
Thyroid Talk Episode 6: Thyroid Hormone Replacement for Hypothyroidism: What are the options and how is treatment monitored?
05/03/22 • 28 min
Thyroid Talk with Dr. Angela Mazza
Recorded 4-15-22
SHOW NOTES EPISODE 6, 2022
Thyroid Hormone Replacement for Hypothyroidism:
What are the Options, and How is Treatment Monitored?
Host: Dr. Angela Mazza
Co-host: Dawn Sheffield
I’m Dr. Angela Mazza, a thyroid, endocrine, and metabolism specialist with a private practice in Central Florida. My goal for this podcast is to define and demystify the thyroid gland, and thyroid-related medical conditions. By providing information in an easy-to-understand format, we hope to help patients better understand the ways in which their bodies work, and to help them thrive. My goal is to help us live more fulfilling lives by taking control of our health, to feel our best.
I wanted to do this podcast to provide life-saving education and encourage folks to see a doctor in time to prevent or minimize damage. That’s deeply fulfilling. I enjoy helping folks understand how all aspects of their lives are tied to both thyroid and overall health.
In fact, this is why I went into endocrinology. It’s a medical art that combines science with the study of our lives—and all that they encompass.
To recap some of what we discussed in episode 6—not necessarily in this order:
· Why thyroid hormone is so important;
· The role, and types, of levothyroxine;
· The potential differences between various products;
· Hypothyroid (underactive); Hashimoto thyroiditis; monitoring;
· Thyroid hormone replacement goals and options; when to provide—and why;
· The role of T4 and T3 (see also episode 5 for additional information);
· Generic products; reverse T3; thyroid antibodies;
· What are fillers in medications?;
· Tablets, capsules, liquids—delivery systems;
· GI absorption and Hashimoto thyroiditis;
· The benefits of a reputable compounding pharmacy;
· Liothyronine vs. levothyroxine and their half-lives;
· Converting T4 effectively to T3—possible role of liothyronine;
· Forms of replacement thyroid hormones: synthetic, dessicated, compounded;
· Lab tests to monitor therapy for thyroid hormone replacement—and interpreting them;
· Following—or, tracking—lab results over tests and time;
· A medication perfect for one person may not be right for another; every person with hypothyroidism is unique, and so is their therapeutic plan.
I hope this discussion on thyroid hormone replacement therapy options was helpful, and that you will continue listening to this podcast. We’ll build on today’s foundation, and cover some topics I think you’ll find meaningful. We have many more interesting episodes and guests planned.
In our next episode we’ll cover micronutrients that are important for the thyroid.
We welcome your comments, show ideas, and questions for future episodes. Please send them to [email protected]
We may disclose your general location on air (the city or town, for example), but we will NOT read your name NOR your address on the show.
Don’t forget to ask your healthcare
Check out our YouTube channel - Dr. Angela Mazza, our website at Metabolic Center for Wellness, our FaceBook and our Instagram page.
Thyroid Talk with Dr. Angela Mazza
Recorded 4-15-22
SHOW NOTES EPISODE 6, 2022
Thyroid Hormone Replacement for Hypothyroidism:
What are the Options, and How is Treatment Monitored?
Host: Dr. Angela Mazza
Co-host: Dawn Sheffield
I’m Dr. Angela Mazza, a thyroid, endocrine, and metabolism specialist with a private practice in Central Florida. My goal for this podcast is to define and demystify the thyroid gland, and thyroid-related medical conditions. By providing information in an easy-to-understand format, we hope to help patients better understand the ways in which their bodies work, and to help them thrive. My goal is to help us live more fulfilling lives by taking control of our health, to feel our best.
I wanted to do this podcast to provide life-saving education and encourage folks to see a doctor in time to prevent or minimize damage. That’s deeply fulfilling. I enjoy helping folks understand how all aspects of their lives are tied to both thyroid and overall health.
In fact, this is why I went into endocrinology. It’s a medical art that combines science with the study of our lives—and all that they encompass.
To recap some of what we discussed in episode 6—not necessarily in this order:
· Why thyroid hormone is so important;
· The role, and types, of levothyroxine;
· The potential differences between various products;
· Hypothyroid (underactive); Hashimoto thyroiditis; monitoring;
· Thyroid hormone replacement goals and options; when to provide—and why;
· The role of T4 and T3 (see also episode 5 for additional information);
· Generic products; reverse T3; thyroid antibodies;
· What are fillers in medications?;
· Tablets, capsules, liquids—delivery systems;
· GI absorption and Hashimoto thyroiditis;
· The benefits of a reputable compounding pharmacy;
· Liothyronine vs. levothyroxine and their half-lives;
· Converting T4 effectively to T3—possible role of liothyronine;
· Forms of replacement thyroid hormones: synthetic, dessicated, compounded;
· Lab tests to monitor therapy for thyroid hormone replacement—and interpreting them;
· Following—or, tracking—lab results over tests and time;
· A medication perfect for one person may not be right for another; every person with hypothyroidism is unique, and so is their therapeutic plan.
I hope this discussion on thyroid hormone replacement therapy options was helpful, and that you will continue listening to this podcast. We’ll build on today’s foundation, and cover some topics I think you’ll find meaningful. We have many more interesting episodes and guests planned.
In our next episode we’ll cover micronutrients that are important for the thyroid.
We welcome your comments, show ideas, and questions for future episodes. Please send them to [email protected]
We may disclose your general location on air (the city or town, for example), but we will NOT read your name NOR your address on the show.
Don’t forget to ask your healthcare
Check out our YouTube channel - Dr. Angela Mazza, our website at Metabolic Center for Wellness, our FaceBook and our Instagram page.
