Ep. 6 Science SNiP: Forensic DNA Phenotyping, Predicting Human Appearance
03/28/22 • 27 min
DNA as the "Biological Witness". Forensic DNA Phenotyping predicts the externally visible characteristics - i.e. what a person may look like - from their biological material. It has applications in criminal investigations when other leads have failed, missing persons identification, and anthropological research.
To learn more about the host visit https://practicalforensics.science/
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Links to material discussed in this episode and other links of interest:
King Richard III Identification
Double-murder case example
Missing Person Identification
ACLU Opinion on FDP
Walsh Laboratory
HIrisplex at Erasmus University
Kayser M. Forensic DNA Phenotyping: Predicting human appearance from crime scene material for investigative purposes. Forensic Sci Int Genet. 2015 Sep;18:33-48. doi: 10.1016/j.fsigen.2015.02.003. Epub 2015 Feb 16. PMID: 25716572.
Chaitanya L, Breslin K, Zuñiga S, Wirken L, Pośpiech E, Kukla-Bartoszek M, Sijen T, Knijff P, Liu F, Branicki W, Kayser M, Walsh S. The HIrisPlex-S system for eye, hair and skin colour prediction from DNA: Introduction and forensic developmental validation. Forensic Sci Int Genet. 2018 Jul;35:123-135. doi: 10.1016/j.fsigen.2018.04.004. Epub 2018 Apr 12. PMID: 29753263.
Liu F, van Duijn K, Vingerling JR, Hofman A, Uitterlinden AG, Janssens AC, Kayser M. Eye color and the prediction of complex phenotypes from genotypes. Curr Biol. 2009 Mar 10;19(5):R192-3. doi: 10.1016/j.cub.2009.01.027. PMID: 19278628.
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DNA as the "Biological Witness". Forensic DNA Phenotyping predicts the externally visible characteristics - i.e. what a person may look like - from their biological material. It has applications in criminal investigations when other leads have failed, missing persons identification, and anthropological research.
To learn more about the host visit https://practicalforensics.science/
Join our discussion and let us know your thoughts. E: [email protected]
OR
Join our Facebook Page! https://www.facebook.com/SecretsfromtheCrimeLab
Comments? Feedback? Suggestions? Or if you would like to be a guest?
Get in touch on the Contact PagePlease consider Supporting the show: https://www.buymeacoffee.com/SecretsCrimeLab
Links to material discussed in this episode and other links of interest:
King Richard III Identification
Double-murder case example
Missing Person Identification
ACLU Opinion on FDP
Walsh Laboratory
HIrisplex at Erasmus University
Kayser M. Forensic DNA Phenotyping: Predicting human appearance from crime scene material for investigative purposes. Forensic Sci Int Genet. 2015 Sep;18:33-48. doi: 10.1016/j.fsigen.2015.02.003. Epub 2015 Feb 16. PMID: 25716572.
Chaitanya L, Breslin K, Zuñiga S, Wirken L, Pośpiech E, Kukla-Bartoszek M, Sijen T, Knijff P, Liu F, Branicki W, Kayser M, Walsh S. The HIrisPlex-S system for eye, hair and skin colour prediction from DNA: Introduction and forensic developmental validation. Forensic Sci Int Genet. 2018 Jul;35:123-135. doi: 10.1016/j.fsigen.2018.04.004. Epub 2018 Apr 12. PMID: 29753263.
Liu F, van Duijn K, Vingerling JR, Hofman A, Uitterlinden AG, Janssens AC, Kayser M. Eye color and the prediction of complex phenotypes from genotypes. Curr Biol. 2009 Mar 10;19(5):R192-3. doi: 10.1016/j.cub.2009.01.027. PMID: 19278628.
Want to be on an episode? Have ideas for an episode you would like to hear? Want to sponsor the podcast? General enquiry?
email [email protected]
Previous Episode
Ep. 5 Consent, DNA databases, and misuse of a San Francisco rape victim's DNA.
This week's discussion is all about consent and ethical use of genetic information, including DNA databases. I define and discuss what is meant by consent and informed consent and how it's related to the treatment of Henrietta Lacks and how her story triggered the development of ethical practices in medical science. What are the responsibilities of the forensic geneticist? The law enforcement investigator? What should you think about before volunteering a DNA sample...It's a big topic, and this is only the start if the discussion.
