The Nazi Lies Podcast Ep. 12: Hydroxychloroquine and Ivermectin Cure COVID

Mike Isaacson: Now when you say recommended dose...

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Mike: Welcome to another episode of the Nazi Lies Podcast. Subscribe to our Patreon to get access to early episodes and membership in our book club and Discord. Today we are joined by Dr. Tim Geary, a pharmacoparasitologist or parasitopharmacologist... He studies parasites and makes drugs. He's a professor emeritus at McGill University and still teaches courses at Queen's University Belfast. He's here to talk to us about hydroxychloroquine, ivermectin, and why they probably won't neutralize Coronavirus. Thanks for joining us, Dr. Geary.

Tim Geary: You're welcome, Mike. Please call me Tim.

Mike: Okay, Tim. Before we get into all the science, tell our audience a little bit about what you've done professionally, because you have a very extensive list of bona fides, and I don't really know where to start. [laughs]

Tim: That’s quite all right. Yes, I have been working on the study of drugs, pharmacology, for about 45 years, and most of that time I've been working on chemotherapy of infectious diseases, primarily parasites. This includes work in Africa. Most of my career has been on veterinary parasites or human neglected tropical diseases caused by parasites. During the course of my career I have worked on malaria, and that's where chloroquine and its derivative hydroxychloroquine come from, and also ivermectin, which I have studied for many, many years, both in animals and people.

In full disclosure, Mike, I once did work for the pharmaceutical industry, the animal health arm of a company called up Upjohn that is now known as Zoetis in Kalamazoo, Michigan. [ed. It’s now part of Viatris.] I also consulted and worked with the World Health Organization, with the Bill and Melinda Gates Foundation, and with the Carter Center on various problems of tropical diseases, and I continue to be a consultant for some animal health companies. That's who I am.

Mike: Very good. All right. Now you've done some research on both hydroxychloroquine and ivermectin, correct?

Tim: I have, indeed. I worked on both how they work to kill parasites and also how parasites become resistant to them. I have studied them in clinical settings as well as in the laboratory, and I think I qualify as an expert in both medicines in the indications for which they are used, which is essentially tropical medicine and veterinary parasitology.

Mike: Very good. And you've also been following the misinformation surrounding these two drugs too, right?

Tim: I have, with great interest and concern. There aren't very many people in the world who are experts at drug discovery and drug development for these kinds of conditions. That's unfortunate. But yes, I have followed that, Mike, and I certainly have opinions about where the misinformation came from. It was not a malintention, it was just wrong interpretation and wrong design of some initial experiments that led to inappropriate conclusions in a rush to clinical use.

Mike: Okay, so let's talk about each of these medications and then we'll talk about where the rumors started. So let's start with hydroxychloroquine. Since the beginning of the pandemic almost, it was heralded as a miracle COVID cure but was quickly discovered not to be that. What were its recognised clinical uses?

Tim: So hydroxychloroquine is a derivative of a drug called chloroquine, which was also touted initially as a possible solution to COVID. Chloroquine was a miracle drug for the treatment of malaria. It saved, oh my gosh, millions and millions of lives over the course of its use. It's relatively cheap, it's reasonably safe and it was highly effective against malaria parasites until they evolved resistance to it. It's use for malaria has now diminished remarkably.

Hydroxychloroquine was thought to be a safer alternative with a better sort of safety profile. But it never was really used for malaria. It just never displaced chloroquine. Instead, it found use as kind of an immunomodulator compound for people with systemic lupus erythematosus or lupus as it's commonly known, an autoimmune condition. So hydroxychloroquine for people with lupus does help to reduce symptoms, to reduce worsening of the disease, and it is a valuable drug for that purpose.

Mike: Okay, and how safe is it to experiment with?

Tim: Not very. I mean, it does have side effects, especially when you go over recommended...