Previous Episode

Thyroid Talk Episode 5: Lab Test Results: What do the Thyroid Numbers Mean?
Thyroid Talk with Dr. Angela Mazza, DO
Recorded 4-8-2022
SHOW NOTES EPISODE 5, 2022
Lab Test Results: What Do The Thyroid Numbers Mean?
Host: Dr. Angela Mazza
Co-host: Dawn Sheffield
I’m Dr. Angela Mazza, a thyroid, endocrine, and metabolism specialist with a private practice in Central Florida. My goal for this podcast is to define and demystify the thyroid gland, and thyroid-related medical conditions. By providing information in an easy-to-understand format, we hope to help patients better understand the ways in which their bodies work, and to help them thrive. My goal is to help us live more fulfilling lives by taking control of our health, to feel our best.
To recap some of what we discussed in episode 5—not necessarily in this order:
· Lab report numbers related to the thyroid—how they are understood; How numbers on a lab report may—or may not—correlate with what a patient is feeling or exhibiting. Why some patients seem to have good thyroid lab results but they don’t feel as good as their numbers look—the nuances of thyroid hormone physiology;
· The feedback loop—how it controls thyroid hormone levels;
· The difference between bound and unbound (or free) thyroid hormone levels;
· Basic thyroid physiology and the role of thyrotrophs, the hypothalamus, pituitary, Reverse T3, and TRH;
· TSH, releasing hormones, the thyroid gland, and TBG;
· Why the thyroid doesn’t just make the right amounts of bothT3 and T4 to start with;
· T4 and T3 have different half-lives. Half-lives defined—and what the half-lives are for T3 and T4;
· Euthyroid defined (and pronounced!);
· How to approach basic thyroid lab values like TSH, T4 and T3;
· The difference between T4 and T3.
I enjoy helping folks understand how their lives, their diets, stress management, sleep patterns—every aspect of their lives—are tied to both thyroid and overall health.
This has a lot to do with why I went into endocrinology. It’s a medical art that combines science with the study of our lives--and ALL that they encompass.
I hope you’ll continue listening to “Thyroid Talk with Dr. Angela Mazza.” We have many more interesting episodes and guests planned. We’ll build on today’s foundation, and cover some topics I think you’ll find meaningful.
In our next episode (episode 6) we’ll discuss the different thyroid hormone replacement therapies.
It’s great to know that we CAN impact our thyroid health!
We welcome your comments, show ideas, and questions for future episodes. Please send your thoughts to [email protected] We MAY disclose your general location on air (the city or town, for example), but we will NOT read your name NOR your address on the show.
Citations, references, and additional information:
Melmed, S., & Williams, R. H. (2011). Williams textbook of endocrinology (12th ed.). Philadelphia: Elsevier/Saunders.
Don’t forget to ask YOUR healthcare provider about any specific questions regarding your wellness. This podcast is meant for educational purposes only.
Copyright 2022 Dr. Angela Mazza DO. Thyroid Talk with Dr. Angela Mazza, DO. All rights reserved.
Check out our YouTube channel - Dr. Angela Mazza, our website at Metabolic Center for Wellness, our FaceBook and our Instagram page.
Next Episode

Thyroid Talk Episode 7: Micronutrients for Optimal Thyroid Performance
Thyroid Talk with Dr. Angela Mazza, DO
Recorded 5-13-2022
SHOW NOTES EPISODE 7
Micronutrients for Optimal Thyroid Performance
Host: Dr. Angela Mazza, DO
Co-host: Dawn Sheffield
I’m Dr. Angela Mazza, D.O., a thyroid, endocrine, and metabolism specialist with a private practice in Central Florida. My goal for this podcast is to define and demystify the thyroid gland, and thyroid-related medical conditions. By providing information in an easy-to-understand format, we hope to help patients better understand the ways in which their bodies work, and to help them thrive. My goal is to help us live more fulfilling lives by taking control of our health, to feel our best.
I wanted to do this podcast to provide life-saving education and encourage folks to see a doctor in time to prevent or minimize damage. That’s deeply fulfilling. I enjoy helping folks understand how all aspects of their lives are tied to both thyroid and overall health.
In fact, this is why I went into endocrinology. It’s a medical art that combines science with the study of our lives—and all that they encompass.
To recap some of what we discussed in episode 7—not necessarily in this order:
· What are micronutrients? (They’re not microbreweries, by the way!)
· Which micronutrients are important for optimal thyroid function?
· How “leaky gut” can impact supplement absorption—and options;
· Why iodine supplements should not be taken by everyone;
· The importance of medical review and supervision with supplements;
· How micronutrients can be measured;
· How intravenous infusions are good for persons for gut issues, and
· The importance of quality supplements.
· Best of all, we learned that we CAN impact our thyroid health!
I hope this discussion on micronutrients crucial to optimal thyroid performance was helpful, and that you will continue listening to this podcast. We’ll build on today’s foundation and cover some topics I think you’ll find meaningful. We have many more interesting episodes, and guests, planned.
In our next episode, episode 8, we’ll discuss Leaky Gut!
We welcome your comments, show ideas, and questions for future episodes. Please send them to [email protected] We may disclose your general location on air (the city or town, for example), but we will NOT read your name NOR your address on the show. We reserve the right to edit your input as necessary.
Don’t forget to ask your healthcare provider about any specific questions regarding your wellness. This podcast is meant for educational purposes only.
Copyright 2022 Dr. Angela Mazza DO. Thyroid Talk with Dr. Angela Mazza, DO. All rights reserved.
Check out our YouTube channel - Dr. Angela Mazza, our website at Metabolic Center for Wellness, our FaceBook and our Instagram page.
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