
TWiP 182: Super spreaders of science
04/11/20 • 74 min
Dickson, Daniel and Vincent solve the case of the Ugandan Volunteer With Morning Bites and discuss integration of HIV-1 into the Schistosome genome, with a sprinkling of COVID-19 throughout.
Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin
Subscribe (free): iTunes, Google Podcasts, RSS, email
Links for this episode- PWB social media: Facebook, Instagram, Twitter
- Daniel on TWiV
- HIV-1 integration into Schistosome genome (PLoS Path)
- Image from John Southall's Treatise of Buggs, 1730.
- Letters read on TWiP 182
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Case Study for TWiP 18260 yo female comes in with husband, grew up in Lima Peru. Having issue had when child, would get itchiness around anus, mother would have her eat pumpkin seeds. Every 2-3 weeks wakes up with severe itching. Put in q-tip and extracted something, has video of it. ONP stool cultures negative. Referred to Daniel. Negative medical history, no allergies, no surgeries, no medications. Does travel, mainly to Uganda. HIV negative, no toxic habits. Husband reports no symptoms. Has children/grandchildren.
Send your case diagnosis, questions and comments to [email protected]
Music by Ronald Jenkees
Dickson, Daniel and Vincent solve the case of the Ugandan Volunteer With Morning Bites and discuss integration of HIV-1 into the Schistosome genome, with a sprinkling of COVID-19 throughout.
Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin
Subscribe (free): iTunes, Google Podcasts, RSS, email
Links for this episode- PWB social media: Facebook, Instagram, Twitter
- Daniel on TWiV
- HIV-1 integration into Schistosome genome (PLoS Path)
- Image from John Southall's Treatise of Buggs, 1730.
- Letters read on TWiP 182
Become a patron of TWiP.
Case Study for TWiP 18260 yo female comes in with husband, grew up in Lima Peru. Having issue had when child, would get itchiness around anus, mother would have her eat pumpkin seeds. Every 2-3 weeks wakes up with severe itching. Put in q-tip and extracted something, has video of it. ONP stool cultures negative. Referred to Daniel. Negative medical history, no allergies, no surgeries, no medications. Does travel, mainly to Uganda. HIV negative, no toxic habits. Husband reports no symptoms. Has children/grandchildren.
Send your case diagnosis, questions and comments to [email protected]
Music by Ronald Jenkees
Previous Episode

TWiP 181: Daniel's drive-through
Dickson, Daniel and Vincent solve the case of the Two Volunteers With Watery Diarrhea, discuss diagnosis of SARS-CoV-2 in the New York area, and reveal an approach to preventing honeybee colony collapse by imbuing their gut bacteria with the ability to produce antiviral and antiparasite double-stranded RNAs.
Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin
Subscribe (free): iTunes, Google Podcasts, RSS, email
Links for this episode- PWB social media: Facebook, Instagram, Twitter
- Daniel on TWiV Special
- Engineered symbionts limit honeybee pathogens (Science)
- Letters read on TWiP 181
Become a patron of TWiP.
Case Study for TWiP 181Risks of being helpful. Volunteer from previous case. Diarrhea is gone, now has second issue. Since coming to Uganda noticing on waking in AM often has series of 1 cm red raised lesions in a line, 3-4, on torso. Swollen and itchy. New ones in the AM. Manager says welcome to Uganda. They move out of room, leave bedding behind. Lesions stop. What is going on and when can they move back into room?
Send your case diagnosis, questions and comments to [email protected]
Music by Ronald Jenkees
Next Episode

TWiP 183: When they dry they die
Dickson, Daniel and Vincent solve the case of the Female with Itchy Anus, and reveal the structure of a roundworm membrane protein involved in digestion of nutrients.
Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin
Subscribe (free): iTunes, Google Podcasts, RSS, email
Links for this episode- Structure of roundworm digestive complex (PLoS Path)
- Hero: Dr. Anthony Fauci
- Fauci Pharmacy (TWiV 219)
- Letters read on TWiP 183
Become a patron of TWiP.
Case Study for TWiP 18370 yo male. Returns with wife from safari in S. Africa. Reports suffering from 2 weeks watery diarrhea. Severe water shortage in S. Africa, limited washing water, hand sanitizers to clean hands so problem with hand hygiene. 5 days after arrival he and wife have water diarrhea, 12 per day, nauseated, abdominal cramping. Ab no effect. Stool culture, ONP, negative. Healthy, no past med/surg, no allergies, nothing runs in family. Stool sent off for ONP acid fast stain, also GI PCR panel. Prompts treatment for 7 days trimethoprim sulfamethoxazole, resolves.
Send your case diagnosis, questions and comments to [email protected]
Music by Ronald Jenkees
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