059 - Arthritis and Biosimilars

Arthritis: what it is; osteoarthritis vs. inflammatory arthritis; rheumatism; the risks and benefits of treatments // biosimilars, the “generic drugs” of biologics // Q&A: Chris’ qualms about omega-3 supplements for your heart // The Health Canada Ministry of Truth // Natural products claiming to cure cancer

Jingle by Joseph Hackl

Additional original music by Seth Donnelly

Theme music: "Troll of the Mountain Swing" by the Underscore Orkestra.

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Reference:

1) Cochrane review on exercise for arthritis: https://www.ncbi.nlm.nih.gov/pubmed/26405113

2) Aquatic exercise and arthritis: https://www.cochrane.org/CD005523/MUSKEL_aquatic-exercise-people-osteoarthritis-knee-or-hip

3) Weight loss and arthritis improvement: https://www.ncbi.nlm.nih.gov/pubmed/17204567

4) Tylenol meta-analyses:

https://www.bmj.com/content/350/bmj.h1225

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)31744-0/fulltext

5) Review on topical NSAIDs: https://www.cochrane.org/CD007402/SYMPT_topical-non-steroidal-anti-inflammatory-drugs-acute-musculoskeletal-pain-adults

6) Capsaicin as a treatment for chronic pain: https://www.cochrane.org/CD007393/SYMPT_capsaicin-applied-skin-chronic-neuropathic-pain-adults

7) Corticosteroids injections:

https://www.ncbi.nlm.nih.gov/pubmed/26490760

https://www.ncbi.nlm.nih.gov/pubmed/28510679

8) Knee braces and orthotics: https://www.cochrane.org/CD004020/MUSKEL_braces-and-orthoses-for-osteoarthritis-of-the-knee

9) Duloxetien for knee pain: https://www.ncbi.nlm.nih.gov/pubmed/26176791

10) Glucosamine and chondroitin: https://www.nejm.org/doi/10.1056/NEJMoa052771?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dwww.ncbi.nlm.nih.gov

11) Trials fo knee surgery for arthritis: https://www.nejm.org/doi/full/10.1056/NEJMoa1505467

12) The omega-3 for cardiovascular disease meta-analysis: https://www.ncbi.nlm.nih.gov/pubmed/31567003?fbclid=IwAR31Z3qq07L9RULPuvFVyzTKavjgde3Mgl_A2LD7BTtw2u4ZZNvat8wAzEU

13) The CTV report on homeopathy: https://bit.ly/2IlNRSx

14) Bad Science Watch report on natural health products and cancer claims: https://badsciencewatch.ca/natural-health-product-retailers-sell-cancer-cures/

Music Credits:

Meanwhile in Bavaria by Kevin MacLeod

Link: https://filmmusic.io/song/4028-meanwhile-in-bavaria

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