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Science VC

Science VC

JP Orlov

Science VC explores the intersection of deeptech startups and venture capital. Each episode features conversations with startup founders, venture capitalists, and industry experts. Discover their stories, lessons learned, and predictions for the future.
Learn more about the challenges and opportunities of fundraising for venture-backed startups innovating in agtech, biotech, energy, foodtech, healthtech, and sustainability.

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Top 10 Science VC Episodes

Goodpods has curated a list of the 10 best Science VC episodes, ranked by the number of listens and likes each episode have garnered from our listeners. If you are listening to Science VC for the first time, there's no better place to start than with one of these standout episodes. If you are a fan of the show, vote for your favorite Science VC episode by adding your comments to the episode page.

There is a lot of stigma around psychedelics.
Vicky is the CEO of EYWA, a biotech startup that produces molecules for mental health treatments. In this episode, we discussed the fundraising process for a startup working with psychedelics and the stigma surrounding the industry.
Topics in this episode
0:00 Intro
1:07 Founding EYWA
3:53 Advice for Startup Founders in LATAM
8:51 What is Biosynthesis?
12:34 What Molecules is EYWA Focusing On?
13:35 How to Show Commercial Traction Before Regulatory Approval?
15:03 The Psychedelics Ecosystem
16:26 Scientific Data About Psychedelics
23:51 What is EYWA's Business Model?
25:49 How Does IP Shape an R&D Roadmap?
27:56 Why Use AI and Bioinformatics?
33:27 Regulatory Landscape for Psychedelics
40:14 The Investors' Perception of Psychedelics
44:17 EYWA's Most Recent Funding Round
46:14 Building Relationships with Investors
51:02 EYWA's Fundraising Plans
51:37 Recording a TV Show with Tim and Adam Draper
53:43 What's Next for EYWA
Connect with Vicky on LinkedIn https://www.linkedin.com/in/victoria-costa-paz-a83499b2/
Follow EYWA on LinkedIn https://www.linkedin.com/company/eywabio/posts/?feedView=all
Follow EYWA on Instagram https://www.instagram.com/eywa.bio/
Connect with JP Orlov on LinkedIn https://www.linkedin.com/in/jp-orlov/
Follow Science VC on LinkedIn https://www.linkedin.com/company/science-vc
Follow Science VC on Instagram https://www.instagram.com/science.vc
Subscribe to Science VC on YouTube https://www.youtube.com/@ScienceVC
Subscribe to our Newsletter https://substack.com/@jporlov
Learn how WeArePalta can help your deeptech company communicate its science and impact https://www.wearepalta.com/

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Is it possible to transform carbon emissions into everyday products?
Alex is the CEO of CERT Systems, a Canadian climatetech startup that converts CO2 emissions into high-value chemicals. In this episode, Alex shares his journey from the lab bench to raising non-dilutive capital.
Topics in this episode
0:00 Intro
1:16 Founding CERT Systems
3:14 Why Now for CO2 Conversion?
5:33 Unlocking Commercial Potential
8:52 Communicating Sustainability
10:45 Why Petrochemical Companies Care
13:59 Integrating CERT’s Tech
16:33 Why Investors Should Pay Attention
21:29 Biggest Bottleneck for CO2 Chemicals
24:36 Best Markets for CERT’s Tech
29:14 Scaling from Lab to Market
33:08 First Adopters of CO2 Ethylene
37:07 Ethylene’s Role in Aviation Fuel
41:43 Raising Non-Dilutive Funding
44:28 De-Risking Climate Tech Startups
47:52 Protecting IP in Deeptech
54:15 CERT’s Role in Sustainability’s Future
56:18 What’s Next for CERT?
Connect with Alex on LinkedIn https://www.linkedin.com/in/ipalex/?originalSubdomain=ca
Follow CERT on LinkedIn https://www.linkedin.com/company/co2cert/posts/?feedView=all
Email Alex [email protected]
Connect with JP Orlov on LinkedIn https://www.linkedin.com/in/jp-orlov/
Follow Science VC on LinkedIn https://www.linkedin.com/company/science-vc
Follow Science VC on Instagram https://www.instagram.com/science.vc
Subscribe to Science VC on YouTube https://www.youtube.com/@ScienceVC
Subscribe to our Newsletter https://substack.com/@jporlov
Learn how WeArePalta can help your deeptech company communicate its science and impact https://www.wearepalta.com/

