
TWiV 476: In ACOD1 we trust
01/14/18 • 104 min
Nels joins the TWiV team to talk about his work on genomic accordions in vaccinia virus, hepatitis B virus in a 439 year old mummy, and viral induction of energy synthesis by a long noncoding RNA.
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler
Guest: Nels Elde
Click arrow to play Download TWiV 476 (63 MB .mp3, 105 min) Subscribe (free): iTunes, RSS, email
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Links for this episode- ASV 2018: asv.org, asv2018.umd.edu
- TWiV is a must-listen (WaPo)
- More on poxvirus accordions (bioRxiv)
- HBV from a 439 year old mummy (PLoS Path)
- lncRNA promotes viral replication by inducing metabolism (Science)
- Making Data Visual
- Letters read on TWiV 476
Nels - Everyday Evolution Kathy - Paper-fold an ellipse Rich - Oxford Nanopore Technologies: YouTube channel; General technology; DNA sequencing; Sequencing singularity Dickson - Spiders that look like pelicans Alan - Guessing pool for China Spacelab reentry Vincent - How to take a picture of the stealth bomber over the rose bowl
Listener PicksGretchen - The Bearded Lady Project
Intro music is by Ronald Jenkees.
Send your virology questions and comments to [email protected]
Nels joins the TWiV team to talk about his work on genomic accordions in vaccinia virus, hepatitis B virus in a 439 year old mummy, and viral induction of energy synthesis by a long noncoding RNA.
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler
Guest: Nels Elde
Click arrow to play Download TWiV 476 (63 MB .mp3, 105 min) Subscribe (free): iTunes, RSS, email
Become a patron of TWiV!
Links for this episode- ASV 2018: asv.org, asv2018.umd.edu
- TWiV is a must-listen (WaPo)
- More on poxvirus accordions (bioRxiv)
- HBV from a 439 year old mummy (PLoS Path)
- lncRNA promotes viral replication by inducing metabolism (Science)
- Making Data Visual
- Letters read on TWiV 476
Nels - Everyday Evolution Kathy - Paper-fold an ellipse Rich - Oxford Nanopore Technologies: YouTube channel; General technology; DNA sequencing; Sequencing singularity Dickson - Spiders that look like pelicans Alan - Guessing pool for China Spacelab reentry Vincent - How to take a picture of the stealth bomber over the rose bowl
Listener PicksGretchen - The Bearded Lady Project
Intro music is by Ronald Jenkees.
Send your virology questions and comments to [email protected]
Previous Episode

TWiV 475: Everything is viral
In the first episode for 2018, the TWiV team reviews the amazing virology stories of 2017.
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler
Become a patron of TWiV!
Links for this episode- ASV 2018: asv.org, asv2018.umd.edu
- Virology stories of 2017 - in no particular order
- A virologist in space - TWiV 444
- Cool things viruses do: Astrovirus capsids are enterotoxins TWiV 423; giant Klosneuviruses encode lots of stuff for translation TWiV 437; Giant Noumeaviruses quickly make the nucleus temporarily leaky TWiV 440
- TWiV 438 Drs. TWiV go to Washington and the March for Science
- Unexpected stuff: TWiV 451 Expectorate the unexpected; TWiV 470 Just a passing phage; TWiV 456 Be careful of canons; TWiV 455 Pork and genes; TWiV 432 gamete fusion protein from viruses
- TWiV 443 On a leaf no one can hear you scream. The puppet master.
- TWiV 448 Mavis the structure maven
- Viruses are us: TWiV 472 Riddle of the skinks; TWiV 439 The purloined envelope; TWiV 434 Live long and pupate
- Antiviral RNA: TWiV 433 Poops viruses and worms; TWiV 449 The sound of non-silencing; TWiV 450 Ben tenOever and RNA out
- Viruses as tools: TWiV 461 Gotta trace them all
- Flaviviruses: TWiV 473, 471, 468; 458; 454; 451; 432; 430; 429; 426
- NSF survey of earned doctorates
- Letters read on TWiV 475
Kathy - Voyager recording and book Rich - David Sheldrick Wildlife Trust (Maktao) Dickson - Global Croplands Map Alan - The Great Influenza one day at a time Vincent - The Doomsday Machine by Daniel Ellsberg
Listener PicksMark - Science Moms and Science of HIV Andy - Ask Me Anything Steve - Critical Attitude in Medicine
Intro music is by
Next Episode

TWiV 477: Raiders of the lost Arc
The TWiVodrome explains how a gag-like protein from a retrotransposon forms virus-like particles that carry mRNA within vesicles across the synapse.
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler
Become a patron of TWiV!
Links for this episode- ASV 2018: asv.org, asv2018.umd.edu
- Arc virus-like particles transport RNA across the synapse (mammalian, Drosophila)
- Chemical synapse (Wikipedia)
- 2 minute video on the neuron
- Image credit
- Letters read on TWiV 477
Kathy - Ice cliffs form over the weekend Rich - The Courage To Invent: A NASA Roboticist Tells Her Story (Ayanna Howard) Dickson - 2017 Was One of the Hottest Years on Record Alan - Experimenter gender and replicability Vincent - Set Your Autocorrect to Change 'Guys' to 'Folks'
Listener PicksAsal - 100 million chickens with avian flu Mark - Dr. Tatiana's Sex Advice to All Creation
Intro music is by Ronald Jenkees.
Send your virology questions and comments to [email protected]
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