TWiV 1124: Clinical update with Dr. Daniel Griffin
06/22/24 • 40 min
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In his weekly clinical update, Dr. Griffin reviews the recent statistics on SARS-CoV-2 infection, before discussing methods for sterilizing filtering facepieces, an update to the fall COVID boosters, the emergency use application of a pre-exposure prophylactic and where to find it and drug interaction database, convalescent plasma, the effectiveness of the monoclonal antibody sotrovimab against Omicron variants, what to do when healthcare workers succumb to SARS-CoV-2 infection, the need for better nursing resources, how survivors of COVID-19-associated ARDS exhibited sustained elevation in endothelial dysfunction biomarkers, correlating with the severity of impaired gas exchange, reactivation of latent CMV as a consequence of a SARS-CoV-2 infection, identification of variables that might impact or predict a person’s time to recovery from an acute SARS-CoV-2 infection and if COVID-19 patients really have olfactory dysfunction more often than normally smelling individuals.
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Links for this episode- COVID-19 national trend (CDC)
- COVID-19 deaths (CDC)
- Comparison of methods for sterilizing filtering facepiece respirators (American Journal of Infection Control)
- Booster update already! KP.2 of JN.1-lineage (FDA)
- EUA for pemgarda (FDA)
- Where to get pemgarda (Pemgarda)
- CDC Quarantine guidelines (CDC)
- Early phase of SARs-CoV-2 infection (COVID.gov)
- NIH COVID-19 treatment guidelines (NIH)
- Infectious Disease Society guidelines for treatment and management (ID Society)
- Drug interaction checker (University of Liverpool)
- Molnupiravir safety and efficacy (JMV)
- Convalescent plasma recommendation for immunocompromised (ID Society)
- Revisiting monoclonal antibody therapy, sotrovimab for treatment during Omicron BA.2 and BA.5 (Infection)
- What do when your healthcare provider is infected with SARS-CoV-2 (CDC)
- Managing healthcare staffing shortages (CDC)
- Steroids,dexamethasone at the right time (OFID)
- Anticoagulation guidelines (hematology.org)
- Hospital nurse staffing variation & COVID-19 (International Journal of Nursing Studies)
- Endothelial dysfunction and persistent inflammation severe post-COVID-19 (BMC Medicine)
- Prevalence and risk for
In his weekly clinical update, Dr. Griffin reviews the recent statistics on SARS-CoV-2 infection, before discussing methods for sterilizing filtering facepieces, an update to the fall COVID boosters, the emergency use application of a pre-exposure prophylactic and where to find it and drug interaction database, convalescent plasma, the effectiveness of the monoclonal antibody sotrovimab against Omicron variants, what to do when healthcare workers succumb to SARS-CoV-2 infection, the need for better nursing resources, how survivors of COVID-19-associated ARDS exhibited sustained elevation in endothelial dysfunction biomarkers, correlating with the severity of impaired gas exchange, reactivation of latent CMV as a consequence of a SARS-CoV-2 infection, identification of variables that might impact or predict a person’s time to recovery from an acute SARS-CoV-2 infection and if COVID-19 patients really have olfactory dysfunction more often than normally smelling individuals.
Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email
Become a patron of TWiV!
Links for this episode- COVID-19 national trend (CDC)
- COVID-19 deaths (CDC)
- Comparison of methods for sterilizing filtering facepiece respirators (American Journal of Infection Control)
- Booster update already! KP.2 of JN.1-lineage (FDA)
- EUA for pemgarda (FDA)
- Where to get pemgarda (Pemgarda)
- CDC Quarantine guidelines (CDC)
- Early phase of SARs-CoV-2 infection (COVID.gov)
- NIH COVID-19 treatment guidelines (NIH)
- Infectious Disease Society guidelines for treatment and management (ID Society)
- Drug interaction checker (University of Liverpool)
- Molnupiravir safety and efficacy (JMV)
- Convalescent plasma recommendation for immunocompromised (ID Society)
- Revisiting monoclonal antibody therapy, sotrovimab for treatment during Omicron BA.2 and BA.5 (Infection)
- What do when your healthcare provider is infected with SARS-CoV-2 (CDC)
- Managing healthcare staffing shortages (CDC)
- Steroids,dexamethasone at the right time (OFID)
- Anticoagulation guidelines (hematology.org)
- Hospital nurse staffing variation & COVID-19 (International Journal of Nursing Studies)
- Endothelial dysfunction and persistent inflammation severe post-COVID-19 (BMC Medicine)
- Prevalence and risk for
Previous Episode
TWiV 1123: Europic 2024 in Jyväskylä, Finland
Vincent travels to Europic 2024 in Jyväskylä, Finland to speak with Tapani Hovi and Caroline Tapparel about their careers and their research on enteroviruses and elimination of poliomyelitis.
Host: Vincent Racaniello
Guests: Tapani Hovi and Caroline Tapparel
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Become a patron of TWiV!
Links for this episode- Survival of influenza virus on banknotes (Appl Environ Micro)
- Variant EV-A71 in immunosuppressed patient (Cell Rep)
- Rhinoviruses and respiratory enteroviruses (Viruses)
- Isolation of poliovirus in mouse cells producing Pvr (J Clin Micro)
- Outbreak of paralytic poliomyelitis in Finland (Lancet)
- Role of environmental poliovirus surveillance in global polio eradication (Epi Infect)
- Timestamps by Jolene. Thanks!
Intro music is by Ronald Jenkees
Send your virology questions and comments to [email protected]
Content in this podcast should not be construed as medical advice.
Next Episode
TWiV 1125: Can pig flu viruses go viral?
TWiV reviews criticism of NIAID monkeypox virus experiments by House Republicans, spread of wild poliovirus across Afghanistan and Pakistan, plan to overhaul NIH by House lawmakers, and the potential pandemic risk of circulating swine H1N2 influenza viruses.
Hosts: Vincent Racaniello, Dickson Despommier, Brianne Barker, and Angela Mingarelli
Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email
Become a patron of TWiV!
Links for this episode- MicrobeTV Discord Server
- 2024 International HBV Meeting
- House Republicans fault NIH for evasive answers on monkeypox virus study (Science)
- Report on MPX experiments at NIAID (pdf)
- Wild poliovirus spreads across Pakistan and Afghanistan (Science)
- Plan to overhaul NIH (Science)
- Reforming NIH (pdf)
- Potential pandemic risk of circulating swine H1N2 influenza viruses (Nat Comm)
- Timestamps by Jolene. Thanks!
Angela – Staring at the Sun — close-up images from space rewrite solar science Brianne – Water frost detected on Mars Volcanos Dickson – Best view yet of the Crab Nebula Vincent – Will Your Tattoo Give You Cancer: Probably Not...but Maybe?
Listener PicksJessica – Manchurian plague
Intro music is by Ronald Jenkees
Send your virology questions and comments to [email protected]
Content in this podcast should not be construed as medical advice.
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