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Why not Tulsa?
Michael is the Founder, CEO, and General Partner of Atento Capital, a pre-seed and seed-stage VC firm focused on partnering with founders to build technology around healthcare, climate-tech, and business services.
Topics in this episode
0:00 Intro
1:13 Michael’s Career Journey: From Founder to VC
4:07 The Origin Story of Atento Capital
5:04 Backing from the George Kaiser Family Foundation
10:13 Why Atento Capital Partnered with GRIDX
12:50 Tulsa’s Startup Ecosystem
20:43 How Being a Founder Shapes Michael’s Investment Approach
25:40 Explaining Science Simply to Investors
30:42 The Convergence of Exponential Technologies
34:19 Capital Concentration in Mega Funds
46:01 What to Include in Effective Investor Updates
48:18 Inside the Atento Capital x GRIDX Demo Day
50:35 What’s Next for Atento Capital
52:02 Connect With Michael
Connect with Michael on LinkedIn https://www.linkedin.com/in/mikebasch/
Follow Atento Capital on LinkedIn https://www.linkedin.com/company/atento-capital/posts/?feedView=all
Visit Atento Capital’s Website https://www.atentocapital.com/
Connect with JP Orlov on LinkedIn https://www.linkedin.com/in/jp-orlov/
Follow Science VC on LinkedIn https://www.linkedin.com/company/science-vc
Follow Science VC on Instagram https://www.instagram.com/science.vc
Subscribe to Science VC on Spotify https://open.spotify.com/show/4XcR1Efx8SUqZqMZROQfQl
Subscribe to our Newsletter https://substack.com/@jporlov
Learn how WeArePalta can help your deeptech company communicate its science and impact https://www.wearepalta.com/

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Are there unique ideas anymore?
Khoa Ma is an Associate Director at Endless Frontier Labs, a program at NYU Stern School of Business for early-stage science and technology startups.
Topics in this episode
0:00 Intro
1:07 Khoa’s Career Path
3:22 How Endless Frontier Labs Evaluates Startups
8:45 What Gets Startups Into Endless Frontier Labs
11:22 Most Impressive Startup Pitch
14:49 Maximizing Mentor Relationships
18:38 Building Investor Connections
26:20 Measuring Success Beyond Funding
29:33 Showing Traction Pre-Revenue
33:16 VC Blind Spots in Deeptech
36:32 Separating Sci-Fi From Reality
39:13 Underrated Deeptech Opportunities
42:31 Communicating Urgency to Investors
45:14 Founders’ Aha Moments
48:50 Best Cold Outreach Examples
51:55 No Unique Ideas Anymore
57:28 Reading Books vs. Doing
1:00:22 Who Should Apply to Endless Frontier Labs
1:01:46 Connect With Khoa
Connect with Khoa on LinkedIn https://www.linkedin.com/in/khoahma/
Follow Endless Frontier Labs on LinkedIn https://www.linkedin.com/company/endlessfrontierlabs/posts/?feedView=all
Connect with JP Orlov on LinkedIn https://www.linkedin.com/in/jp-orlov/
Follow Science VC on LinkedIn https://www.linkedin.com/company/science-vc
Follow Science VC on Instagram https://www.instagram.com/science.vc
Subscribe to Science VC on YouTube https://www.youtube.com/@ScienceVC
Subscribe to our Newsletter https://substack.com/@jporlov
Learn how WeArePalta can help your deeptech company communicate its science and impact https://www.wearepalta.com/

