
PsyDactic
T. Ryan O'Leary
A resource for psychiatrists and other medical or behavioral health professionals interested in exploring the neuroscientific basis of psychiatric disorders, psychopharmacology, neuromodulation, and other psychiatric interventions, as well as discussions of pseudoscience, Bayesian reasoning, ethics, the history of psychiatry, and human psychology in general.
This podcast is not medical advice. It strives to be science communication. Dr. O'Leary is a skeptical thinker who often questions what we think we know. He hopes to open more conversations about what we don't know we don't know.
Find transcripts with show-notes and references on each episodes dedicated page at psydactic.buzzsprout.com.
You can leave feedback at https://www.psydactic.com.
The visual companions, when available, can be found at https://youtube.com/@PsyDactic.
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Top 10 PsyDactic Episodes
Goodpods has curated a list of the 10 best PsyDactic episodes, ranked by the number of listens and likes each episode have garnered from our listeners. If you are listening to PsyDactic for the first time, there's no better place to start than with one of these standout episodes. If you are a fan of the show, vote for your favorite PsyDactic episode by adding your comments to the episode page.

In a Word - Perseveration
PsyDactic
02/26/22 • 9 min
This episode is a quick take in a new intermittent series I am calling “In a Word,” and in this series I hope to dig down into some neuropsychiatric terms that we use every day, but maybe don’t really understand very well. The first word I am taking on is PERSEVERATION. The reason I chose PERSEVERATION is because I see it written in psych notes by med studs and residents frequently, but for you Princess Bride fans out there, “You keep using this word. I don’t not think it means what you think it means.”
Please leave feedback at https://www.psydactic.com or send any comments to [email protected].
References and readings (when available) are posted at the end of each episode transcript, located at psydactic.buzzsprout.com. All opinions expressed in this podcast are exclusively those of the person speaking and should not be confused with the opinions of anyone else. We reserve the right to be wrong. Nothing in this podcast should be treated as individual medical advice.

OCD - Brain space
PsyDactic
01/29/22 • 19 min
This episode explores the brain space of obsessive compulsive disorder (OCD) with a creative journey through neuroanatomy and brain circuitry. I try to make it much less boring than it sounds. After listening to this episode, it is my goal that the listener will understand the complex interactions of the cortico-striatal-thalamo-cortical (CSTC) circuit and have a fuller appreciating of how the brain decides what to do and how to do it.
Please leave feedback at https://www.psydactic.com or send any comments to [email protected].
References and readings (when available) are posted at the end of each episode transcript, located at psydactic.buzzsprout.com. All opinions expressed in this podcast are exclusively those of the person speaking and should not be confused with the opinions of anyone else. We reserve the right to be wrong. Nothing in this podcast should be treated as individual medical advice.

Guns - Starting the Conversation
PsyDactic
06/08/23 • 29 min
Today I talk about guns. More specifically, I talk about talking about guns.
Please leave feedback at https://www.psydactic.com or send any comments to [email protected].
References and readings (when available) are posted at the end of each episode transcript, located at psydactic.buzzsprout.com. All opinions expressed in this podcast are exclusively those of the person speaking and should not be confused with the opinions of anyone else. We reserve the right to be wrong. Nothing in this podcast should be treated as individual medical advice.

Psych GPT
PsyDactic
01/09/23 • 15 min
You may have heard that Dr. Google now has some serious competition. It comes from artificial intelligence. Chat GPT is a text generating program that was trained to respond to prompts from users like you and me. What will it say to our psychiatry patients? I gave it some prompts to find out.
Please leave feedback at https://www.psydactic.com.
References and readings (when available) are posted at the end of each episode transcript, located at psydactic.buzzsprout.com. All opinions expressed in this podcast are exclusively those of the person speaking and should not be confused with the opinions of anyone else. We reserve the right to be wrong. Nothing in this podcast should be treated as individual medical advice.

Neuronal Networks: Depression
PsyDactic
11/03/22 • 29 min
It is unlikely that any model of major depressive disorder is likely to find universal signals among those diagnosed because the symptoms are so diverse. However, it does seem likely that models, such as brain-network models, will be able to identify common dysfunctions among those with similar symptom burdens (for example, those with primarily anhedonic symptoms, dysphoria, or with excessive rumination over their own worthlessness), and then help identify how various modalities may be more or less effective to treat these symptoms specifically.
Please leave feedback at https://www.psydactic.com or send any comments to [email protected].
References and readings (when available) are posted at the end of each episode transcript, located at psydactic.buzzsprout.com. All opinions expressed in this podcast are exclusively those of the person speaking and should not be confused with the opinions of anyone else. We reserve the right to be wrong. Nothing in this podcast should be treated as individual medical advice.

