What information do we have?"

"What repercussions of COVID-19 will HIV patients have (mental illness, etc.)?"

From Jennifer Ross, PharmD, at the University of Iowa College of Pharmacy:

"Many antiretroviral agents (e.g., l lopinavir/ritonavir, boosted darunavir), are being evaluated in clinical trials or are prescribed for off-label use for the treatment or prevention of COVID-19. What additional considerations should be made when proposing a change in a patient’s antiretroviral regimen in the midst of COVID-19?"

We’d love to hear from you! Send your comments/questions to [email protected]. Be sure to check Healio.com/coronavirus for daily updates on the pandemic and follow us on Twitter @InfectDisNews and @GoHealio.

Disclosures: Pai reports serving on the advisory boards of Abbvie and Gilead Sciences.

Previous Episode

undefined - A Mixed Bag

A Mixed Bag

This episode features questions regarding the use of masks, the use of steroids, universal PPE, antibody testing, convalescent plasma, COVID-19 in pets and whether hydroxychloroquine has any effect on the cytokine storm.

Questions:

From Gail D. Deyle, DSc, of the Brooke Army Medical Center, in San Antonio, Texas:

“The information available to the general public has ranged from masks do very little to help reduce the spread of the virus, to statements that if 80% of the population wore a mask, most transmission would be stopped. Consistent with current evidence, and distinct from fears of the general public competing with healthcare providers to purchase masks, what benefit do homemade and other masks provide? Is your family wearing masks?”

From Mike Putman, MD, of Feinberg School of Medicine at Northwestern University:

“I'd love to hear the panel talk about steroids.”

From Adam Cheifetz, MD, of Beth Israel Deaconess Medical Center:

“How contagious are carriers prior to being symptomatic and for how long after diagnosis are you still contagious?

“When will we see a serology test to determine if someone, ourselves included, have already had COVID-19?”

From Masoud Sakhaei, MD, of Baptist Health in Jacksonville, FL:

“Most likely, COVID-19 will be with us. Until we have a vaccine or cure, we do have to find a balance between livable society and avoidance of infection and fatality. We need a better universal PPE to be cheap and abundant for everybody to be able to go back to work and be protected.”

“We need universal screening to collect antibodies from recovered individuals in case somebody got sick. I’d like the panel’s opinion on this.”

From Scott Harris, MD, a retired cardiologist previously in private practice in Texas:

“Does the activity of hydroxychloroquine in reducing cytokine levels in vitro have a possible beneficial effect in blunting the cytokine storm?”

From Marcia Miller-Hjelle, PhD, of the University of Illinois College of Medicine at Peoria:

“Why have veterinarians not been brought into the mix of providing information and studies, such as are cats and dogs carriers of COVID-19? Hopefully, someone is testing this.”

From Stephen Hanauer, MD, of Northwestern University:

“We are planning a meeting in December, but faculty are concerned about recycling of the virus. Are there any predictions on what will happen when we return to socializing and winter returns?”

We’d love to hear from you! Send your comments/questions to mailto:[email protected]. Be sure to check Healio.com/coronavirus for daily updates on the pandemic and follow us on Twitter @InfectDisNews and @GoHealio.

Disclosures: Pai reports serving on the advisory boards of Abbvie and Gilead Sciences.

Next Episode

undefined - Diagnostic Testing for COVID-19

Diagnostic Testing for COVID-19

As the country prepares to reopen, rapid and effective testing remains “the need of the hour.” In this episode, Dr. Pai discusses diagnostic testing for COVID-19, including which populations to prioritize for testing, available modalities and new options.

Overview of symptoms 1:05

A look at testing modalities 3:34

Saliva samples for COVID-19 11:19

Antibody testing 13:03

Antigen testing 21:48

Nothing can replace clinical judgment 24:20

We’d love to hear from you! Send your comments/questions to [email protected]. Be sure to check Healio.com/coronavirus for daily updates on the pandemic and follow us on Twitter @InfectDisNews and @GoHealio.

Disclosures: Pai reports serving on the advisory boards of Abbvie and Gilead Sciences.

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