TWiV 1126: Clinical update with Dr. Daniel Griffin
06/29/24 • 39 min
1 Listener
In his weekly clinical update, Dr. Griffin discusses RSV vaccination recommendations and revisions to guidelines before reviewing the recent statistics on SARS-CoV-2 infection, data suggesting that individuals with high HLA-DQA2 expression (MHC class II) are better at preventing the onset of a sustained viral infection, how moderate coffee intake can reduce risk of COVID-19 severity but cannabis use resulted in more severe disease but reduced risk of mortality, where to find PEMGARDA, if statin use prevented severe COVID-19, the benefit of administering nirmatrelvir and ritonavir after 5 days, convalescent plasma, what do when healthcare workers succumb to SARS-CoV-2 infection, if fecal microbiota transplants aid in recovery from COVID-19, and the definition of characteristics and clinical patterns for the diagnosis of long COVID.
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Become a patron of TWiV!
Links for this episode- CDC ACIP for RSV (CDC)
- This respiratory virus season everyone age 75 and older receive the RSV vaccine (CDC Newsroom)
- Revised RSV vaccine recommendations (CIDRAP)
- COVID-19 national trend (CDC)
- COVID-19 deaths (CDC)
- Local and systemic response dynamics to SARS-CoV-2 infection (Nature)
- Drink more coffee, reduces risk for SARS-C0V-2 infection (Cell & Bioscience)
- Cannabis, tobacco...smoking in general NOT good for preventing COVID-19 (JAMA Network OPEN)
- Do older versions of the COVID-19 vaccine still provide any protection (JAMA Internal Medicine)
- Where to get pemgarda (Pemgarda)
- CDC Quarantine guidelines (CDC)
- Early phase of SARs-CoV-2 infection (COVID.gov)
- NIH COVID-19 treatment guidelines (NIH)
- Infectious Disease Society guidelines for treatment and management (ID Society)
- Adjuvant statin therapy reduces SARS-CoV-2 mortality (American Journal of Medicine)
- Nirmatrelvir and ritonavir beyond 5 days of symptom onset improved the multiple organ dysfunction in severe COVID-19 patient (BMC Infectious Disease)
- Molnupiravir safety and efficacy (JMV)
- Convalescent plasma recommendation for immunocompromised (ID Society)
- What do when your heathcare provider is infected with SARS-CoV-2 (CDC)
- Managing healthcare staffing shortages (CDC)
- Steroids,
In his weekly clinical update, Dr. Griffin discusses RSV vaccination recommendations and revisions to guidelines before reviewing the recent statistics on SARS-CoV-2 infection, data suggesting that individuals with high HLA-DQA2 expression (MHC class II) are better at preventing the onset of a sustained viral infection, how moderate coffee intake can reduce risk of COVID-19 severity but cannabis use resulted in more severe disease but reduced risk of mortality, where to find PEMGARDA, if statin use prevented severe COVID-19, the benefit of administering nirmatrelvir and ritonavir after 5 days, convalescent plasma, what do when healthcare workers succumb to SARS-CoV-2 infection, if fecal microbiota transplants aid in recovery from COVID-19, and the definition of characteristics and clinical patterns for the diagnosis of long COVID.
Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email
Become a patron of TWiV!
Links for this episode- CDC ACIP for RSV (CDC)
- This respiratory virus season everyone age 75 and older receive the RSV vaccine (CDC Newsroom)
- Revised RSV vaccine recommendations (CIDRAP)
- COVID-19 national trend (CDC)
- COVID-19 deaths (CDC)
- Local and systemic response dynamics to SARS-CoV-2 infection (Nature)
- Drink more coffee, reduces risk for SARS-C0V-2 infection (Cell & Bioscience)
- Cannabis, tobacco...smoking in general NOT good for preventing COVID-19 (JAMA Network OPEN)
- Do older versions of the COVID-19 vaccine still provide any protection (JAMA Internal Medicine)
- Where to get pemgarda (Pemgarda)
- CDC Quarantine guidelines (CDC)
- Early phase of SARs-CoV-2 infection (COVID.gov)
- NIH COVID-19 treatment guidelines (NIH)
- Infectious Disease Society guidelines for treatment and management (ID Society)
- Adjuvant statin therapy reduces SARS-CoV-2 mortality (American Journal of Medicine)
- Nirmatrelvir and ritonavir beyond 5 days of symptom onset improved the multiple organ dysfunction in severe COVID-19 patient (BMC Infectious Disease)
- Molnupiravir safety and efficacy (JMV)
- Convalescent plasma recommendation for immunocompromised (ID Society)
- What do when your heathcare provider is infected with SARS-CoV-2 (CDC)
- Managing healthcare staffing shortages (CDC)
- Steroids,
Previous Episode
TWiV 1125: Can pig flu viruses go viral?
TWiV reviews criticism of NIAID monkeypox virus experiments by House Republicans, spread of wild poliovirus across Afghanistan and Pakistan, plan to overhaul NIH by House lawmakers, and the potential pandemic risk of circulating swine H1N2 influenza viruses.
Hosts: Vincent Racaniello, Dickson Despommier, Brianne Barker, and Angela Mingarelli
Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email
Become a patron of TWiV!
Links for this episode- MicrobeTV Discord Server
- 2024 International HBV Meeting
- House Republicans fault NIH for evasive answers on monkeypox virus study (Science)
- Report on MPX experiments at NIAID (pdf)
- Wild poliovirus spreads across Pakistan and Afghanistan (Science)
- Plan to overhaul NIH (Science)
- Reforming NIH (pdf)
- Potential pandemic risk of circulating swine H1N2 influenza viruses (Nat Comm)
- Timestamps by Jolene. Thanks!
Angela – Staring at the Sun — close-up images from space rewrite solar science Brianne – Water frost detected on Mars Volcanos Dickson – Best view yet of the Crab Nebula Vincent – Will Your Tattoo Give You Cancer: Probably Not...but Maybe?
Listener PicksJessica – Manchurian plague
Intro music is by Ronald Jenkees
Send your virology questions and comments to [email protected]
Content in this podcast should not be construed as medical advice.
Next Episode
TWiV 1127: Giving prions the (zinc) finger
TWiV discusses secret anti-vax campaign run by Pentagon to undermine China during pandemic, NY governor’s subways mask ban proposal, Colorado bat facility sparks outbreak fears, House budget billls suggest ban on gain of function research, evolution of STAT2 resistance to flavivirus NS5, and brainwide silencing of prion protein by AAV-mediated delivery of an epigenetic editor.
Hosts: Vincent Racaniello, Dickson Despommier, and Alan Dove
Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email
Become a patron of TWiV!
Links for this episode- MicrobeTV Discord Server
- Pentagan anti-vac campaign to undermine China (Reuters)
- NY governor subway mask ban (AP News)
- Colorado bat facility sparks outbreak fears (Science)
- House NIH budget bans gain of function research (Science)
- Evolution of STAT2 resistance to flavivirus NS5 (Nat Commun)
- Brainwide silencing of prion protein by AAV delivered epigenetic editor (Science)
- Letters read on TWiV 1127
- Timestamps by Jolene. Thanks!
Dickson – Mars Odyssey Orbiter is about to make its 100,000th orbit Alan – Local animal shelters and “kitten season.” Vincent – Supreme Court allows cities to ban homeless people sleeping outside, even when shelter space is lacking
Listener PicksBlog design – Trump vows to defund schools requiring vaccines for students Jon – Detections of highly pathogenic avian influenza in mammals
Intro music is by Ronald Jenkees
Send your virology questions and comments to [email protected]
Content in this podcast should not be construed as medical advice.
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