
TWiV 1072: Clinical update with Dr. Daniel Griffin
12/23/23 • 38 min
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In his weekly clinical update Dr. Griffin discusses the annual economic burden of respiratory syncytial virus in adults in the US, recombinant or standard-dose influenza vaccine in adults under 65 years of age, maternal vaccine effectiveness against influenza-associated hospitalizations and emergency department visits in iInfants, influenza positive tests reported to CDC by US clinical laboratories, update on COVID-19, risk of severe maternal morbidity associated with SARS-CoV-2 infection during pregnancy, COVID-19 rapid antigen tests with self-collected vs health care worker–collected nasal and throat swab specimens, optimal timing of nirmatrelvir/ritonavir treatment after COVID-19 symptom onset or diagnosis: target trial emulation, long-term outcomes following hospital admission for COVID-19 versus seasonal influenza: a cohort study, and risk of arrhythmias following COVID-19: nationwide self-controlled case series and matched cohort study.
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Become a patron of TWiV!
Links for this episode- RSV economic burden, US (J Inf Dis)
- Recombinant or standard dose influenza vaccine (NEJM)
- Maternal vaccine effectiveness against influenza in Infants (JAMA Ped)
- Weekly influenza surveillance report (MMWR)
- COVID data tracker (hospital admissions, national trend)
- Risk of severe maternal morbidity associated with SARS-CoV-2 infection (J Inf Dis)
- COVID-19 rapid antigen tests with nasal and throat swab specimens (JAMA Net Open)
- Optimal timing of nirmatrelvir/ritonavir (Nat Comm)
- Long-term outcomes following hospital admission for COVID-19 vs influenza (Lancet)
- Contribute to our MicrobeTV fundraiser at PWB
- Letters read on TWiV 1072
- Dr. Griffin’s COVID treatment summary (pdf)
- Timestamps by Jolene. Thanks!
Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to [email protected]
In his weekly clinical update Dr. Griffin discusses the annual economic burden of respiratory syncytial virus in adults in the US, recombinant or standard-dose influenza vaccine in adults under 65 years of age, maternal vaccine effectiveness against influenza-associated hospitalizations and emergency department visits in iInfants, influenza positive tests reported to CDC by US clinical laboratories, update on COVID-19, risk of severe maternal morbidity associated with SARS-CoV-2 infection during pregnancy, COVID-19 rapid antigen tests with self-collected vs health care worker–collected nasal and throat swab specimens, optimal timing of nirmatrelvir/ritonavir treatment after COVID-19 symptom onset or diagnosis: target trial emulation, long-term outcomes following hospital admission for COVID-19 versus seasonal influenza: a cohort study, and risk of arrhythmias following COVID-19: nationwide self-controlled case series and matched cohort study.
Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email
Become a patron of TWiV!
Links for this episode- RSV economic burden, US (J Inf Dis)
- Recombinant or standard dose influenza vaccine (NEJM)
- Maternal vaccine effectiveness against influenza in Infants (JAMA Ped)
- Weekly influenza surveillance report (MMWR)
- COVID data tracker (hospital admissions, national trend)
- Risk of severe maternal morbidity associated with SARS-CoV-2 infection (J Inf Dis)
- COVID-19 rapid antigen tests with nasal and throat swab specimens (JAMA Net Open)
- Optimal timing of nirmatrelvir/ritonavir (Nat Comm)
- Long-term outcomes following hospital admission for COVID-19 vs influenza (Lancet)
- Contribute to our MicrobeTV fundraiser at PWB
- Letters read on TWiV 1072
- Dr. Griffin’s COVID treatment summary (pdf)
- Timestamps by Jolene. Thanks!
Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to [email protected]
Previous Episode

TWiV 1071: Giant viruses and virophages with Matthias Fischer
Vincent visits the Max Planck Institute for Medical Research in Heidelberg, Germany to speak with Matthias Fischer about his career and his research on giant viruses, virophages, and their protist hosts.
Host: Vincent Racaniello
Guest: Matthias Fischer
Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email
Become a patron of TWiV!
Links for this episode- MicrobeTV Discord Server
- MicrobeTV store at Cafepress
- Research assistant position in Rosenfeld Lab CBER/FDA (pdf)
- C. roenbergensis giant virus (PNAS)
- Virophage at origin of large DNA transposons (Science)
- Host genome integration and giant virus-induced reactivation of virophage mavirus (Nature)
- Invasion of protist genomes by DNA viruses (PNAS)
- Timestamps by Jolene. Thanks!
Intro music is by Ronald Jenkees
Send your virology questions and comments to [email protected]
Next Episode

TWiV 1073: Taming the shrew and barring Epstein-Barr virus
TWiV explains a study showing that ost traits shape virome composition and virus transmission in wild bats, rodents, and shrews, and development of a gB nanoparticle vaccine that elicits a protective neutralizing antibody response against Epstein-Barr virus.
Hosts: Vincent Racaniello, Dickson Despommier, and Kathy Spindler
Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email
Become a patron of TWiV!
Links for this episode- MicrobeTV Discord Server
- MicrobeTV store at Cafepress
- Become a member of ASV (asv.org)
- Research assistant position in Rosenfeld Lab CBER/FDA (pdf)
- The New City by Dickson Despommier
- Brett Lindenbach passes (Yale Medicine)
- Virome of small mammals (Cell)
- Epstein-Barr virus nanoparticle vaccine (Cell Host Micr)
- Letters read on TWiV 1073
- Timestamps by Jolene. Thanks!
Dickson – Summary of Global Climate Action at COP 28 and Notable Deaths 2023: Music Kathy – Two APODS Winter solstice, 183 Days in the Sun and the Same color illusion Vincent – The American Academy of Microbiology discusses gain-of-function research of concern (GOFROC) and enhanced potential pandemic pathogens (ePPP)
Listener PicksGregory – Climate Change – A revised prediction – Steven Chu John – Detergent packs are kinda wishy-washy (Technology Connections)
Intro music is by Ronald Jenkees
Send your virology questions and comments to [email protected]
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