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Why do founders have to be very picky about what VCs they approach?
Gerardo Bluske is the Chief Business Officer of ByBug, a biotech startup that creates therapeutics for animals using black soldier flies. In this episode, Gerardo shares his insights about business development and fundraising.
Topics in this episode
0:00 Intro
1:27 Who Is Gerardo Bluske?
2:13 How Was ByBug Founded?
6:47 What Does ByBug Actually Do?
11:57 ByBug's Business Model Explained
18:41 ByBug's Funding Journey
21:29 How to Stand Out to Investors
25:56 Advice for Founders on Data Rooms
32:03 Inside ByBug's Seed Round
35:57 How to Create Commercial Traction
42:16 The Risks of Not Protecting Your IP Properly
44:49 Will the GMO Regulatory Landscape Change?
49:17 Expanding and Managing an International Team
51:55 What Does Company Culture Really Mean?
54:24 What's Next for ByBug?
Connect with Gerardo on LinkedIn https://www.linkedin.com/in/gerardobluske/
Follow ByBug on LinkedIn https://www.linkedin.com/company/bybug/
Follow ByBug on Instagram https://www.instagram.com/bybug_inc?igsh=Y252ZXU4cWhtNGFm
Connect with JP Orlov on LinkedIn https://www.linkedin.com/in/jp-orlov/
Follow Science VC on LinkedIn https://www.linkedin.com/company/science-vc
Follow Science VC on Instagram https://www.instagram.com/science.vc
Subscribe to Science VC on YouTube https://www.youtube.com/@ScienceVC
Subscribe to our Newsletter https://substack.com/@jporlov
Learn how WeArePalta can help your deeptech company communicate its science and impact https://www.wearepalta.com/

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Biodiversity as an Advantage
Galit is a Managing Partner at Danta Fund, a VC firm that backs early-stage agritech startups in Latin America. Danta Fund has the mission of filling three main voids in Latin America: funding in early-stage agri-tech startups, mentorship to guide their founders, and connection with larger markets to help them grow.
Topics in this episode
0:00 Intro
0:57 Galit’s Path From Founder to VC
5:12 How Danta’s Mentors Help Startups
7:08 Danta’s North Star for Startup Selection
9:24 What Makes an LOI Count
10:37 Helping Startups Enter Global Markets
14:28 How Corporates Can Engage Startups
21:57 Why Danta Passes on Startups
25:08 Common Founder Aha Moments
26:49 Why LPs Join Startup Interviews
31:50 What Founders Miss About VCs
33:35 How LATAM Agtech Differs Globally
38:04 Finding & Validating Customers
41:21 What Drives Demand for Sustainability
44:50 Saying No to High-Risk Startups
47:17 Why Danta Focuses on the U.S.
52:27 Who Should Apply to Danta Fund
53:32 Connect With Galit
Connect with Galit on LinkedIn https://www.linkedin.com/in/galitflasterstein/
Follow Danta Fund on LinkedIn https://www.linkedin.com/company/danta-fund/
Visit Danta Fund's Website and Subscribe to their Newsletter https://dantafund.com/
Email Galit [email protected]
Connect with JP Orlov on LinkedIn https://www.linkedin.com/in/jp-orlov/
Follow Science VC on LinkedIn https://www.linkedin.com/company/science-vc
Follow Science VC on Instagram https://www.instagram.com/science.vc
Subscribe to Science VC on YouTube https://www.youtube.com/@ScienceVC
Subscribe to our Newsletter https://substack.com/@jporlov
Learn how WeArePalta can help your deeptech company communicate its science and impact https://www.wearepalta.com/

