TWiV 829: Antiviral and cytotoxically empowered for COVID-19

A TWiV duo reviews how SARS-CoV-2 attacks the olfactory mucosa but spares the olfactory bulb, vaccination with BNT162b2 induces virus-specific stem cell memory T cells, and development of an oral protease inhibitor for the treatment of COVID-19.

Hosts: Vincent Racaniello and Brianne Barker

Subscribe (free): iTunes, Google Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

• How SARS-CoV-2 attacks olfactory mucosa (Cell)
• SARS-CoV-2-specific stem cell memory T cells after mRNA vaccine (Sci Immunol)
• Oral SARS-CoV-2 protease inhibitor (Science)
• Paxlovid phase 2/3 trial preliminary results (Pfizer)
• Letters read on TWiV 829
• Timestamps by Jolene. Thanks!

Weekly Picks

Brianne – Coronavirus Neutralizing Antibodies and mRNA Vaccine Video Vincent – MHC restriction of cytotoxic T cell lysis (Nobel description)

Listener Picks

Lisa – Shall Furnish Medicine Bistra – Saving the World by Julia Alvarez

Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]