To learn more about the host visit https://practicalforensics.science/
Join our discussion and let us know your thoughts. E: [email protected]
OR
Join our Facebook Page! https://www.facebook.com/SecretsfromtheCrimeLab
Comments? Feedback? Suggestions? Or if you would like to be a guest?
Get in touch on the Contact PageHelpful links and to learn more about the topics covered in this episode:
- Genetic papers containing data from China’s ethnic minorities draw fire
- FBI Quality Assurance Standards
- ANAB guidance for professional responsibility
- Stats on sexual assaults – lack of reporting
- https://www.csofs.org/
- https://www.aafs.org/
- https://nij.ojp.gov/funding/informed-consent-requirements
- https://nij.ojp.gov/funding/common-rule
- https://www.law.cornell.edu/wex/fruit_of_the_poisonous_tree
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Next Episode
Episode 7: Ethics as Lived Practice. Anticipatory Capacity and Ethical Decision-Making in Forensic Genetics with Dr. Matthias Wienroth and Dr. Carole McCartney, Northumbria University, Newcastle upon Tyne
New Technology is great...but let's use it to catch the right person. In this episode I spoke with Professors Dr. Matthias Wienroth and Dr. Carol McCartney, two of the authors of "Ethics as Lived Practice. Anticipatory Capacity and Ethical Decision-Making in Forensic Genetics". It's a fascinating discussion about forensic genetics and the rapidly evolving technologies from the perspective of a social scientist and law professor.
Read the full text article: Ethics as Lived Practice. Anticipatory Capacity and Ethical Decision-Making in Forensic Genetics
Works/News mentioned in the episode:
Nuffield Report. The forensic use of bioinformation: ethical issues
Marper Case - European court rules DNA database breaches human rights
The effectiveness of the UK national DNA database
The murder of Rachel Nickell
Phantom of Heilbron
Dr Carole McCartney is a Professor in the School of Law, Northumbria University. Previously senior lecturer in criminal law and criminal justice at the University of Leeds, and Bond University, Queensland, Australia. Carole has written on Australian justice, Innocence Projects, miscarriages of justice, policing cooperation, and DNA, forensic science and criminal justice more widely. She established an Innocence Project at the University of Leeds in 2005...Learn More about Dr. McCartney
Dr. Matthias Wienroth has been published in numerous peer-reviewed journals, he is a founding member of the of the interdisciplinary scientific initiative on new and emerging forensic genetics technologies WIE-DNA (Germany) ...He is a member of the Society for Social Studies of Science (4S) and the European Association for Studies of Science and Technology (EASST). Since 2015, he has been building an interdisciplinary and international network for the Social Studies of Forensic Science..." Learn More about Dr. Weinroth
Additional works by Dr. Wienroth:
EUROFORGEN and Sense About Science booklet on forensic genetics
https://senseaboutscience.org/wp-content/uploads/2017/01/making-sense-of-forensic-genetics.pdf
Others articles:
- Value beyond scientific validity: let’s RULE (Reliability, Utility, LEgitimacy)
- Governing anticipatory technology practices. Forensic DNA phenotyping and the forensic genetics community in Europe
Misuse of Romani genetic data:
- https://www.nature.com/articles/d41586-021-03416-3
- https://www.nytimes.com/2021/11/17/science/genetics-ethics-roma.html
To learn more about the host visit https://practicalfor
Want to be on an episode? Have ideas for an episode you would like to hear? Want to sponsor the podcast? General enquiry?
email [email protected]
Secrets From the Crime Lab - Ep. 6 Science SNiP: Forensic DNA Phenotyping, Predicting Human Appearance
Transcript
Ep 6
Angela: Hello, and welcome to Secrets from the Crime Lab an educational podcast, where we discuss forensic science and related scientific fields and topics. I'm your host, Angela Swarts. And welcome to the first of our Science SNiPs, where we're going to discuss one specific topic in a little bit more detail than we normally would. And we're going to try to keep it at 15 minutes or less. So we shall see if I am capable of cutting myself short. And the second thing t
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