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Can a single innovation unlock multiple billion-dollar markets?
Larissa is the CEO of APEXzymes, a Brazilian biotech startup that produces cost-effective enzymes for sustainable industrial applications. During our conversation, Larissa shares her journey from chemical engineering to venture capital and entrepreneurship.
Topics in this episode
0:00 Intro
1:06 From Chemical Engineer to VC to Founder
4:56 Why Leave Venture Capital to Build a Startup?
6:38 How Self-Doubt Can Drive Innovation
8:25 Advice Before Starting APEXzymes
9:34 What Are Enzymes and Why Do They Matter?
12:19 APEXzymes’ Value Proposition
13:40 What Investors Miss About APEXzymes
17:13 Key Markets: Biofuels, Cattle Feed & More
19:48 How Enzymes Boost Productivity and Cut Methane
22:11 Early Commercial Traction
23:58 Communicating Traction to Investors
27:50 Turning Enzyme Strains Into Patentable Assets
32:43 Balancing Focus vs. Market Size
38:12 Lessons from Fundraising and Non-Dilutive Grants
43:33 What GRIDX Saw in APEXzymes
46:05 Building Trust With Co-Founders
49:00 Aligning Weekly Tasks With Long-Term Vision
55:22 What’s Next for APEXzymes?
Follow APEXzymes on LinkedIn https://www.linkedin.com/company/apexzymes/posts/?feedView=all
Connect with Larissa on LinkedIn https://www.linkedin.com/in/larissadefv/
Email Larissa [email protected]
Connect with JP Orlov on LinkedIn https://www.linkedin.com/in/jp-orlov/
Follow Science VC on LinkedIn https://www.linkedin.com/company/science-vc
Follow Science VC on Instagram https://www.instagram.com/science.vc
Subscribe to Science VC on YouTube https://www.youtube.com/@ScienceVC
Subscribe to our Newsletter https://substack.com/@jporlov
Learn how WeArePalta can help your deeptech company communicate its science and impact https://www.wearepalta.com/

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Investors don’t care how fancy your tech is.
Diego is the CEO of Qnity, a pharmatech startup that uses quantum electrochemistry to develop devices for drug discovery and screening. In this episode, we discuss his lessons as a second-time founder and his insights on fundraising in the deeptech space.
Topics in this episode
0:00 Intro
1:26 How Was Qnity Founded?
3:58 What Is Krilltech?
7:39 What Is Smart Money?
9:12 How to Talk About Deeptech to Investors
16:27 How to Build a Product Roadmap
22:49 Creating Interest and Managing Investor Objections
28:15 Advice for Deeptech Founders
31:31 Partnering with Oxford University
34:45 Marketing Strategies for Deeptech Startups
38:51 Understanding the Drug Discovery Market
41:37 Inside Qnity's Fundraising Journey
44:15 Expanding the Team
45:27 Fundraising Milestones for a Seed Round
48:22 Challenges in Building Client Relationships
50:08 How to Find the Right Capital for Your Startup
51:55 The Most Important Trait of a Deeptech Founder
57:29 What's Next for Qnity?
Connect with Diego on LinkedIn https://www.linkedin.com/in/diegostoneaires/?originalSubdomain=br
Follow Qnity on LinkedIn https://www.linkedin.com/company/qnity/posts/?feedView=all
Visit Qnity’s Website http://qnity.bio/
Connect with JP Orlov on LinkedIn https://www.linkedin.com/in/jp-orlov/
Follow Science VC on LinkedIn https://www.linkedin.com/company/science-vc
Follow Science VC on Instagram https://www.instagram.com/science.vc
Subscribe to Science VC on YouTube https://www.youtube.com/@ScienceVC
Subscribe to our Newsletter https://substack.com/@jporlov
Learn how WeArePalta can help your deeptech company communicate its science and impact https://www.wearepalta.com/

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FAQ

How many episodes does Science VC have?

Science VC currently has 8 episodes available.

What topics does Science VC cover?

The podcast is about Venture Capital, Biotech, Entrepreneurship, Startup, Startups, Podcasts, Technology, Science, Business, Innovation and Fundraising.

What is the most popular episode on Science VC?

The episode title 'Why No Idea Is Truly Unique | Leveraging Warm Intros and Mentorships | Communicating Urgency and Opportunities to VCs | Success Beyond Funding | Inside NYU’s Acceleration Program with Khoa Ma, Associate Director @ Endless Frontier Labs | Ep 6' is the most popular.

What is the average episode length on Science VC?

The average episode length on Science VC is 57 minutes.

How often are episodes of Science VC released?

Episodes of Science VC are typically released every 7 days.

When was the first episode of Science VC?

The first episode of Science VC was released on Feb 27, 2025.

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