
Episode 67: Longevity, What we know and what we need to know about living longer and better
09/06/23 • 58 min
In this episode we explore our understanding of longevity with a leading longevity researcher.
Guest:
Dr Matt Kaeberlein, PhD
Former Director, Healthy Aging and Longevity Research Institute
Former Director, Biological Mechanisms of Healthy Aging Training Program
Co-Director, UW Nathan Shock Center of Excellence in the Basic Biology of Aging
Co-Director, Dog Aging Project
Professor of Pathology
Adjunct Professor of Genome Sciences
Adjunct Professor of Oral Health Sciences
Dr. Kaeberlein’s research interests are focused on biological mechanisms of aging in order to facilitate translational interventions that promote healthspan and improve quality of life. He has published more than 200 scientific papers, has been recognized by several prestigious awards, and has Fellow status in the American Association for the Advancement of Science (AAAS), the American Aging Association, and the Gerontological Society of America (GSA). Dr. Kaeberlein is currently the CEO of the American Aging Association and has served on the Board of Directors for the Federation of American Societies for Experimental Biology (FASEB), AGE, and GSA. Dr. Kaeberlein is the founding Director of the UW Healthy Aging and Longevity Research Institute, the Director of the UW Nathan Shock Center of Excellence in the Basic Biology of Aging, Former Director of the Biological Mechanisms of Healthy Aging Training Program, and founder and co-Director of the Dog Aging Project.
Recommended Resources:
Twitter @mkaeberlein
Peter Attia: Podcast, book, articles
In this episode we explore our understanding of longevity with a leading longevity researcher.
Guest:
Dr Matt Kaeberlein, PhD
Former Director, Healthy Aging and Longevity Research Institute
Former Director, Biological Mechanisms of Healthy Aging Training Program
Co-Director, UW Nathan Shock Center of Excellence in the Basic Biology of Aging
Co-Director, Dog Aging Project
Professor of Pathology
Adjunct Professor of Genome Sciences
Adjunct Professor of Oral Health Sciences
Dr. Kaeberlein’s research interests are focused on biological mechanisms of aging in order to facilitate translational interventions that promote healthspan and improve quality of life. He has published more than 200 scientific papers, has been recognized by several prestigious awards, and has Fellow status in the American Association for the Advancement of Science (AAAS), the American Aging Association, and the Gerontological Society of America (GSA). Dr. Kaeberlein is currently the CEO of the American Aging Association and has served on the Board of Directors for the Federation of American Societies for Experimental Biology (FASEB), AGE, and GSA. Dr. Kaeberlein is the founding Director of the UW Healthy Aging and Longevity Research Institute, the Director of the UW Nathan Shock Center of Excellence in the Basic Biology of Aging, Former Director of the Biological Mechanisms of Healthy Aging Training Program, and founder and co-Director of the Dog Aging Project.
Recommended Resources:
Twitter @mkaeberlein
Peter Attia: Podcast, book, articles
Previous Episode

Episode 66: Kidney Stones. Diagnosis, Treatment and Prevention
Learn all you need to know about Kidney Stones,who is at risk, the various types of stones and presentations.
Guest:
Robert M. Sweet, MD, FACS, MAMSE
Professor of Urology, Surgery and Bioengineering(adj)
Medical Director UW Medicine Kidney Stone Center
Chief, Division of Healthcare Simulation Sciences
Executive Director of WISH and CREST
University of Washington
Dr. Sweet is a Joint Professor of Urology and Surgery and Adjunct Professor in Bioengineering at the University of Washington. He is the Inaugural Chief of the Division for Healthcare Simulation Science and the Founding Medical Director of the UW Medicine Kidney Stone Center.
Dr. Sweet founded and led the University of Minnesota’s SimPORTAL and cofounded the University of Washington’s ISIS which was renamed the Washington, Wyoming, Alaska, Montana and Idaho Institute for Simulation Technologies (WISH) when he assumed the Executive Director position. He is the PI for all programs in the Center for Research in Education and Simulation Technologies (CREST) including the “Advanced Modular Manikin”
During This Episode We Discuss:
We review the diagnosis and various presentations of stones- Why are some painful and others not so much?
How are Kidney Stones diagnosed? What constitutes a Kidney Stone emergency?
Who has stones that might pass versus stones that require therapy. How are Kidney Stones managed and treated?
How can we prevent Kidney Stones
The role of the Kidney Stone Center
Recommended Resources:
Kidney Stones National Kidney Foundation: https://www.kidney.org/atoz/kidneystones
Next Episode

Episode 68: Rheumatological Diseases
Those aches and pains in your fingers, hand, elbow, toes, foot, ankle and knee, what causes them ? What to do when they seem to be getting more severe and are interfering with your activities? What are the various types of arthritis?
Not all Rheumatological disease is arthritis, what else does this area of medical specialties deal with?
We explore the major Rheumatological diseases with a leading Rheumatologist and experienced clinician, researcher.
Guest:
S. Louis Bridges, Jr., MD, PhD has served as Physician-in-Chief and Chair of the Department of Medicine at Hospital for Special Surgery (HSS) and Chief of the Division of Rheumatology at HSS and at Weill Cornell Medical College since 2020. He is immediate Past President of the Rheumatology Research Foundation and a former member of Executive Committee of the Board of Directors of the American College of Rheumatology (ACR). He received a BS degree from the University of Notre Dame, and an MD degree from Louisiana State University School of Medicine in New Orleans. After serving as a Medicine Resident and Chief Medical Resident at the University of Texas Medical Branch in Galveston, Texas, he completed a fellowship in Rheumatology at UAB, where he also obtained a PhD degree in Microbiology/Immunology. From 2008 to 2020, he was Director of the Division of Clinical Immunology and Rheumatology at the University of Alabama at Birmingham. Dr. Bridges has been named to Best Doctors in America, Castle-Connolly Top Doctors, and to the 2023 New York Super Doctors list. He has received the UAB Department of Medicine’s Max Cooper Award for Research Excellence and the UAB School of Public Health’s Sam Brown Bridge Builder Award. He is former Co-Editor of Arthritis & Rheumatology and past Chair of the NIH Arthritis, Musculoskeletal, and Skin Study Section. His research focus is rheumatoid arthritis susceptibility, autoantibodies, and biomarkers of treatment response. He has authored more than 185 manuscripts, many book chapters, and served as editor of three books.
During This Episode We Discuss:
What are Rheumatological diseases? What differentiates sore joints from Rheumatoid or Osteoarthritis? How do we differentiate , diagnose and treat these diseases?
What are some of the newer therapies?
When should you see a physician about your aches and pains in your joints?
When should you see a Rheumatologist?
What are some of the other major Rheumatological diseases?
What should we know about Lupus, Psoriatic arthritis, and Gout.
If you like this episode you’ll love
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