
#7 - Joseph Baur - NAD, NMN, & NR - A Deep Dive Into NAD & It's Precursors w/ a Leading NAD Researcher
07/03/20 • 27 min
If you're confused about NAD and it's precursors then this is the podcast for you. Dr. Joseph Baur, an Associate Professor of Physiology from University of Pennsylvania, is a leading NAD researcher. His lab currently studies metabolic and signaling pathways by which nutrient intake can influence longevity, with a particular emphasis on NAD and mTOR.
In this interview Joseph breaks down all the questions I've had (and there's a lot) about the miracle molecule, NAD. Joseph helps me to understand why it's such an important molecule, how one can boost NAD levels, and what the data tells us about the different NAD precursors, NMN & NR.
As you may or not know there is quite a bit of debate about which NAD precursors work best, and if they even work at all to boost NAD levels in a way that will extend lifespan in humans. It was an absolute pleasure to have a non biased guest on the podcast to help clear things up and explain the cold, hard science. If you've seen the hundreds of podcasts out there talking about NAD, NMN, and NR and you're still confused - this episode should help.
Podcast notes available here: https://simplebiotechpodcast.com/joseph-baur-nad-nmn-nr/
-James Ruhle, SimpleBioTechPodcast.com
Stay up to date with the latest episodes and BioTech updates by following me on instagram @SimpleBioTech
If you want to know which BioTech companies I'm currently excited about, connect with me on Angel List at Angel.co/jamesruhle
If you're confused about NAD and it's precursors then this is the podcast for you. Dr. Joseph Baur, an Associate Professor of Physiology from University of Pennsylvania, is a leading NAD researcher. His lab currently studies metabolic and signaling pathways by which nutrient intake can influence longevity, with a particular emphasis on NAD and mTOR.
In this interview Joseph breaks down all the questions I've had (and there's a lot) about the miracle molecule, NAD. Joseph helps me to understand why it's such an important molecule, how one can boost NAD levels, and what the data tells us about the different NAD precursors, NMN & NR.
As you may or not know there is quite a bit of debate about which NAD precursors work best, and if they even work at all to boost NAD levels in a way that will extend lifespan in humans. It was an absolute pleasure to have a non biased guest on the podcast to help clear things up and explain the cold, hard science. If you've seen the hundreds of podcasts out there talking about NAD, NMN, and NR and you're still confused - this episode should help.
Podcast notes available here: https://simplebiotechpodcast.com/joseph-baur-nad-nmn-nr/
-James Ruhle, SimpleBioTechPodcast.com
Stay up to date with the latest episodes and BioTech updates by following me on instagram @SimpleBioTech
If you want to know which BioTech companies I'm currently excited about, connect with me on Angel List at Angel.co/jamesruhle
Previous Episode

#6 - Dr. Gregory Bailey - Investing in the Longevity Industry: The Greatest Investment Opportunity in All of Human History
Dr. Gregory Bailey is the CEO of Juvenescence, one of the biggest players in the Longevity industry. Dr. Bailey has a medical degree from the University of Western Ontario and practiced emergency medicine for more than 10 years before entering the world of finance. We talked about all the different things that Juvenescence is working on, as well as some great tips for investing in the capital starved longevity industry. If you want some advice from one of the top investors in the industry, make sure to give this a listen.
Juvenescence has their hands in a lot of different pies... from participating in strategic investments where they know they can add significant value as a company, to launching products like Metabolic Switch, which can instantly turn you into ketosis, due to premier this year.
The longevity industry is starved for cash, but it can be extremely daunting for someone with no formal medical training to make an intelligent investment. Dr. Bailey gives some great advice for getting around this hurdle.
It was an absolute honor to speak with Dr. Gregory Bailey, and the conversation got me more excited than ever to play whatever small part I can in the industry. As his partner Jim Mellon says, this is the greatest investment opportunity in all of human history. Don't sleep on it.
-James Ruhle, SimpleBioTechPodcast.com
Stay up to date with the latest episodes and BioTech updates by following me on instagram @SimpleBioTech
If you want to know which BioTech companies I'm currently excited about, connect with me on Angel List at Angel.co/jamesruhle
Next Episode

#8 - Nick Sinclair - Extending The Health Span of Our Pets: How Improving Our Pets Health Span Will Improve Human Health Span
If you've lived in the twentieth century you've likely, at one point or another, had an attachment to a non human furry friend... and with any attachment comes the inevitable realization that our furry friend is a mere mortal... one that will age, slow down, and become frail in our life time. If this is something you dread, then this episode is for you.
In this day and age we live so closely with our pets that they've become members of the standard twentieth century family... and losing a pet is just like losing a family member. My guest today is a man that is attempting to drastically slow down the aging process of our furry best friends, and to extend the amount of healthy, happy, time that we have with them.
Nick Sinclair is the CEO of Animal Bioscience, one of the 5 daughter companies of famed David Sinclair's Life Biosciences. In this fascinating interview Nick helps explain to me just how they are tackling animal aging, how it's different than tackling human aging, how the discoveries in animal aging will actually help progress the science in human aging, and a plethora of other interesting topics. If you're interested in getting an inside look into the world of Longevity, you'll love this episode.
Podcast notes available here: https://simplebiotechpodcast.com/
-James Ruhle, SimpleBioTechPodcast.com
Stay up to date with the latest episodes and BioTech updates by following me on instagram @SimpleBioTech
If you want to know which BioTech companies I'm currently excited about, connect with me on Angel List at Angel.co/jamesruhle
The Simple BioTech Podcast - #7 - Joseph Baur - NAD, NMN, & NR - A Deep Dive Into NAD & It's Precursors w/ a Leading NAD Researcher
Transcript
If you've been paying attention at all to the world of longevity in the last few years, then you have certainly heard of a little molecule called NAD, a miracle molecule found in all living cells that has been found to be greatly correlated to all facets of healthy lifespan . Unfortunately, as we age, we begin to have less and less NAD available, which causes an assortment of age related diseases.
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