10/23/22 • 38 min
Bipolar disorder is a complex, often debilitating and potentially life threatening illness in which the patient goes from episodes of depression to episodes of mania or hypomania, most often with periods of relative euthymia in between these episodes. The most common way to conceptualize the treatment of bipolar disorder is by phase. The ideal goal would be preventing the distinct manic and depressive episodes. This is done mostly with medications although psychotherapy, lifestyle modifications and even neuromodulation potentially have a role. A particularly difficult aspect of bipolar disorder is treating the acute phase of bipolar depression. Each is treated mostly with psychotropic medication. In this Episode, Dr. DePietro will focus on treating acute bipolar depression.
Please leave feedback at https://www.psydactic.com or send any comments to [email protected].
References and readings (when available) are posted at the end of each episode transcript, located at psydactic.buzzsprout.com. All opinions expressed in this podcast are exclusively those of the person speaking and should not be confused with the opinions of anyone else. We reserve the right to be wrong. Nothing in this podcast should be treated as individual medical advice.

10/05/22 • 20 min
In previous episodes I have tried to draw pictures in your mind (using those fat crayons that babies like to chew on) of some of the brain networks that are important in many mental illnesses. We have talked specifically about the Default Mode Network (that is concerned with imaginal thoughts and self-referential thoughts and memories), the Dorsal and Ventral Attention Networks (that help us to identify and pick out details of both our environment and our thoughts and memories), and the Salience Network (that brings the most important details of our perceptions, thoughts, and memories to the forefront of our mind). What we are missing is a network that takes those salient things, considers alternative options about what they mean and what to do about them, organizes a plan to execute, and motivates us to move. Our Central Executive Network and its connections to the other networks are integral in these processes.
Please leave feedback at https://www.psydactic.com or send any comments to [email protected].
References and readings (when available) are posted at the end of each episode transcript, located at psydactic.buzzsprout.com. All opinions expressed in this podcast are exclusively those of the person speaking and should not be confused with the opinions of anyone else. We reserve the right to be wrong. Nothing in this podcast should be treated as individual medical advice.

09/10/22 • 14 min
What is salience? Fundamentally it is a value judgment that determines where your brain will place its limited resources. There are a lot of things that could draw our attention. The world is full of sights, sounds, smells, pressures, temperatures, stretches. Our mind is full of thoughts. Without a salience network, we wouldn’t know what matters and what doesn’t. We would just randomly scan our thoughts and the environment and hope what we are noticing at any point in time is what will help keep us alive. That is a losing evolutionary strategy.
Please leave feedback at https://www.psydactic.com or send any comments to [email protected].
References and readings (when available) are posted at the end of each episode transcript, located at psydactic.buzzsprout.com. All opinions expressed in this podcast are exclusively those of the person speaking and should not be confused with the opinions of anyone else. We reserve the right to be wrong. Nothing in this podcast should be treated as individual medical advice.

08/24/22 • 12 min
Today, I am going to explore the Attention Networks, which are the parts of our brain that get really excited when, for example, we see something that we have never seen before, something that appears to be moving on its own volition (and might harm us), something that appears out of place (like an eyeball on the floor), or something that reminds us of something we really want (I’ll let you pick the example).
Please leave feedback at https://www.psydactic.com or send any comments to [email protected].
References and readings (when available) are posted at the end of each episode transcript, located at psydactic.buzzsprout.com. All opinions expressed in this podcast are exclusively those of the person speaking and should not be confused with the opinions of anyone else. We reserve the right to be wrong. Nothing in this podcast should be treated as individual medical advice.

Bush Francis versus the DSM
PsyDactic
06/14/22 • 20 min
I originally promised a review of the Bush Francis Catatonia Rating Scale, but while reviewing it, I came across some questions that I think are even more interesting. I will discuss Bush Francis, but I want to do it in a larger context of the challenges that Psychiatrists face with diagnosis in general.
Please leave feedback at https://www.psydactic.com or send any comments to [email protected].
References and readings (when available) are posted at the end of each episode transcript, located at psydactic.buzzsprout.com. All opinions expressed in this podcast are exclusively those of the person speaking and should not be confused with the opinions of anyone else. We reserve the right to be wrong. Nothing in this podcast should be treated as individual medical advice.
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FAQ
How many episodes does PsyDactic have?
PsyDactic currently has 71 episodes available.
What topics does PsyDactic cover?
The podcast is about Health & Fitness, Medical Student, Neuroscience, Psychology, Mental Health, Medicine, Psych, Podcasts, Medical Education and Psychiatry.
What is the most popular episode on PsyDactic?
The episode title 'Neuronal Networks: Depression' is the most popular.
What is the average episode length on PsyDactic?
The average episode length on PsyDactic is 27 minutes.
How often are episodes of PsyDactic released?
Episodes of PsyDactic are typically released every 12 days, 17 hours.
When was the first episode of PsyDactic?
The first episode of PsyDactic was released on Dec 29, 2021.
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